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Ccl12 recombinant protein :: C-C motif chemokine 12 (Ccl12) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1406151 Ccl12 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $475 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $630 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $650 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $695 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $805 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $875 +1 FREE 8GB USB
1 mg (E-Coli)  /  $980 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $990 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,015 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,045 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,475 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,490 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,595 +1 FREE 8GB USB
1 mg (Baculovirus)  /  $1,980 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C-C motif chemokine 12 (Ccl12), Recombinant Protein

 Also Known As   

Recombinant Mouse C-C motif chemokine 12 (Ccl12)

 Product Synonym Names    C-C motif chemokine 12; MCP-1-related chemokine; Monocyte chemoattractant protein 5; Monocyte chemotactic protein 5; MCP-5; Small-inducible cytokine A12
 Product Gene Name   

Ccl12 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Ccl12; Mcp5; Scya12 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    23-104aa; full length protein
 Sequence    GPDAVSTP VTCCYNVVKQ KIHVRKLKSY RRITSSQCPR EAVIFRTILD KEICADPKEK WVKNSINHLD KTSQTFILEP SCLG
 3D Structure    ModBase 3D Structure for Q62401
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Ccl12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Ccl12. It may not necessarily be applicable to this product.
 NCBI GI #    119226206
 NCBI GeneID    20293
 NCBI Accession #    NP_035461.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_011331.2 [Other Products]
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 UniProt Primary Accession #    Q62401 [Other Products]
 UniProt Secondary Accession #    Q9QYD6 [Other Products]
 UniProt Related Accession #    Q62401 [Other Products]
 Molecular Weight    11,659 Da
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 NCBI Official Full Name    C-C motif chemokine 12
 NCBI Official Synonym Full Names    chemokine (C-C motif) ligand 12
 NCBI Official Symbol    Ccl12 [Similar Products]
 NCBI Official Synonym Symbols   
MCP-5; Scya12
[Similar Products]
 NCBI Protein Information    C-C motif chemokine 12; MCP-1-related chemokine; small inducible cytokine A12; small-inducible cytokine A12; monocyte chemotactic protein 5; monocyte chemoattractant protein 5
 UniProt Protein Name    C-C motif chemokine 12
 UniProt Synonym Protein Names   
MCP-1-related chemokine; Monocyte chemoattractant protein 5; Monocyte chemotactic protein 5; MCP-5; Small-inducible cytokine A12
 Protein Family    C-C motif chemokine
 UniProt Gene Name    Ccl12 [Similar Products]
 UniProt Synonym Gene Names    Mcp5; Scya12; MCP-5 [Similar Products]
 UniProt Entry Name    CCL12_MOUSE
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 UniProt Comments for Ccl12    CCL2: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Chemokine; Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Cellular Component: extracellular space; extracellular region; intracellular

Molecular Function: CCR2 chemokine receptor binding; chemokine activity; cytokine activity

Biological Process: positive regulation of leukocyte migration; cytokine and chemokine mediated signaling pathway; MAPKKK cascade; cytoskeleton organization and biogenesis; chemotaxis; macrophage chemotaxis; monocyte chemotaxis; regulation of cell shape; lipopolysaccharide-mediated signaling pathway; protein kinase B signaling cascade; immune response; angiogenesis; negative regulation of neuron apoptosis; inflammatory response; astrocyte cell migration
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 Research Articles on Ccl12    1. After 100% O2 treatment, genes involved in inflammation (Ccl12), angiogenesis (Igfr1, Stat3), and metabolism (Hk2) were upregulated.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Ccl12 recombinant proteinDiseases associated with Ccl12 recombinant protein
 Products by Pathway  Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >32 publications with Ccl12 and Inflammation
 Disease Models, Animal Antibodies  >22 publications with Ccl12 and Disease Models, Animal
 Respiratory Tract Diseases Antibodies  >14 publications with Ccl12 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >13 publications with Ccl12 and Lung Diseases
 Fibrosis Antibodies  >12 publications with Ccl12 and Fibrosis
 Necrosis Antibodies  >10 publications with Ccl12 and Necrosis
 Hypersensitivity Antibodies  >9 publications with Ccl12 and Hypersensitivity
 Pulmonary Fibrosis Antibodies  >8 publications with Ccl12 and Pulmonary Fibrosis
 Neoplasms, Experimental Antibodies  >5 publications with Ccl12 and Neoplasms, Experimental
 Respiratory Hypersensitivity Antibodies  >5 publications with Ccl12 and Respiratory Hypersensitivity
Organs/Tissues associated with Ccl12 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >13 publications with Ccl12 and Brain
 Spleen Antibodies  >5 publications with Ccl12 and Spleen
 Thymus Antibodies  >4 publications with Ccl12 and Thymus
 Embryonic Tissue Antibodies  >2 publications with Ccl12 and Embryonic Tissue
 Prostate Antibodies  >2 publications with Ccl12 and Prostate
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