Q8HY01.1
[Other Products]
UniProt Primary Accession #
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[Other Products]
Molecular Weight
45,562 Da
NCBI Official Full Name
CD209 antigen
UniProt Protein Name
CD209 antigen
UniProt Synonym Protein Names
Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN1; CD_antigen: CD209
UniProt Synonym Gene Names
UniProt Comments for CD209
Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens ().
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