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CXCL5 recombinant protein :: C-X-C motif chemokine 5 protein (CXCL5) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS969186
SDS-PAGE
Unit / Price
0.005 mg  /  $115 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
0.1 mg  /  $430 +1 FREE 8GB USB
0.25 mg  /  $725 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C-X-C motif chemokine 5 protein (CXCL5), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human C-X-C motif chemokine 5 protein (CXCL5) (Active)

 Product Synonym Names    ENA-78; Epithelial-derived neutrophil-activating protein 78; Neutrophil-activating peptide ENA-78; Small-inducible cytokine B5;
 Product Gene Name   

CXCL5 recombinant protein

[Similar Products]
 Product Synonym Gene Name    ENA78; SCYB5 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    41-114aa, Partial
 Sequence    AAVLRELRCV CLQTTQGVHP KMISNLQVFA IGPQCSKVEV VASLKNGKEI CLDPEAPFLK KVIQKILDGG NKEN
 OMIM    X78686 mRNA
 3D Structure    ModBase 3D Structure for P42830
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 Host    E Coli
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 Purity/Purification    >=97% as determined by SDS-PAGE and HPLC. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
 Biological Activity    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration of 5.0-10 ng/ml.
 Storage Buffer    0.2 um filtered PBS, pH 7.4,lyophilized
 Endotoxin    Less than 1.0 EU/ug as determined by LAL method.
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 Preparation and Storage    Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CXCL5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CXCL5 recombinant protein

   Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. {ECO:0000269|PubMed:10095777}.
 Product Categories/Family for CXCL5 recombinant protein    Biological Active Protein; Immunology; Chemokine
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 SDS-PAGE of CXCL5 recombinant protein    CXCL5 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for CXCL5. It may not necessarily be applicable to this product.
 NCBI GI #    4506849
 NCBI GeneID    6374
 NCBI Accession #    NP_002985.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002994.4 [Other Products]
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 UniProt Primary Accession #    P42830 [Other Products]
 UniProt Secondary Accession #    Q96QE1 [Other Products]
 UniProt Related Accession #    P42830 [Other Products]
 Molecular Weight    8.1 kDa
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 NCBI Official Full Name    C-X-C motif chemokine 5
 NCBI Official Synonym Full Names    C-X-C motif chemokine ligand 5
 NCBI Official Symbol    CXCL5 [Similar Products]
 NCBI Official Synonym Symbols   
SCYB5; ENA-78
[Similar Products]
 NCBI Protein Information    C-X-C motif chemokine 5
 UniProt Protein Name    C-X-C motif chemokine 5
 UniProt Synonym Protein Names   
ENA-78(1-78); Epithelial-derived neutrophil-activating protein 78; Neutrophil-activating peptide ENA-78; Small-inducible cytokine B5
 Protein Family    C-X-C motif chemokine
 UniProt Gene Name    CXCL5 [Similar Products]
 UniProt Synonym Gene Names    ENA78; SCYB5 [Similar Products]
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 NCBI Summary for CXCL5    This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]
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 UniProt Comments for CXCL5    CXCL5: Involved in neutrophil activation. In vitro, ENA-78(8- 78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular region; extracellular space

Molecular Function: chemokine activity; CXCR chemokine receptor binding

Biological Process: cell-cell signaling; chemotaxis; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; neutrophil mediated immunity; positive regulation of cell proliferation; response to lipopolysaccharide; signal transduction
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 Research Articles on CXCL5    1. Two haplotype blocks, one upstream to the coding region of UGT2A1 (rs146712414, P = 9.1 x 10(-5); odds ratio [OR], 1.34; 95% confidence interval [CI], 1.16-1.56) and one downstream of the genes PF4/PPBP/CXCL5 (rs1595009, P = 1.3 x 10(-4); OR, 1.32; 95% CI, 1.15-1.52), were associated with AgP.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CXCL5 recombinant proteinPathways associated with CXCL5 recombinant protein
 Reference Product  PubMed Publications
 CXCR2 recombinant protein  >95 publications with CXCL5 and CXCR2
 CCL5 recombinant protein  >85 publications with CXCL5 and CCL5
 CXCL10 recombinant protein  >67 publications with CXCL5 and CXCL10
 CCL20 recombinant protein  >46 publications with CXCL5 and CCL20
 CXCL12 recombinant protein  >34 publications with CXCL5 and CXCL12
 CXCR1 recombinant protein  >27 publications with CXCL5 and CXCR1
 CXCL11 recombinant protein  >25 publications with CXCL5 and CXCL11
 CXCR3 recombinant protein  >16 publications with CXCL5 and CXCR3
 CXCL13 recombinant protein  >16 publications with CXCL5 and CXCL13
 CCL19 recombinant protein  >8 publications with CXCL5 and CCL19
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
Diseases associated with CXCL5 recombinant proteinOrgans/Tissues associated with CXCL5 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >274 publications with CXCL5 and Inflammation
 Necrosis Antibodies  >112 publications with CXCL5 and Necrosis
 Respiratory Tract Diseases Antibodies  >109 publications with CXCL5 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >99 publications with CXCL5 and Lung Diseases
 Disease Models, Animal Antibodies  >79 publications with CXCL5 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >48 publications with CXCL5 and Cardiovascular Diseases
 Fibrosis Antibodies  >31 publications with CXCL5 and Fibrosis
 Liver Diseases Antibodies  >30 publications with CXCL5 and Liver Diseases
 Pneumonia Antibodies  >29 publications with CXCL5 and Pneumonia
 Lung Neoplasms Antibodies  >27 publications with CXCL5 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >336 publications with CXCL5 and Blood
 Lung Antibodies  >148 publications with CXCL5 and Lung
 Vascular Antibodies  >105 publications with CXCL5 and Vascular
 Intestine Antibodies  >40 publications with CXCL5 and Intestine
 Skin Antibodies  >34 publications with CXCL5 and Skin
 Brain Antibodies  >21 publications with CXCL5 and Brain
 Kidney Antibodies  >20 publications with CXCL5 and Kidney
 Uterus Antibodies  >17 publications with CXCL5 and Uterus
 Connective Tissue Antibodies  >17 publications with CXCL5 and Connective Tissue
 Embryonic Tissue Antibodies  >15 publications with CXCL5 and Embryonic Tissue
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