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CRP recombinant protein :: C-Reactive Protein (CRP), Recombinant Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS319381 CRP recombinant protein
Unit / Price
1 mg  /  $420 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C-Reactive Protein (CRP), Recombinant, Recombinant Protein

 Also Known As   

Human CRP, Recombinant

 Product Synonym Names    Human C-Reactive Protein (CRP), Recombinant
Recombinant Human C-Reactive Protein (CRP), pentamer structure.
 Product Gene Name   

CRP recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 1; NC_000001.10 (159682079..159684379, complement). Location: 1q21-q23
 OMIM    123260
 3D Structure    ModBase 3D Structure for P02741
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 Host    E Coli
 Species Reactivity    Human
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 Specificity    C-Reactive Protein (CRP), Recombinant
 Purity/Purification    Phosphorylcholine affinity purification
Purity: Single band at 1ug/lane
 Form/Format    Purified, Liquid
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 Inactivation    Not applicable
 Buffer    20mM Tris-HCl, pH 7.5 containing 0.14M Sodium chloride, 2mM CaCl2
 Preservative    0.05% Sodium azide
 Warnings    This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
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 Preparation and Storage    Store at 2 to 8 degree C. DO NOT FREEZE!
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CRP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for CRP recombinant protein    Purified Proteins and Bioactive Peptides
NCBI/Uniprot data below describe general gene information for CRP. It may not necessarily be applicable to this product.
 NCBI GI #    117486
 NCBI GeneID    1401
 NCBI Accession #    P02741.1 [Other Products]
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 UniProt Primary Accession #    P02741 [Other Products]
 UniProt Secondary Accession #    Q08AK3; Q8WW75; A8K078; D3DVD9; D3DVE0 [Other Products]
 UniProt Related Accession #    P02741; Q5VVP7 [Other Products]
 Molecular Weight    25,039 Da [Similar Products]
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 NCBI Official Full Name    C-reactive protein
 NCBI Official Synonym Full Names    C-reactive protein, pentraxin-related
 NCBI Official Symbol    CRP [Similar Products]
 NCBI Official Synonym Symbols   
PTX1; MGC88244; MGC149895
[Similar Products]
 NCBI Protein Information    C-reactive protein; pentraxin 1; OTTHUMP00000033307
 UniProt Protein Name    C-reactive protein
 Protein Family    Cryparin
 UniProt Gene Name    CRP [Similar Products]
 UniProt Synonym Gene Names    PTX1 [Similar Products]
 UniProt Entry Name    CRP_HUMAN
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 NCBI Summary for CRP    The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq]
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 UniProt Comments for CRP    Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.

Cofactor: Binds 2 calcium ions per subunit.

Subunit structure: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.

Subcellular location: Secreted.

Tissue specificity: Found in plasma.

Induction: The concentration of CRP in plasma increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL1/interleukin-1 and IL6//interleukin-6.

Miscellaneous: This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium.

Sequence similarities: Belongs to the pentaxin family.Contains 1 pentaxin domain.

Mass spectrometry: Molecular mass is 23028 Da from positions 19 - 224. Determined by MALDI. Ref.15Molecular mass is 22930 Da from positions 19 - 223. Determined by MALDI. Ref.15
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 Research Articles on CRP    1. Findings indicate that IL-6 is a powerful independent predictor of future CV events in high-risk Japanese patients, suggesting its predictive value is superior to hs-CRP.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CRP recombinant proteinPathways associated with CRP recombinant protein
 Reference Product  PubMed Publications
 CFH recombinant protein  >16 publications with CRP and CFH
 APCS recombinant protein  >6 publications with CRP and APCS
 FCGR2A recombinant protein  >5 publications with CRP and FCGR2A
 FCGR1A recombinant protein  >5 publications with CRP and FCGR1A
 LEP recombinant protein  >3 publications with CRP and LEP
 FCGR2B recombinant protein  >3 publications with CRP and FCGR2B
 GP6 recombinant protein  >2 publications with CRP and GP6
 Products by Pathway  Pathway Diagram
 Classical Antibody-mediated Complement Activation Pathway antibodies  Classical Antibody-mediated Complement Activation Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 IL6-mediated Signaling Events Pathway antibodies  IL6-mediated Signaling Events Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immunity Signaling Pathway antibodies  Innate Immunity Signaling Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
Diseases associated with CRP recombinant proteinOrgans/Tissues associated with CRP recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7583 publications with CRP and Inflammation
 Cardiovascular Diseases Antibodies  >6047 publications with CRP and Cardiovascular Diseases
 Heart Diseases Antibodies  >2949 publications with CRP and Heart Diseases
 Myocardial Ischemia Antibodies  >2438 publications with CRP and Myocardial Ischemia
 Coronary Disease Antibodies  >2198 publications with CRP and Coronary Disease
 Autoimmune Diseases Antibodies  >1763 publications with CRP and Autoimmune Diseases
 Arteriosclerosis Antibodies  >1560 publications with CRP and Arteriosclerosis
 Diabetes Mellitus Antibodies  >1330 publications with CRP and Diabetes Mellitus
 Insulin Resistance Antibodies  >1267 publications with CRP and Insulin Resistance
 Obesity Antibodies  >1201 publications with CRP and Obesity
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >13407 publications with CRP and Blood
 Liver Antibodies  >947 publications with CRP and Liver
 Muscle Antibodies  >834 publications with CRP and Muscle
 Lung Antibodies  >710 publications with CRP and Lung
 Brain Antibodies  >607 publications with CRP and Brain
 Pancreas Antibodies  >111 publications with CRP and Pancreas
 Placenta Antibodies  >36 publications with CRP and Placenta
 Bladder Antibodies  >36 publications with CRP and Bladder
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