NP_001814.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,644 Da
NCBI Official Full Name
creatine kinase B-type
NCBI Official Synonym Full Names
creatine kinase, brain
NCBI Official Synonym Symbols
BCK; B-CK; CKBB; HEL-211; HEL-S-29 [Similar Products]
NCBI Protein Information
creatine kinase B-type
UniProt Protein Name
Creatine kinase B-type
UniProt Synonym Protein Names
B-CK; Creatine kinase B chain
UniProt Synonym Gene Names
UniProt Entry Name
KCRB_HUMAN
NCBI Summary for CKBB
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]
UniProt Comments for CKBB
CKB: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family.
Protein type: EC 2.7.3.2; Kinase, other; Amino Acid Metabolism - arginine and proline
Chromosomal Location of Human Ortholog: 14q32
Cellular Component: mitochondrion; cytosol
Molecular Function: protein binding; creatine kinase activity; ATP binding
Biological Process: substantia nigra development; cellular chloride ion homeostasis; phosphorylation; creatine metabolic process
Research Articles on CKBB
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Products associated with CKBB recombinant protein
Pathways associated with CKBB recombinant protein
Diseases associated with CKBB recombinant protein
Organs/Tissues associated with CKBB recombinant protein
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