NP_058792.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
C-reactive protein
NCBI Official Synonym Full Names
C-reactive protein, pentraxin-related
NCBI Official Synonym Symbols
Aa1249; Ac1262; Ab1-341; Ab2-196; Ac1-114; Ac2-069; Ba2-693 [Similar Products]
NCBI Protein Information
C-reactive protein; C-reactive protein, petaxin related; C-reactive protein member of the pentraxin family; C-reactive protein, member of the pentraxin family
UniProt Protein Name
C-reactive protein
UniProt Synonym Gene Names
UniProt Entry Name
CRP_RAT
NCBI Summary for CRP
glycoprotein of the acute phase response [RGD, Feb 2006]
UniProt Comments for CRP
Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells
By similarity.
Cofactor: Binds 2 calcium ions per subunit
By similarity.
Subunit structure: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits. Two of the five chains form a dimer linked by two interchain disulfide bonds located in the C-terminal heptapeptide and specific to rat CRP.
Subcellular location: Secreted.
Tissue specificity: Found in plasma.
Post-translational modification: The last two cysteines are involved either in interchain disulfide bonds or in an intrachain bond.
Sequence similarities: Belongs to the pentaxin family.Contains 1 pentaxin domain.
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Products associated with CRP recombinant protein
Pathways associated with CRP recombinant protein
Diseases associated with CRP recombinant protein
Organs/Tissues associated with CRP recombinant protein
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