Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow CA2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Plasmodium falciparum Antibody
 • phosphofurin acidic cluster sorting protein 2 (pacs2) Antibody
 • S100 calcium-binding protein A8-A9 complex (S100A8-A9) Elisa... ELISA Kit
 • dipeptidyl-peptidase 4 (DPP4) ELISA Kit
 • Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit
 • Monosialoganglioside GM4 Ganglioside
 • MT-ND2 Antibody
 • Measles IgM ELISA Kit
 • Thyroid Stimulating Hormone (TSH) alpha Antibody
 • ORAI1-CRACM1 Antibody
 • G-CSF Active Protein
 • Leishmania donovani KMP-11 Antigen
 • GRIN1 Antibody
 • AKAP, Muscle (AKAP1) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

CA2 recombinant protein :: Carbonic anhydrase 2 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS203326
SDS-Page
Unit / Price
0.1 mg  /  $375 +1 FREE 8GB USB
0.5 mg  /  $925 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Carbonic anhydrase 2 (CA2), Recombinant Protein

★Popular Item★
 Also Known As   

Carbonic anhydrase 2, 1-260aa, Human, E Coli (Bioactivity Validated)

 Product Synonym Names    Carbonic anhydrase 2; CA-II; CAC; CA 2; CA II; CA2; CAI; Car 2; Car2; Carbonate dehydratase II; Carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; Carbonic dehydratase.
 Product Gene Name   

CA2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    MSHHWGYGKH NGPEHWHKDF PIAKGERQSP VDIDTHTAKY DPSLKPLSVS YDQATSLRIL NNGHAFNVEF DDSQDKAVLK GGPLDGTYRL IQFHFHWGSL DGQGSEHTVD KKKYAAELHL VHWNTKYGDF GKAVQQPDGL AVLGIFLKVG SAKPGLQKVV DVLDSIKTKG KSADFTNFDP RGLLPESLDY WTYPGSLTTP PLLECVTWIV LKEPISVSSE QVLKFRKLNF NGEGEPEELM VDNWRPAQPL KNRQIKASFK
 OMIM    M77181
 3D Structure
   ModBase 3D Structure for P00918
Section Bar
 Host    E Coli
Section Bar
 Purity/Purification    > 95% by SDS-PAGE
 Form/Format    Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 50mM NaCl, 10% glycerol
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
Section Bar
 Antigen Species    Human
 Biological Activity    Specific activity is > 7,000 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1.0 pmole of 4-nitrophenyl acetate to 4-nitrophenol per minute at pH 8.0 at 37C.
Section Bar
 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of CA2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for CA2 recombinant protein

   Carbonic anhydrase 2 (CA2) is one of fourteen forms of human alpha carbonic anhydrases. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. CA2 is a cytosolic enzyme with the highest activity among all known CAs. Mutations in the CA2 gene result in the CA2 deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis and cerebral calcification. Recombinant human CA2 was expressed in E Coli and purified by using conventional chromatography.
 Product Categories/Family for CA2 recombinant protein    Enzymes & Proteases
 Applications Tested/Suitable for CA2 recombinant protein   

SDS-PAGE

Section Bar
 SDS-Page of CA2 recombinant protein    CA2 recombinant protein SDS-Page image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CA2. It may not necessarily be applicable to this product.
 NCBI GI #    4557395
 NCBI GeneID    760
 NCBI Accession #    NP_000058 [Other Products]
 NCBI GenBank Nucleotide #    NM_000067.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P00918 [Other Products]
 UniProt Secondary Accession #    Q6FI12; Q96ET9; B2R7G8 [Other Products]
 UniProt Related Accession #    P00918 [Other Products]
 Molecular Weight    29.2 kDa (260aa), confirmed by MALDI-TOF. [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    carbonic anhydrase 2 isoform 1
 NCBI Official Synonym Full Names    carbonic anhydrase 2
 NCBI Official Symbol    CA2 [Similar Products]
 NCBI Official Synonym Symbols   
CAC; CAII; Car2; CA-II; HEL-76; HEL-S-282
[Similar Products]
 NCBI Protein Information    carbonic anhydrase 2
 UniProt Protein Name    Carbonic anhydrase 2
 UniProt Synonym Protein Names   
Carbonate dehydratase II; Carbonic anhydrase C; CAC; Carbonic anhydrase II; CA-II
 Protein Family    Carbonic anhydrase
 UniProt Gene Name    CA2 [Similar Products]
 UniProt Synonym Gene Names    CAC; CA-II [Similar Products]
Section Bar
 NCBI Summary for CA2    The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Section Bar
 UniProt Comments for CA2    Essential for bone resorption and osteoclast differentiation (). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.
Table BarTOPTable Bar
 

