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CAMK1 recombinant protein :: Calcium/Calmodulin Dependent Protein Kinase I Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2034255 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $210 +1 FREE 8GB USB
0.1 mg  /  $310 +1 FREE 8GB USB
0.2 mg  /  $385 +1 FREE 8GB USB
0.5 mg  /  $735 +1 FREE 8GB USB
1 mg  /  $1,080 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Calcium/Calmodulin Dependent Protein Kinase I (CAMK1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Calcium/Calmodulin Dependent Protein Kinase I (CAMK1)

 Product Synonym Names    CAMKI; CaM kinase I alpha
 Product Gene Name   

CAMK1 recombinant protein

[Similar Products]
 Matching Pairs    Antibody: Calcium/Calmodulin Dependent Protein Kinase I (MBS2033841)
Antigen: Calcium/Calmodulin Dependent Protein Kinase I (MBS2034255)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604998
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 Host    E Coli
 Species Reactivity    Human
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 Purity/Purification    >92%
 Form/Format    20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
 Concentration    200ug/mL (lot specific)
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 Source    Prokaryotic expression
 Residues    Met1~Leu370
 Tags    N-terminal His-Tag
 Subcellular Location    Cytoplasm
 Traits    Freeze-dried powder
    
 Predicted isoelectric point    5.1
 Predicted Molecular Mass    45.0kDa
 Accurate Molecular Mass    45kDa as determined by SDS-PAGE reducing conditions
 Usage    Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex
    
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8 degree C for one month.
Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of CAMK1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for CAMK1 recombinant protein   

SDS-PAGE, WB, ELISA, IP, CoIP, Purification, Amine Reactive Labeling.

(May be suitable for use in other assays to be determined by the end user.)

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 Sequence of CAMK1 recombinant protein    CAMK1 recombinant protein Sequence image
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 SDS-PAGE of CAMK1 recombinant protein    CAMK1 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for CAMK1. It may not necessarily be applicable to this product.
 NCBI GI #    4502553
 NCBI GeneID    8536
 NCBI Accession #    NP_003647.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003656.4 [Other Products]
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 UniProt Secondary Accession #    Q3KPF6 [Other Products]
 UniProt Related Accession #    Q14012 [Other Products]
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 NCBI Official Full Name    calcium/calmodulin-dependent protein kinase type 1
 NCBI Official Synonym Full Names    calcium/calmodulin dependent protein kinase I
 NCBI Official Symbol    CAMK1 [Similar Products]
 NCBI Official Synonym Symbols   
CAMKI
[Similar Products]
 NCBI Protein Information    calcium/calmodulin-dependent protein kinase type 1
 UniProt Protein Name    Calcium/calmodulin-dependent protein kinase type 1
 UniProt Synonym Protein Names   
CaM kinase I; CaM-KI; CaM kinase I alpha; CaMKI-alpha
 Protein Family    Calcium/calmodulin-dependent serine/threonine-protein kinase
 UniProt Gene Name    CAMK1 [Similar Products]
 UniProt Synonym Gene Names    CaM-KI; CaMKI-alpha [Similar Products]
 UniProt Entry Name    KCC1A_HUMAN
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 NCBI Summary for CAMK1    Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CAMK1    CAMK1A: an ubiquitous protein kinase of the CAMK1 family. Activated by Ca(2+)/calmodulin. Must be phosphorylated to be maximally active. Substrates include synapsin I.

Protein type: Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.17; Kinase, protein; CAMK group; CAMK1 family

Chromosomal Location of Human Ortholog: 3p25.3

Cellular Component: cytoplasm; nucleus

Molecular Function: ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; protein binding

Biological Process: cell cycle; negative regulation of protein binding; nucleocytoplasmic transport; positive regulation of muscle cell differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein export from nucleus; positive regulation of synapse structural plasticity; positive regulation of syncytium formation by plasma membrane fusion; positive regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; regulation of muscle cell differentiation; regulation of protein binding; regulation of protein localization; signal transduction
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 Research Articles on CAMK1    1. CAMK1 functional regulation subnetwork in hepatocellular carcinoma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CAMK1 recombinant proteinDiseases associated with CAMK1 recombinant protein
 Products by Pathway  Pathway Diagram
 Aldosterone Synthesis And Secretion Pathway antibodies  Aldosterone Synthesis And Secretion Pathway Diagram
 Aldosterone Synthesis And Secretion Pathway antibodies  Aldosterone Synthesis And Secretion Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Oxytocin Signaling Pathway antibodies  Oxytocin Signaling Pathway Diagram
 Oxytocin Signaling Pathway antibodies  Oxytocin Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >4 publications with CAMK1 and Disease Models, Animal
 Hypertension Antibodies  >4 publications with CAMK1 and Hypertension
 Hypertrophy Antibodies  >3 publications with CAMK1 and Hypertrophy
 Kidney Diseases Antibodies  >3 publications with CAMK1 and Kidney Diseases
 Fibrosis Antibodies  >2 publications with CAMK1 and Fibrosis
 Carcinoma, Hepatocellular Antibodies  >1 publications with CAMK1 and Carcinoma, Hepatocellular
 Neoplasms, Experimental Antibodies  >1 publications with CAMK1 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >1 publications with CAMK1 and Liver Neoplasms
 Hyperplasia Antibodies  >1 publications with CAMK1 and Hyperplasia
 Liver Diseases Antibodies  >1 publications with CAMK1 and Liver Diseases
Organs/Tissues associated with CAMK1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >43 publications with CAMK1 and Brain
 Muscle Antibodies  >11 publications with CAMK1 and Muscle
 Heart Antibodies  >9 publications with CAMK1 and Heart
 Liver Antibodies  >5 publications with CAMK1 and Liver
 Adrenal Gland Antibodies  >5 publications with CAMK1 and Adrenal Gland
 Testis Antibodies  >4 publications with CAMK1 and Testis
 Eye Antibodies  >3 publications with CAMK1 and Eye
 Kidney Antibodies  >3 publications with CAMK1 and Kidney
 Ganglia Antibodies  >3 publications with CAMK1 and Ganglia
 Bone Antibodies  >3 publications with CAMK1 and Bone
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