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CALB2 recombinant protein :: Calbindin-2 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS142956 CALB2 recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.025 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $2,665 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Calbindin-2 (CALB2), Recombinant Protein

 Also Known As   

Recombinant Human Calbindin-2

 Product Synonym Names    CALB2 Human; Calbindin-2 Human Recombinant; Calretinin; CR; CALB2; CAB29; CAL2; CaBP29K; 29 kDa calbindin
 Product Gene Name   

CALB2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHH HHH SSGLVPRGSH MAGPQQQPPY LHLAELTASQ FLEIWKHFDA DGNGYIEGKE LENFFQELEK ARKGSGMMSK SDNFGEKMKE FMQKYDKNSD GKIEMAELAQ ILPTEENFLL CFRQHVGSST EFMEAWRKYD TDRSGYIEAN ELKGFLSDLL KKANRPYDEP KLQEYTQTIL RMFDLNGDGK LGLSEMSRLL PVQENFLLKF QGMKLTSEEF NAIFTFYDKD RSGYIDEHEL DALLKDLYEK NKKEMNIQQL TNYRKSVMSL AEAGKLYRKD LEIVLCSEPP M
 OMIM    114051
 3D Structure    ModBase 3D Structure for P22676
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 Host    E Coli
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 Purity/Purification    Greater than 95% as determined by SDS-PAGE.
 Form/Format    The CALB2 1mg/ml protein solution contains 20mM Tris-HCl buffer pH-8 & 10% glycerol.
Sterile Filtered colorless solution.
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 Preparation and Storage    Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
 Other Notes    Small volumes of CALB2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CALB2 recombinant protein

   Description: CALB2 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 211 amino acids (1-271 a.a.) and having a molecular mass of 33.7kDa.The CALB2 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
 Product Categories/Family for CALB2 recombinant protein    RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Calbindin
NCBI/Uniprot data below describe general gene information for CALB2. It may not necessarily be applicable to this product.
 NCBI GI #    153946409
 NCBI GeneID    794
 NCBI Accession #    NP_001731.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001740.4 [Other Products]
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 UniProt Primary Accession #    P22676 [Other Products]
 UniProt Secondary Accession #    Q53HD2; Q96BK4; A8K4Y1 [Other Products]
 UniProt Related Accession #    P22676 [Other Products]
 Molecular Weight    31,540 Da
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 NCBI Official Full Name    calretinin isoform 1
 NCBI Official Synonym Full Names    calbindin 2
 NCBI Official Symbol    CALB2 [Similar Products]
 NCBI Official Synonym Symbols   
CR; CAL2; CAB29
[Similar Products]
 NCBI Protein Information    calretinin; 29 kDa calbindin; calbindin 2, (29kD, calretinin); calbindin D29K
 UniProt Protein Name    Calretinin
 UniProt Synonym Protein Names   
29 kDa calbindin
 Protein Family    Calretinin
 UniProt Gene Name    CALB2 [Similar Products]
 UniProt Synonym Gene Names    CAB29; CR [Similar Products]
 UniProt Entry Name    CALB2_HUMAN
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 NCBI Summary for CALB2    This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
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 UniProt Comments for CALB2    CALB2: Calretinin is a calcium-binding protein which is abundant in auditory neurons. Belongs to the calbindin family.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 16q22.2

Cellular Component: cytoplasm; gap junction; nucleus

Molecular Function: calcium ion binding

Biological Process: cytosolic calcium ion homeostasis
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 Research Articles on CALB2    1. Calretinin positivity was observed in all rectal biopsies of Hirschsprung disease showing the presence of ganglion cells, and the staining was consistently absent in all cases of aganglionosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CALB2 recombinant proteinDiseases associated with CALB2 recombinant protein
 Reference Product  PubMed Publications
 CHAT recombinant protein  >49 publications with CALB2 and CHAT
 BDNF recombinant protein  >13 publications with CALB2 and BDNF
 SP8 recombinant protein  >4 publications with CALB2 and SP8
 DLX1 recombinant protein  >3 publications with CALB2 and DLX1
 SST recombinant protein  >3 publications with CALB2 and SST
 CA7 recombinant protein  >1 publications with CALB2 and CA7
 GAD1 recombinant protein  >1 publications with CALB2 and GAD1
 PVALB recombinant protein  >1 publications with CALB2 and PVALB
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >138 publications with CALB2 and Nervous System Diseases
 Brain Diseases Antibodies  >108 publications with CALB2 and Brain Diseases
 Ovarian Neoplasms Antibodies  >56 publications with CALB2 and Ovarian Neoplasms
 Nerve Degeneration Antibodies  >50 publications with CALB2 and Nerve Degeneration
 Disease Models, Animal Antibodies  >44 publications with CALB2 and Disease Models, Animal
 Mental Disorders Antibodies  >44 publications with CALB2 and Mental Disorders
 Gastrointestinal Diseases Antibodies  >36 publications with CALB2 and Gastrointestinal Diseases
 Seizures Antibodies  >28 publications with CALB2 and Seizures
 Movement Disorders Antibodies  >23 publications with CALB2 and Movement Disorders
 Pain Antibodies  >19 publications with CALB2 and Pain
Organs/Tissues associated with CALB2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >691 publications with CALB2 and Brain
 Nerve Antibodies  >433 publications with CALB2 and Nerve
 Eye Antibodies  >79 publications with CALB2 and Eye
 Embryonic Tissue Antibodies  >58 publications with CALB2 and Embryonic Tissue
 Intestine Antibodies  >47 publications with CALB2 and Intestine
 Lung Antibodies  >43 publications with CALB2 and Lung
 Ovary Antibodies  >41 publications with CALB2 and Ovary
 Testis Antibodies  >20 publications with CALB2 and Testis
 Heart Antibodies  >16 publications with CALB2 and Heart
 Stomach Antibodies  >13 publications with CALB2 and Stomach
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