Product References and Citations for CA2 recombinant protein

   Hu PY., et al. (1992). Hum Mutat. 1 (4):288-92 ; Venta PJ., et al. (1991). Am J Hum Genet. 49 (5):1082-90;
Section Bar
 Research Articles on CA2    1. These six-membered carbocycles showed nice inhibitory action against AChE and human carbonic anhydrase (hCA) II and I isoforms. The hCA I, II, and AChE were efficiently inhibited by these molecules, with Ki values in the range of 6.70-35.85 nM for hCA I, 18.77-60.84 nM for hCA II, and 0.74-4.60 for AChE, respectively
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with CA2 recombinant proteinPathways associated with CA2 recombinant protein
 Reference Product  PubMed Publications
 SLC9A1 recombinant protein  >30 publications with CA2 and SLC9A1
 ALB recombinant protein  >16 publications with CA2 and ALB
 SLC4A4 recombinant protein  >6 publications with CA2 and SLC4A4
 CALM1 recombinant protein  >5 publications with CA2 and CALM1
 SLC4A2 recombinant protein  >1 publications with CA2 and SLC4A2
 CALM3 recombinant protein  >1 publications with CA2 and CALM3
 CALM2 recombinant protein  >1 publications with CA2 and CALM2
 Products by Pathway  Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Collecting Duct Acid Secretion Pathway antibodies  Collecting Duct Acid Secretion Pathway Diagram
 Collecting Duct Acid Secretion Pathway antibodies  Collecting Duct Acid Secretion Pathway Diagram
 Erythrocytes Take Up Carbon Dioxide And Release Oxygen Pathway antibodies  Erythrocytes Take Up Carbon Dioxide And Release Oxygen Pathway Diagram
 Erythrocytes Take Up Oxygen And Release Carbon Dioxide Pathway antibodies  Erythrocytes Take Up Oxygen And Release Carbon Dioxide Pathway Diagram
 Gastric Acid Secretion Pathway antibodies  Gastric Acid Secretion Pathway Diagram
 Gastric Acid Secretion Pathway antibodies  Gastric Acid Secretion Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Nitrogen Metabolism Pathway antibodies  Nitrogen Metabolism Pathway Diagram
Diseases associated with CA2 recombinant proteinOrgans/Tissues associated with CA2 recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >7271 publications with CA2 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >4889 publications with CA2 and Nervous System Diseases
 Heart Diseases Antibodies  >4397 publications with CA2 and Heart Diseases
 Disease Models, Animal Antibodies  >2564 publications with CA2 and Disease Models, Animal
 Hypertension Antibodies  >2422 publications with CA2 and Hypertension
 Inflammation Antibodies  >1532 publications with CA2 and Inflammation
 Necrosis Antibodies  >1479 publications with CA2 and Necrosis
 Hypertrophy Antibodies  >1285 publications with CA2 and Hypertrophy
 Kidney Diseases Antibodies  >837 publications with CA2 and Kidney Diseases
 Neoplasms, Experimental Antibodies  >790 publications with CA2 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >21069 publications with CA2 and Brain
 Blood Antibodies  >17900 publications with CA2 and Blood
 Heart Antibodies  >15175 publications with CA2 and Heart
 Liver Antibodies  >5031 publications with CA2 and Liver
 Kidney Antibodies  >4596 publications with CA2 and Kidney
 Pancreas Antibodies  >3317 publications with CA2 and Pancreas
 Intestine Antibodies  >2573 publications with CA2 and Intestine
 Eye Antibodies  >2544 publications with CA2 and Eye
 Lung Antibodies  >2185 publications with CA2 and Lung
 Embryonic Tissue Antibodies  >1777 publications with CA2 and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions