NP_031693.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
88,215 Da
NCBI Official Full Name
cadherin-8 isoform 2 preproprotein
NCBI Official Synonym Full Names
cadherin 8
NCBI Protein Information
cadherin-8
UniProt Protein Name
Cadherin-8
UniProt Entry Name
CADH8_MOUSE
NCBI Summary for Cdh8
This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Mice lacking the encoded protein exhibit reduced behavioral responses to cold, but not thermal stimuli. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 8. [provided by RefSeq, Oct 2015]
UniProt Comments for Cdh8
CDH8: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Protein type: Cell adhesion; Membrane protein, integral
Cellular Component: nerve terminal
Biological Process: response to cold; synaptic transmission; synaptic transmission, glutamatergic
Research Articles on Cdh8
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Products associated with Cdh8 recombinant protein
Pathways associated with Cdh8 recombinant protein
Diseases associated with Cdh8 recombinant protein
Organs/Tissues associated with Cdh8 recombinant protein
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