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Camk2a recombinant protein :: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Camk2a) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS964219 Camk2a recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $900 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,110 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,200 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,325 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,325 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,360 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,410 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,500 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,885 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,020 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,050 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,280 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,655 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Camk2a), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Calcium/calmodulin-dependent protein kinase type II subunit alpha (Camk2a)

 Product Gene Name   

Camk2a recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-478aa, Full length protein
 Sequence    MATITCTRFT EEYQLFEELG KGAFSVVRRC VKVLAGQEYA AKIINTKKLS ARDHQKLERE ARICRLLKHP NIVRLHDSIS EEGHHYLIFD LVTGGELFED IVAREYYSEA DASHCIQQIL EAVLHCHQMG VVHRDLKPEN LLLASKLKGA AVKLADFGLA IEVEGEQQAW FGFAGTPGYL SPEVLRKDPY GKPVDLWACG VILYILLVGY PPFWDEDQHR LYQQIKAGAY DFPSPEWDTV TPEAKDLINK MLTINPSKRI TAAEALKHPW ISHRSTVASC MHRQETVDCL KKFNARRKLK GAILTTMLAT RNFSGGKSGG NKKNDGVKES SESTNTTIED EDTKVRKQEI IKVTEQLIEA ISNGDFESYT KMCDPGMTAF EPEALGNLVE GLDFHRFYFE NLWSRNSKPV HTTILNPHIH LMGDESACIA YIRITQYLDA GGIPRTAQSE ETRVWHRRDG KWQIVHFHRS GAPSVLPH
 3D Structure    ModBase 3D Structure for P11798
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Camk2a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Camk2a recombinant protein

   The product of this gene belongs to the serine
threonine protein kinases family, and to the Ca(2+)
calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
NCBI/Uniprot data below describe general gene information for Camk2a. It may not necessarily be applicable to this product.
 NCBI GI #    558472775
 NCBI GeneID    12322
 NCBI Accession #    NP_001273738.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001286809.1 [Other Products]
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 UniProt Primary Accession #    P11798 [Other Products]
 UniProt Secondary Accession #    Q61284; Q6ZWN4 [Other Products]
 UniProt Related Accession #    P11798 [Other Products]
 Molecular Weight    22,584 Da
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 NCBI Official Full Name    calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 3
 NCBI Official Synonym Full Names    calcium/calmodulin-dependent protein kinase II alpha
 NCBI Official Symbol    Camk2a [Similar Products]
 NCBI Official Synonym Symbols   
CaMKII; R74975; mKIAA0968
[Similar Products]
 NCBI Protein Information    calcium/calmodulin-dependent protein kinase type II subunit alpha
 UniProt Protein Name    Calcium/calmodulin-dependent protein kinase type II subunit alpha
 Protein Family    Calcium/calmodulin-dependent protein kinase
 UniProt Gene Name    Camk2a [Similar Products]
 UniProt Synonym Gene Names    CaM kinase II subunit alpha; CaMK-II subunit alpha [Similar Products]
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 UniProt Comments for Camk2a    CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. Phosphorylates transcription factor FOXO3 on 'Ser-298' (). Activates FOXO3 transcriptional activity (PubMed:23805378).
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 Research Articles on Camk2a    1. Data suggest that alphaCaMKII autophosphorylation-dependent remodeling of glutamatergic synapses is a plausible mechanism for the regulation of the alcohol addiction-related behaviors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Camk2a recombinant proteinDiseases associated with Camk2a recombinant protein
 Products by Pathway  Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Cholinergic Synapse Pathway antibodies  Cholinergic Synapse Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >36 publications with Camk2a and Nervous System Diseases
 Brain Diseases Antibodies  >23 publications with Camk2a and Brain Diseases
 Cardiovascular Diseases Antibodies  >11 publications with Camk2a and Cardiovascular Diseases
 Vascular Diseases Antibodies  >10 publications with Camk2a and Vascular Diseases
 Cerebrovascular Disorders Antibodies  >9 publications with Camk2a and Cerebrovascular Disorders
 Pain Antibodies  >7 publications with Camk2a and Pain
 Drug Toxicity Antibodies  >7 publications with Camk2a and Drug Toxicity
 Seizures Antibodies  >5 publications with Camk2a and Seizures
 Cognition Disorders Antibodies  >4 publications with Camk2a and Cognition Disorders
 Memory Disorders Antibodies  >4 publications with Camk2a and Memory Disorders
Organs/Tissues associated with Camk2a recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >4 publications with Camk2a and Muscle
 Eye Antibodies  >4 publications with Camk2a and Eye
 Embryonic Tissue Antibodies  >3 publications with Camk2a and Embryonic Tissue
 Spleen Antibodies  >1 publications with Camk2a and Spleen
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