Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow CT1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • ELOVL family member 5, elongation of long chain fatty acids ... ELISA Kit
 • EGF Recombinant Protein
 • Signal Transducer And Activator Of Transcription 2 (STAT2) ELISA Kit
 • basic fibroblast growth factor 4, bFGF-4 ELISA Kit
 • (3R)-hydroxymyristoyl-[acyl -carrier-protein] dehydratase (fa... Recombinant Protein
 • Tumor Necrosis Factor Receptor 2, p75-p80 (TNFRSF1B) Antibody
 • 15.7 kDa heat shock protein, peroxisomal (HSP15.7) Recombinant Protein
 • paraoxonase 2 (PON2) ELISA Kit
 • 3-hydroxy-3-methylglutaryl- coenzyme A reductase (HMGCR-HMG-C... ELISA Kit
 • Mu Opioid Receptor (OPRM1) Antibody
 • CKI-epsilon Antibody
 • F-box only protein 22 (Fbxo22) Recombinant Protein
 • HDDC3 Antibody
 • ROBO3 - RIG1 Peptide
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

CT1 recombinant protein :: Cardiotrophin 1 (CT1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2011337 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) CT1 recombinant protein
Unit / Price
0.01 mg  /  $200 +1 FREE 8GB USB
0.05 mg  /  $430 +1 FREE 8GB USB
0.1 mg  /  $665 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cardiotrophin 1 (CT1), Recombinant Protein

 Also Known As   

Recombinant Cardiotrophin 1 (CT1)

 Product Gene Name   

CT1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    The target protein is fused with one N-terminal His-tag, its sequence is listed below.
MGHHHHHHSG SEF MSRREGSLED PQTDSSVSLL PHLEAKIRQT HSLAHLLTKY AEQLLQEYVQ LQGDPFGLPS FSPPRLPVAG LSAPAPSHAG LPVHERLRLD AAALAALPPL LDAVCRRQAE LNPRAPRLLR RLEDAARQAR ALGAAVEALL AALGAANRGP RAEPPAATAS AASATGVFPA KVLGLRVCGL YREWLSRTEG DLGQLLPGGS A
 Chromosome Location    Chromosome: 16; NC_000016.9 (30907928..30914881). Location: 16p11.2
 OMIM    600435
 3D Structure    ModBase 3D Structure for Q16619
Section Bar
 Host    E Coli
Section Bar
 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Section Bar
 Organism    Homo sapiens (Human)
 Expression System    Prokaryotic expression
 Residues    Met1~Ala201 (Accession # Q16619) with one N-terminal His-tag
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
Section Bar
 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of CT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for CT1 recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for CT1 recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CT1. It may not necessarily be applicable to this product.
 NCBI GI #    216548056
 NCBI GeneID    1489
 NCBI Accession #    NP_001136016.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001142544.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q16619 [Other Products]
 UniProt Secondary Accession #    Q5U5Y7; A8MVX4 [Other Products]
 UniProt Related Accession #    Q16619 [Other Products]
 Molecular Weight    22.7kDa
Table BarTOPTable Bar
 NCBI Official Full Name    cardiotrophin-1 isoform 2
 NCBI Official Synonym Full Names    cardiotrophin 1
 NCBI Official Symbol    CTF1 [Similar Products]
 NCBI Official Synonym Symbols   
CT1; CT-1
[Similar Products]
 NCBI Protein Information    cardiotrophin-1; cardiophin 1
 UniProt Protein Name    Cardiotrophin-1
 UniProt Gene Name    CTF1 [Similar Products]
 UniProt Synonym Gene Names    CT-1 [Similar Products]
 UniProt Entry Name    CTF1_HUMAN
Section Bar
 NCBI Summary for CT1    The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Section Bar
 UniProt Comments for CT1    CTF1: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: extracellular space; extracellular region

Molecular Function: leukemia inhibitory factor receptor binding; cytokine activity

Biological Process: cell proliferation; nervous system development; muscle development; cell-cell signaling; leukemia inhibitory factor signaling pathway; positive regulation of cell proliferation; neuron development
Table BarTOPTable Bar
 Research Articles on CT1    1. Cardiotrophin-1 may serve as both a biomarker of left ventricular hypertrophy and dysfunction in hypertensive patients, and is potential target for therapies aimed to prevent and treat hypertensive heart disease beyond blood pressure control.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with CT1 recombinant proteinDiseases associated with CT1 recombinant protein
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 MicroRNAs In Cardiomyocyte Hypertrophy Pathway antibodies  MicroRNAs In Cardiomyocyte Hypertrophy Pathway Diagram
 Physiological And Pathological Hypertrophy Of The Heart Pathway antibodies  Physiological And Pathological Hypertrophy Of The Heart Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >8 publications with CT1 and Neoplasms
 Neoplasms, Experimental Antibodies  >3 publications with CT1 and Neoplasms, Experimental
 Ischemia Antibodies  >1 publications with CT1 and Ischemia
 Hypertrophy Antibodies  >1 publications with CT1 and Hypertrophy
 Reperfusion Injury Antibodies  >1 publications with CT1 and Reperfusion Injury
 Acute Kidney Injury Antibodies  >1 publications with CT1 and Acute Kidney Injury
 Heart Diseases Antibodies  >1 publications with CT1 and Heart Diseases
 Inflammation Antibodies  >1 publications with CT1 and Inflammation
 Neovascularization, Pathologic Antibodies  >1 publications with CT1 and Neovascularization, Pathologic
 Necrosis Antibodies  >1 publications with CT1 and Necrosis
Organs/Tissues associated with CT1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with CT1 and Brain
 Nerve Antibodies  >1 publications with CT1 and Nerve
 Lung Antibodies  >1 publications with CT1 and Lung
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions