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CXCL13 recombinant protein :: C-X-C motif chemokine 13 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS717261
SDS-PAGE
Unit / Price
0.01 mg  /  $135 +1 FREE 8GB USB
0.05 mg  /  $195 +1 FREE 8GB USB
0.2 mg  /  $465 +1 FREE 8GB USB
0.5 mg  /  $815 +1 FREE 8GB USB
1 mg  /  $1,290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C-X-C motif chemokine 13 (CXCL13), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant rat C-X-C motif chemokine 13 protein

 Product Synonym Names    Angie; B cell-attracting chemokine 1; BCA-1; B lymphocyte chemoattractant; CXC chemokine BLC; Small-inducible cytokine B13
 Product Gene Name   

CXCL13 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRS
 Chromosome Location    Chromosome: 4; NC_000004.11 (78432907..78532988). Location: 4q21
 OMIM    605149
 3D Structure    ModBase 3D Structure for O43927
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 Host    E Coli
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 Purity/Purification    95% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C. For extended storage,conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CXCL13 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CXCL13 recombinant protein

   Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5.
 Applications Tested/Suitable for CXCL13 recombinant protein   

SDS-PAGE, ELISA (EIA), Western Blot (WB)

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 SDS-PAGE of CXCL13 recombinant protein    CXCL13 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for CXCL13. It may not necessarily be applicable to this product.
 NCBI GI #    194733765
 NCBI GeneID    10563
 NCBI Accession #    NP_006410.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006419.2 [Other Products]
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 UniProt Primary Accession #    O43927 [Other Products]
 UniProt Related Accession #    O43927 [Other Products]
 Molecular Weight    35 KD [Similar Products]
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 NCBI Official Full Name    Homo sapiens chemokine (C-X-C motif) ligand 13 (CXCL13), mRNA
 NCBI Official Synonym Full Names    chemokine (C-X-C motif) ligand 13
 NCBI Official Symbol    CXCL13 [Similar Products]
 NCBI Official Synonym Symbols   
BLC; BCA1; ANGIE; BCA-1; BLR1L; ANGIE2; SCYB13
[Similar Products]
 NCBI Protein Information    C-X-C motif chemokine 13; CXC chemokine BLC; B-cell chemoattractant; B-lymphocyte chemoattractant; b lymphocyte chemoattractant; small-inducible cytokine B13; B-cell-attracting chemokine 1; b cell-attracting chemokine 1; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1); small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant)
 UniProt Protein Name    C-X-C motif chemokine 13
 UniProt Synonym Protein Names   
Angie; B cell-attracting chemokine 1; BCA-1; B lymphocyte chemoattractant; CXC chemokine BLC; Small-inducible cytokine B13
 Protein Family    C-X-C motif chemokine
 UniProt Gene Name    CXCL13 [Similar Products]
 UniProt Synonym Gene Names    BCA1; BLC; SCYB13; BCA-1 [Similar Products]
 UniProt Entry Name    CXL13_HUMAN
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 NCBI Summary for CXCL13    B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CXCL13    Function: Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5.

Subcellular location: Secreted.

Tissue specificity: Highest levels in liver, followed by spleen, lymph node, appendix and stomach. Low levels in salivary gland, mammary gland and fetal spleen.

Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.
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 Research Articles on CXCL13    1. Neuromyelitis optica patients with higher relapse rates exhibit higher CXCL13 concentrations in their cerebrospinal fluid (CSF) as well as a trend of increased disease disability with increased CSF CXCL13 levels.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CXCL13 recombinant proteinPathways associated with CXCL13 recombinant protein
 Reference Product  PubMed Publications
 CXCR5 recombinant protein  >144 publications with CXCL13 and CXCR5
 CCL21 recombinant protein  >106 publications with CXCL13 and CCL21
 CCL19 recombinant protein  >83 publications with CXCL13 and CCL19
 CXCR3 recombinant protein  >21 publications with CXCL13 and CXCR3
 CCR10 recombinant protein  >2 publications with CXCL13 and CCR10
 FGF2 recombinant protein  >1 publications with CXCL13 and FGF2
 CCRL1 recombinant protein  >1 publications with CXCL13 and CCRL1
 Products by Pathway  Pathway Diagram
 CXCR3-mediated Signaling Events Pathway antibodies  CXCR3-mediated Signaling Events Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
Diseases associated with CXCL13 recombinant proteinOrgans/Tissues associated with CXCL13 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >113 publications with CXCL13 and Neoplasms
 Inflammation Antibodies  >93 publications with CXCL13 and Inflammation
 Necrosis Antibodies  >44 publications with CXCL13 and Necrosis
 Disease Models, Animal Antibodies  >29 publications with CXCL13 and Disease Models, Animal
 Death Antibodies  >24 publications with CXCL13 and Death
 Lung Diseases Antibodies  >19 publications with CXCL13 and Lung Diseases
 Carcinoma Antibodies  >18 publications with CXCL13 and Carcinoma
 Brain Diseases Antibodies  >15 publications with CXCL13 and Brain Diseases
 Kidney Diseases Antibodies  >15 publications with CXCL13 and Kidney Diseases
 Hyperplasia Antibodies  >15 publications with CXCL13 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >152 publications with CXCL13 and Lymph Node
 Spleen Antibodies  >66 publications with CXCL13 and Spleen
 Bone Antibodies  >56 publications with CXCL13 and Bone
 Vascular Antibodies  >53 publications with CXCL13 and Vascular
 Lung Antibodies  >29 publications with CXCL13 and Lung
 Kidney Antibodies  >20 publications with CXCL13 and Kidney
 Pharynx Antibodies  >20 publications with CXCL13 and Pharynx
 Intestine Antibodies  >17 publications with CXCL13 and Intestine
 Muscle Antibodies  >14 publications with CXCL13 and Muscle
 Embryonic Tissue Antibodies  >10 publications with CXCL13 and Embryonic Tissue
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