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CD30 recombinant protein

Scan QR to view Datasheet Catalog #    MBS146353 CD30 recombinant protein
Unit / Price
0.002 mg  /  $140 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $5,015 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD30, Recombinant Protein

 Also Known As   

Recombinant Human CD30

 Product Synonym Names    CD30 Human; CD30 Human Recombinant; CD30; D1S166E; KI-1; Tumor necrosis factor receptor superfamily member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; TNFRSF8
 Product Gene Name   

CD30 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHH HHH SSGLVPRGSH MGSFPQ DRPF EDTCHGNPSH YYDKAVRRCC YRCPMGLFPT QQCPQRPTDC RKQCEPDYYL DEADRCTACV TCSRDDLVEK TPCAWNSSRV CECRPGMFCS TSAVNSCARC FFHSVCPAGM IVKFPGTAQK NTVCEPASPG VSPACASPEN CKEPSSGTIP QAKPTPVSPA TSSASTMPVR GGTRLAQEAA SKLTRAPDSP SSVGRPSSDP GLSPTQPCPE GSGDCRKQCE PDYYLDEAGR CTACVSCSRD DLVEKTPCAW NSSRTCECRP GMICATSATN SCARCVPYPI CAAETVTKPQ DMAEKDTTFE APPLGTQPDC NPTPENGEAP ASTSPTQSLL VDSQASKTLP IPTSAPVALS STGK
 OMIM    153243
 3D Structure    ModBase 3D Structure for P28908
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 Host    E Coli
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 Purity/Purification    Greater than 85% as determined by SDS-PAGE.
 Form/Format    CD30 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sterile Filtered colorless solution.
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 Other Notes    Small volumes of CD30 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CD30 recombinant protein

   Description: CD30 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 384 amino acids (19-379a.a.) and having a molecular mass of 40.8kDa. CD30 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: Tumor necrosis factor receptor superfamily member 8 (CD30) is a member of the TNF-receptor superfamily. CD30 is expressed by activated (not by resting) T and B cells. CD30 interacts with TRAF2 and TRAF5 which mediate the signal transduction that leads to the activation of NF-kappaB. CD30 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
 Product Categories/Family for CD30 recombinant protein    RECOMBINANT & NATURAL PROTEINS; CD Antigens
NCBI/Uniprot data below describe general gene information for CD30. It may not necessarily be applicable to this product.
 NCBI GI #    597709795
 NCBI GeneID    943
 NCBI Accession #    NP_001234.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_001243.4 [Other Products]
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 UniProt Primary Accession #    P28908 [Other Products]
 UniProt Secondary Accession #    Q6P4D9; B1AN79; B9EGD9; D3YTD8 [Other Products]
 UniProt Related Accession #    P28908 [Other Products]
 Molecular Weight    50,935 Da
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 NCBI Official Full Name    tumor necrosis factor receptor superfamily member 8 isoform 1
 NCBI Official Synonym Full Names    tumor necrosis factor receptor superfamily, member 8
 NCBI Official Symbol    TNFRSF8 [Similar Products]
 NCBI Official Synonym Symbols   
CD30; Ki-1; D1S166E
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 8; CD30L receptor; Ki-1 antigen; cytokine receptor CD30; lymphocyte activation antigen CD30
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 8
 UniProt Synonym Protein Names   
CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD_antigen: CD30
 Protein Family    CD302 antigen
 UniProt Gene Name    TNFRSF8 [Similar Products]
 UniProt Synonym Gene Names    CD30; D1S166E [Similar Products]
 UniProt Entry Name    TNR8_HUMAN
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 NCBI Summary for CD30    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD30    TNFRSF8: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B. 2 isoforms of the human protein are produced by alternative initiation.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: cytoplasm; plasma membrane; integral to membrane

Molecular Function: transmembrane receptor activity

Biological Process: positive regulation of tumor necrosis factor biosynthetic process; negative regulation of cell proliferation; positive regulation of apoptosis; positive regulation of TRAIL biosynthetic process; signal transduction
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 Research Articles on CD30    1. Data indicate a chimeric fusion involving nucleophosmin NPM1 (5q35) and TYK2 kinase (19p13) that encodes an NPM1-TYK2 protein in cutaneous CD30 antigen-positve lymphoproliferative disorders.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CD30 recombinant proteinPathways associated with CD30 recombinant protein
 Reference Product  PubMed Publications
 ALK recombinant protein  >185 publications with CD30 and ALK
 TNFSF8 recombinant protein  >95 publications with CD30 and TNFSF8
 TRAF2 recombinant protein  >36 publications with CD30 and TRAF2
 TRAF1 recombinant protein  >27 publications with CD30 and TRAF1
 TRAF3 recombinant protein  >13 publications with CD30 and TRAF3
 JUNB recombinant protein  >13 publications with CD30 and JUNB
 TRAF5 recombinant protein  >10 publications with CD30 and TRAF5
 CCL4 recombinant protein  >3 publications with CD30 and CCL4
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 TNF-alpha/NF-kB Signaling Pathway antibodies  TNF-alpha/NF-kB Signaling Pathway Diagram
Diseases associated with CD30 recombinant proteinOrgans/Tissues associated with CD30 recombinant protein
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >1842 publications with CD30 and Immune System Diseases
 Hodgkin Disease Antibodies  >579 publications with CD30 and Hodgkin Disease
 Necrosis Antibodies  >312 publications with CD30 and Necrosis
 Carcinoma Antibodies  >132 publications with CD30 and Carcinoma
 Neoplasms, Experimental Antibodies  >109 publications with CD30 and Neoplasms, Experimental
 Inflammation Antibodies  >91 publications with CD30 and Inflammation
 Cell Transformation, Neoplastic Antibodies  >63 publications with CD30 and Cell Transformation, Neoplastic
 Fever Antibodies  >63 publications with CD30 and Fever
 Hyperplasia Antibodies  >56 publications with CD30 and Hyperplasia
 Cardiovascular Diseases Antibodies  >48 publications with CD30 and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1167 publications with CD30 and Blood
 Lymph Node Antibodies  >352 publications with CD30 and Lymph Node
 Lung Antibodies  >74 publications with CD30 and Lung
 Intestine Antibodies  >28 publications with CD30 and Intestine
 Testis Antibodies  >23 publications with CD30 and Testis
 Embryonic Tissue Antibodies  >23 publications with CD30 and Embryonic Tissue
 Uterus Antibodies  >7 publications with CD30 and Uterus
 Salivary Gland Antibodies  >2 publications with CD30 and Salivary Gland
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