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Brwd1 recombinant protein :: Bromodomain and WD repeat-containing protein 1 (Brwd1), partial Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1298001 Brwd1 recombinant protein
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 Product Name   

Bromodomain and WD repeat-containing protein 1 (Brwd1), partial, Recombinant Protein

 Also Known As   

Recombinant Mouse Bromodomain and WD repeat-containing protein 1 (Brwd1), partial

 Product Synonym Names    Bromodomain and WD repeat-containing protein 1; WD repeat-containing protein 9
 Product Gene Name   

Brwd1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Brwd1; Wdr9 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q921C3
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Brwd1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Brwd1 recombinant protein

   This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats, and the function of this protein is not known. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates 3 transcript variants diverging at the 3 ends.
NCBI/Uniprot data below describe general gene information for Brwd1. It may not necessarily be applicable to this product.
 NCBI GI #    157057182
 NCBI GeneID    93871
 NCBI Accession #    NP_001096649.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001103179.1 [Other Products]
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 UniProt Primary Accession #    Q921C3 [Other Products]
 UniProt Secondary Accession #    Q921C2; E9QAC1 [Other Products]
 UniProt Related Accession #    Q921C3 [Other Products]
 Molecular Weight    253,957 Da
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 NCBI Official Full Name    bromodomain and WD repeat-containing protein 1 isoform B
 NCBI Official Synonym Full Names    bromodomain and WD repeat domain containing 1
 NCBI Official Symbol    Brwd1 [Similar Products]
 NCBI Official Synonym Symbols   
Wdr9; repro5; G1-403-16; 5330419I02Rik; D530019K20Rik
[Similar Products]
 NCBI Protein Information    bromodomain and WD repeat-containing protein 1; WD repeat domain 9; WD repeat-containing protein 9
 UniProt Protein Name    Bromodomain and WD repeat-containing protein 1
 UniProt Synonym Protein Names   
WD repeat-containing protein 9
 Protein Family    Bromodomain and WD repeat-containing protein
 UniProt Gene Name    Brwd1 [Similar Products]
 UniProt Synonym Gene Names    Wdr9 [Similar Products]
 UniProt Entry Name    BRWD1_MOUSE
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 UniProt Comments for Brwd1    WDR9: an ubiquitously expressed WD40 repeat protein that may be a transcriptional activator and be involved in chromatin remodeling. Interacts with SMARCA4. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Three alternatively spliced human isoforms have been described.

Protein type: Transcription factor

Cellular Component: cytoplasm; nucleolus; nucleus

Molecular Function: protein binding

Biological Process: regulation of transcription from RNA polymerase II promoter; regulation of cell shape; transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoskeleton organization and biogenesis
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 Research Articles on Brwd1    1. Brwd1 represents one of a small number of genes whose elimination disrupts gametogenesis in both sexes after the major events of meiotic prophase I have been completed.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Brwd1 recombinant proteinDiseases associated with Brwd1 recombinant protein
 Products by Pathway  Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1 publications with Brwd1 and Necrosis
Organs/Tissues associated with Brwd1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with Brwd1 and Brain
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