Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow CASQ1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Interleukin-13 protein (IL13) Recombinant Protein
 • SPIN2B Antibody
 • Occludin (OCLN) ELISA Kit
 • FOSL1 Antibody
 • Clara cell Specific protein CC16 ELISA Kit
 • Tumor Fibrin and Fibrinogen Degradation Products (tFFDP) ELISA Kit
 • Ras-related protein Rab-1A (RAB1A) Antibody
 • lipase A, lysosomal acid, cholesterol esterase ELISA Kit
 • NME2 Antibody
 • (E)-beta-farnesene synthase, partial Recombinant Protein
 • IL-1 beta (IL1B) ELISA Kit
 • Clara Cell Protein 16 (CC16) ELISA Kit
 • Serum, Feline (SAA1) Antibody
 • neurotrimin (NTM) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

CASQ1 recombinant protein :: Calsequestrin-1 (CASQ1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS961847 CASQ1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $775 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,020 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,035 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,140 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,195 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,265 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,290 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,350 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,620 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,860 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,920 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,050 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,470 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Calsequestrin-1 (CASQ1), Recombinant Protein

 Also Known As   

Recombinant Human Calsequestrin-1 (CASQ1)

 Product Gene Name   

CASQ1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    35-396aa, Full Length of Mature Protein
 Sequence    QEGLDFPEYD GVDRVINVNA KNYKNVFKKY EVLALLYHEP PEDDKASQRQ FEMEELILEL AAQVLEDKGV GFGLVDSEKD AAVAKKLGLT EVDSMYVFKG DEVIEYDGEF SADTIVEFLL DVLEDPVELI EGERELQAFE NIEDEIKLIG YFKSKDSEHY KAFEDAAEEF HPYIPFFATF DSKVAKKLTL KLNEIDFYEA FMEEPVTIPD KPNSEEEIVN FVEEHRRSTL RKLKPESMYE TWEDDMDGIH IVAFAEEADP DGFEFLETLK AVAQDNTENP DLSIIWIDPD DFPLLVPYWE KTFDIDLSAP QIGVVNVTDA DSVWMEMDDE EDLPSAEELE DWLEDVLEGE INTEDDDDDD DD
 OMIM    114250
 3D Structure    ModBase 3D Structure for P31415
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
Section Bar
 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CASQ1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for CASQ1 recombinant protein

   This protein is a mitochondrial calcium-binding protein located in the luminal space of the terminal cisternae of the sarcoplasmic reticulum. The protein binds and putatively stores calcium ions. The protein is absent in patients with Duchenne and Becker types of muscular dystrophy.
NCBI/Uniprot data below describe general gene information for CASQ1. It may not necessarily be applicable to this product.
 NCBI GI #    227430327
 NCBI GeneID    844
 NCBI Accession #    NP_001222.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_001231.4 [Other Products]
Section Bar
 UniProt Primary Accession #    P31415 [Other Products]
 UniProt Secondary Accession #    Q8TBW7; B1AKZ2; B2R863 [Other Products]
 UniProt Related Accession #    P31415 [Other Products]
 Molecular Weight    45,160 Da
Table BarTOPTable Bar
 NCBI Official Full Name    calsequestrin-1
 NCBI Official Synonym Full Names    calsequestrin 1
 NCBI Official Symbol    CASQ1 [Similar Products]
 NCBI Official Synonym Symbols   
CASQ; PDIB1; VMCQA
[Similar Products]
 NCBI Protein Information    calsequestrin-1
 UniProt Protein Name    Calsequestrin-1
 UniProt Synonym Protein Names   
Calmitine
 Protein Family    Calsequestrin
 UniProt Gene Name    CASQ1 [Similar Products]
 UniProt Synonym Gene Names    CASQ [Similar Products]
Section Bar
 NCBI Summary for CASQ1    This gene encodes the skeletal muscle specific member of the calsequestrin protein family. Calsequestrin functions as a luminal sarcoplasmic reticulum calcium sensor in both cardiac and skeletal muscle cells. This protein, also known as calmitine, functions as a calcium regulator in the mitochondria of skeletal muscle. This protein is absent in patients with Duchenne and Becker types of muscular dystrophy. [provided by RefSeq, Jun 2013]
Section Bar
 UniProt Comments for CASQ1    Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle (PubMed:28895244). Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca2+ ions (PubMed:28895244). Regulates the release of lumenal Ca2+ via the calcium release channel RYR1; this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca2+ entry (SOCE) activity (PubMed:27185316).
Table BarTOPTable Bar
 Research Articles on CASQ1    1. the p.D244G variant in CASQ1 is associated with a skeletal muscle disease and alters sarcoplasmic calcium release
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with CASQ1 recombinant proteinPathways associated with CASQ1 recombinant protein
 Reference Product  PubMed Publications
 RYR2 recombinant protein  >17 publications with CASQ1 and RYR2
 RYR1 recombinant protein  >16 publications with CASQ1 and RYR1
 CACNA1S recombinant protein  >4 publications with CASQ1 and CACNA1S
 ATP2A1 recombinant protein  >2 publications with CASQ1 and ATP2A1
 TRDN recombinant protein  >2 publications with CASQ1 and TRDN
 PLN recombinant protein  >1 publications with CASQ1 and PLN
 ASPH recombinant protein  >1 publications with CASQ1 and ASPH
 Products by Pathway  Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
Diseases associated with CASQ1 recombinant proteinOrgans/Tissues associated with CASQ1 recombinant protein
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >3 publications with CASQ1 and Necrosis
 Congenital Abnormalities Antibodies  >1 publications with CASQ1 and Congenital Abnormalities
 Lung Neoplasms Antibodies  >1 publications with CASQ1 and Lung Neoplasms
 Nervous System Malformations Antibodies  >1 publications with CASQ1 and Nervous System Malformations
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >66 publications with CASQ1 and Muscle
 Heart Antibodies  >12 publications with CASQ1 and Heart
 Eye Antibodies  >5 publications with CASQ1 and Eye
 Brain Antibodies  >3 publications with CASQ1 and Brain
 Placenta Antibodies  >1 publications with CASQ1 and Placenta
 Liver Antibodies  >1 publications with CASQ1 and Liver
 Prostate Antibodies  >1 publications with CASQ1 and Prostate
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions