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Apobec1 recombinant protein :: C->U-editing enzyme APOBEC-1 (Apobec1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1109990 Apobec1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $630 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $775 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $845 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $920 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $930 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,040 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,160 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,160 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,175 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,315 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,675 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,765 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,785 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,235 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C->U-editing enzyme APOBEC-1 (Apobec1), Recombinant Protein

 Also Known As   

Recombinant Rat C->U-editing enzyme APOBEC-1 (Apobec1)

 Product Synonym Names    C->U-editing enzyme APOBEC-1; EC=3.5.4.-; Apolipoprotein B mRNA-editing enzyme 1
 Product Gene Name   

Apobec1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-229aa; full length protein
 Sequence    MSSETGPVAV DPTLRRRIEP HEFEVFFDPR ELRKETCLLY EINWGGRHSI WRHTSQNTNK HVEVNFIEKF TTERYFCPNT RCSITWFLSW SPCGECSRAI TEFLSRYPHV TLFIYIARLY HHADPRNRQG LRDLISSGVT IQIMTEQESG YCWRNFVNYS PSNEAHWPRY PHLWVRLYVL ELYCIILGLP PCLNILRRKQ PQLTFFTIAL QSCHYQRLPP HILWATGLK
 3D Structure    ModBase 3D Structure for P38483
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rattus norvegicus (Rat)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Apobec1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Apobec1 recombinant protein

   This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs.
NCBI/Uniprot data below describe general gene information for Apobec1. It may not necessarily be applicable to this product.
 NCBI GI #    6978519
 NCBI GeneID    25383
 NCBI Accession #    NP_037039.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012907.2 [Other Products]
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 UniProt Primary Accession #    P38483 [Other Products]
 UniProt Related Accession #    P38483 [Other Products]
 Molecular Weight    27,274 Da
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 NCBI Official Full Name    C->U-editing enzyme APOBEC-1
 NCBI Official Synonym Full Names    apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
 NCBI Official Symbol    Apobec1 [Similar Products]
 NCBI Official Synonym Symbols   
REPR
[Similar Products]
 NCBI Protein Information    C->U-editing enzyme APOBEC-1; Apolipoprotein B editing protein; apolipoprotein B editing complex 1; apolipoprotein B mRNA-editing enzyme 1
 UniProt Protein Name    C->U-editing enzyme APOBEC-1
 UniProt Synonym Protein Names   
Apolipoprotein B mRNA-editing enzyme 1
 Protein Family    C->U-editing enzyme
 UniProt Gene Name    Apobec1 [Similar Products]
 UniProt Entry Name    ABEC1_RAT
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 NCBI Summary for Apobec1    required for post transcriptional editing of apolipoprotein B mRNA [RGD, Feb 2006]
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 UniProt Comments for Apobec1    APOBEC1: apolipoprotein B mRNA editing enzyme. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. Expressed exclusively in the small intestine.

Protein type: EC 3.5.4.-; Hydrolase; RNA-binding; Cell cycle regulation; RNA processing

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; cytosine deaminase activity; zinc ion binding; RNA binding; AU-rich element binding; cytidine deaminase activity

Biological Process: response to drug; cytidine metabolic process; mRNA stabilization; lipoprotein metabolic process; response to osmotic stress; regulation of cell proliferation; response to ethanol; cellular response to insulin stimulus; cytidine to uridine editing; lipoprotein biosynthetic process; response to zinc ion; lipoprotein transport; mRNA modification; response to gamma radiation; cytidine deamination; response to calcium ion; mRNA processing; defense response to virus
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 Research Articles on Apobec1    1. Apobec-1 increased COX-2 expression and COX-2 mRNA stabilization in neurogenic cells, and failed to catalyze C-to-U editing of COX-2 mRNA
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Apobec1 recombinant proteinPathways associated with Apobec1 recombinant protein
 Reference Product  PubMed Publications
 A1cf recombinant protein  >6 publications with Apobec1 and A1cf
 Ung recombinant protein  >1 publications with Apobec1 and Ung
 Products by Pathway  Pathway Diagram
 Formation Of The Editosome Pathway antibodies  Formation Of The Editosome Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 MRNA Editing Pathway antibodies  MRNA Editing Pathway Diagram
 MRNA Editing: C To U Conversion Pathway antibodies  MRNA Editing: C To U Conversion Pathway Diagram
Diseases associated with Apobec1 recombinant proteinOrgans/Tissues associated with Apobec1 recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >9 publications with Apobec1 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >3 publications with Apobec1 and Nervous System Diseases
 Heart Diseases Antibodies  >2 publications with Apobec1 and Heart Diseases
 Liver Diseases Antibodies  >2 publications with Apobec1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with Apobec1 and Carcinoma, Hepatocellular
 Adenocarcinoma Antibodies  >2 publications with Apobec1 and Adenocarcinoma
 Brain Diseases Antibodies  >1 publications with Apobec1 and Brain Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with Apobec1 and Cell Transformation, Neoplastic
 Inflammation Antibodies  >1 publications with Apobec1 and Inflammation
 Hypertension Antibodies  >1 publications with Apobec1 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >4 publications with Apobec1 and Heart
 Lung Antibodies  >2 publications with Apobec1 and Lung
 Brain Antibodies  >2 publications with Apobec1 and Brain
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