NP_005848.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,813 Da
NCBI Official Full Name
CAAX prenyl protease 1 homolog
NCBI Official Synonym Full Names
zinc metallopeptidase STE24
NCBI Official Synonym Symbols
HGPS; PRO1; FACE1; STE24; FACE-1; Ste24p [Similar Products]
NCBI Protein Information
CAAX prenyl protease 1 homolog
UniProt Protein Name
CAAX prenyl protease 1 homolog
UniProt Synonym Protein Names
Farnesylated proteins-converting enzyme 1; FACE-1; Prenyl protein-specific endoprotease 1; Zinc metalloproteinase Ste24 homolog
UniProt Synonym Gene Names
NCBI Summary for ZMPSTE24
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]
UniProt Comments for ZMPSTE24
Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.
Research Articles on ZMPSTE24
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Products associated with ZMPSTE24 recombinant protein
Pathways associated with ZMPSTE24 recombinant protein
Diseases associated with ZMPSTE24 recombinant protein
Organs/Tissues associated with ZMPSTE24 recombinant protein
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