NP_001815.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,101 Da
NCBI Official Full Name
creatine kinase M-type
NCBI Official Synonym Full Names
creatine kinase, muscle
NCBI Official Synonym Symbols
NCBI Protein Information
creatine kinase M-type
UniProt Protein Name
Creatine kinase M-type
UniProt Synonym Protein Names
Creatine kinase M chain; M-CK
UniProt Synonym Gene Names
UniProt Entry Name
KCRM_HUMAN
NCBI Summary for CKMM
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]
UniProt Comments for CKMM
CKM: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family.
Protein type: Kinase, other; Amino Acid Metabolism - arginine and proline; EC 2.7.3.2
Chromosomal Location of Human Ortholog: 19q13.32
Cellular Component: cytosol
Molecular Function: creatine kinase activity; ATP binding
Biological Process: phosphocreatine biosynthetic process; creatine metabolic process; phosphorylation
Research Articles on CKMM
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Products associated with CKMM recombinant protein
Pathways associated with CKMM recombinant protein
Diseases associated with CKMM recombinant protein
Organs/Tissues associated with CKMM recombinant protein
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