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CNTFR recombinant protein

Scan QR to view Datasheet Catalog #    MBS205884
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CNTFR, Recombinant Protein

★Popular Item★
 Also Known As   

CNTFR, 23-342aa, Human, His tag, E Coli (Denatured)

 Product Synonym Names    Ciliary neurotrophic factor receptor subunit alpha; CNTFR-alpha; CNTFR Alpha; CNTF receptor
 Product Gene Name   

CNTFR recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MQRHSPQEAP HVQYERLGSD VTLPCGTANW DAAVTWRVNG TDLAPDLLNG SQLVLHGLEL GHSGLYACFH RDSWHLRHQV LLHVGLPPRE PVLSCRSNTY PKGFYCSWHL PTPTYIPNTF NVTVLHGSKI MVCEKDPALK NRCHIRYMHL FSTIKYKVSI SVSNALGHNA TAITFDEFTI VKPDPPENVV ARPVPSNPRR LEVTWQTPST WPDPESFPLK FFLRYRPLIL DQWQHVELSD GTAHTITDAY AGKEYIIQVA AKDNEIGTWS DWSVAAHATP WTEEPRHLTT EAQAAETTTS TTSSLAPPPT TKICDPGELG S
 OMIM    M73238 mRNA
 3D Structure    ModBase 3D Structure for P26992
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 Host    E Coli
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 Purity/Purification    > 85% by SDS-PAGE
 Form/Format    Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol
 Concentration    1mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of CNTFR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CNTFR recombinant protein

   CNTFR also known as Ciliary neurotrophic factor receptor subunit alpha. This protein binds to CNTF. The alpha subunit provides the receptor specificity. Recombinant human CNTFR protein, was expressed in E Coli
 Product Categories/Family for CNTFR recombinant protein    Neuroscience
 Applications Tested/Suitable for CNTFR recombinant protein   

SDS-PAGE

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 SDS-Page of CNTFR recombinant protein    CNTFR recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for CNTFR. It may not necessarily be applicable to this product.
 NCBI GI #    4502931
 NCBI GeneID    1271
 NCBI Accession #    NP_001833 [Other Products]
 NCBI GenBank Nucleotide #    NM_001842.4 [Other Products]
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 UniProt Primary Accession #    P26992 [Other Products]
 UniProt Secondary Accession #    Q5U050 [Other Products]
 UniProt Related Accession #    P26992 [Other Products]
 Molecular Weight    38.1kDa (341aa)
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 NCBI Official Full Name    ciliary neurotrophic factor receptor subunit alpha preproprotein
 NCBI Official Synonym Full Names    ciliary neurotrophic factor receptor
 NCBI Official Symbol    CNTFR [Similar Products]
 NCBI Protein Information    ciliary neurotrophic factor receptor subunit alpha
 UniProt Protein Name    Ciliary neurotrophic factor receptor subunit alpha
 Protein Family    Ciliary neurotrophic factor receptor
 UniProt Gene Name    CNTFR [Similar Products]
 UniProt Synonym Gene Names    CNTF receptor subunit alpha; CNTFR-alpha [Similar Products]
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 NCBI Summary for CNTFR    This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]
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 UniProt Comments for CNTFR    Binds to CNTF. The alpha subunit provides the receptor specificity.
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Product References and Citations for CNTFR recombinant protein

   Davis S., et al. (1991). Science 253:59-63; Valenzuela D.M., et al. (1995). Genomics 25:157-163
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 Research Articles on CNTFR    1. The family-based study showed no association between the CNTFR rs7036351, NET rs3785143 polymorphisms, and attention-deficit hyperactivity disorder.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CNTFR recombinant proteinPathways associated with CNTFR recombinant protein
 Reference Product  PubMed Publications
 CNTF recombinant protein  >120 publications with CNTFR and CNTF
 LIFR recombinant protein  >44 publications with CNTFR and LIFR
 OSM recombinant protein  >26 publications with CNTFR and OSM
 IL6ST recombinant protein  >18 publications with CNTFR and IL6ST
 CRLF1 recombinant protein  >6 publications with CNTFR and CRLF1
 JAK1 recombinant protein  >3 publications with CNTFR and JAK1
 JAK2 recombinant protein  >3 publications with CNTFR and JAK2
 CLCF1 recombinant protein  >3 publications with CNTFR and CLCF1
 TYK2 recombinant protein  >1 publications with CNTFR and TYK2
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 IL-6-type Cytokine Receptor Ligand Interactions Pathway antibodies  IL-6-type Cytokine Receptor Ligand Interactions Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interleukin-6 Family Signaling Pathway antibodies  Interleukin-6 Family Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Signaling By Interleukins Pathway antibodies  Signaling By Interleukins Pathway Diagram
Diseases associated with CNTFR recombinant proteinOrgans/Tissues associated with CNTFR recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >15 publications with CNTFR and Nervous System Diseases
 Disease Models, Animal Antibodies  >7 publications with CNTFR and Disease Models, Animal
 Nerve Degeneration Antibodies  >5 publications with CNTFR and Nerve Degeneration
 Inflammation Antibodies  >5 publications with CNTFR and Inflammation
 Brain Injuries Antibodies  >5 publications with CNTFR and Brain Injuries
 Vascular Diseases Antibodies  >5 publications with CNTFR and Vascular Diseases
 Lung Diseases Antibodies  >3 publications with CNTFR and Lung Diseases
 Fibrosis Antibodies  >3 publications with CNTFR and Fibrosis
 Necrosis Antibodies  >3 publications with CNTFR and Necrosis
 Hypertrophy Antibodies  >2 publications with CNTFR and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >59 publications with CNTFR and Nerve
 Brain Antibodies  >34 publications with CNTFR and Brain
 Muscle Antibodies  >28 publications with CNTFR and Muscle
 Embryonic Tissue Antibodies  >10 publications with CNTFR and Embryonic Tissue
 Eye Antibodies  >10 publications with CNTFR and Eye
 Ganglia Antibodies  >7 publications with CNTFR and Ganglia
 Heart Antibodies  >3 publications with CNTFR and Heart
 Kidney Antibodies  >2 publications with CNTFR and Kidney
 Connective Tissue Antibodies  >1 publications with CNTFR and Connective Tissue
 Testis Antibodies  >1 publications with CNTFR and Testis
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