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CT1 recombinant protein :: Cardiotrophin 1 (CT1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2011337 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) CT1 recombinant protein
Unit / Price
0.01 mg  /  $150 +1 FREE 8GB USB
0.05 mg  /  $290 +1 FREE 8GB USB
0.1 mg  /  $455 +1 FREE 8GB USB
0.2 mg  /  $560 +1 FREE 8GB USB
0.5 mg  /  $1,080 +1 FREE 8GB USB
1 mg  /  $1,610 +2 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cardiotrophin 1 (CT1), Recombinant Protein

 Also Known As   

Recombinant Cardiotrophin 1 (CT1)

 Product Gene Name   

CT1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with one N-terminal His-tag, its sequence is listed below.
 Chromosome Location    Chromosome: 16; NC_000016.9 (30907928..30914881). Location: 16p11.2
 OMIM    600435
 3D Structure    ModBase 3D Structure for Q16619
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
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 Organism    Homo sapiens (Human)
 Expression System    Prokaryotic expression
 Residues    Met1~Ala201 (Accession # Q16619) with one N-terminal His-tag
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of CT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CT1 recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for CT1 recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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NCBI/Uniprot data below describe general gene information for CT1. It may not necessarily be applicable to this product.
 NCBI GI #    216548056
 NCBI GeneID    1489
 NCBI Accession #    NP_001136016.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001142544.1 [Other Products]
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 UniProt Primary Accession #    Q16619 [Other Products]
 UniProt Secondary Accession #    Q5U5Y7; A8MVX4 [Other Products]
 UniProt Related Accession #    Q16619 [Other Products]
 Molecular Weight    22.7kDa
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 NCBI Official Full Name    cardiotrophin-1 isoform 2
 NCBI Official Synonym Full Names    cardiotrophin 1
 NCBI Official Symbol    CTF1 [Similar Products]
 NCBI Official Synonym Symbols   
CT1; CT-1
[Similar Products]
 NCBI Protein Information    cardiotrophin-1; cardiophin 1
 UniProt Protein Name    Cardiotrophin-1
 UniProt Gene Name    CTF1 [Similar Products]
 UniProt Synonym Gene Names    CT-1 [Similar Products]
 UniProt Entry Name    CTF1_HUMAN
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 NCBI Summary for CT1    The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
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 UniProt Comments for CT1    CTF1: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: extracellular space; extracellular region

Molecular Function: leukemia inhibitory factor receptor binding; cytokine activity

Biological Process: cell proliferation; nervous system development; muscle development; cell-cell signaling; leukemia inhibitory factor signaling pathway; positive regulation of cell proliferation; neuron development
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 Research Articles on CT1    1. Cardiotrophin-1 may serve as both a biomarker of left ventricular hypertrophy and dysfunction in hypertensive patients, and is potential target for therapies aimed to prevent and treat hypertensive heart disease beyond blood pressure control.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CT1 recombinant proteinDiseases associated with CT1 recombinant protein
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 MicroRNAs In Cardiomyocyte Hypertrophy Pathway antibodies  MicroRNAs In Cardiomyocyte Hypertrophy Pathway Diagram
 Physiological And Pathological Hypertrophy Of The Heart Pathway antibodies  Physiological And Pathological Hypertrophy Of The Heart Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >8 publications with CT1 and Neoplasms
 Neoplasms, Experimental Antibodies  >3 publications with CT1 and Neoplasms, Experimental
 Ischemia Antibodies  >1 publications with CT1 and Ischemia
 Hypertrophy Antibodies  >1 publications with CT1 and Hypertrophy
 Reperfusion Injury Antibodies  >1 publications with CT1 and Reperfusion Injury
 Acute Kidney Injury Antibodies  >1 publications with CT1 and Acute Kidney Injury
 Heart Diseases Antibodies  >1 publications with CT1 and Heart Diseases
 Inflammation Antibodies  >1 publications with CT1 and Inflammation
 Neovascularization, Pathologic Antibodies  >1 publications with CT1 and Neovascularization, Pathologic
 Necrosis Antibodies  >1 publications with CT1 and Necrosis
Organs/Tissues associated with CT1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with CT1 and Brain
 Nerve Antibodies  >1 publications with CT1 and Nerve
 Lung Antibodies  >1 publications with CT1 and Lung
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