NP_001278397.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
Molecular Weight
11,008 Da
NCBI Official Full Name
C-C motif chemokine 4-like isoform 1
NCBI Official Synonym Full Names
C-C motif chemokine ligand 4 like 2
NCBI Official Synonym Symbols
CCL4L; SCYA4L; AT744.2; SCYQ4L2 [Similar Products]
NCBI Protein Information
C-C motif chemokine 4-like
UniProt Protein Name
C-C motif chemokine 4-like
UniProt Synonym Protein Names
Lymphocyte activation gene 1 protein; LAG-1; Macrophage inflammatory protein 1-beta; MIP-1-beta; Monocyte adherence-induced protein 5-alpha; Small-inducible cytokine A4-like
UniProt Synonym Gene Names
NCBI Summary for CCL4L1
This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this family member is similar to the chemokine (C-C motif) ligand 4 product, which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals, where most individuals have one to five copies. This gene copy contains a non-consensus splice acceptor site at the 3' terminal exon found in other highly similar gene copies, and it thus uses other alternative splice sites for the 3' terminal exon, resulting in multiple transcript variants. [provided by RefSeq, Apr 2014]
UniProt Comments for CCL4L1
Chemokine that induces chemotaxis of cells expressing CCR5 or CCR1. Inhibits HIV replication in peripheral blood monocytes that express CCR5.
Research Articles on CCL4L1
Precautions
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Disclaimer
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Pathways associated with CCL4L1 recombinant protein
Diseases associated with CCL4L1 recombinant protein
Organs/Tissues associated with CCL4L1 recombinant protein
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