NP_002974
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
10.0 kDa (90aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
NCBI Official Full Name
C-C motif chemokine 3
NCBI Official Synonym Full Names
C-C motif chemokine ligand 3
NCBI Official Synonym Symbols
MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha [Similar Products]
NCBI Protein Information
C-C motif chemokine 3
UniProt Protein Name
C-C motif chemokine 3
UniProt Synonym Protein Names
G0/G1 switch regulatory protein 19-1; Macrophage inflammatory protein 1-alpha; MIP-1-alpha
UniProt Synonym Gene Names
NCBI Summary for CCL3
This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]
UniProt Comments for CCL3
Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Product References and Citations for CCL3 recombinant protein
Guan E, et al. (2001) J Biol Chem. 276:12404-9; Cocchi F., et al. (1995) Science. 270:1811-5.
Research Articles on CCL3
Precautions
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Disclaimer
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Products associated with CCL3 recombinant protein
Pathways associated with CCL3 recombinant protein
Diseases associated with CCL3 recombinant protein
Organs/Tissues associated with CCL3 recombinant protein
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