Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow Ctf1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • ERK1-2 (MAPK1) Antibody
 • antiplasmin (SERPINF2) Antibody
 • Amyloid Beta Peptide 1-42 (Ab1-42) Antibody
 • M-5 Muscarinic receptor Antibody
 • IL6R alpha Recombinant Protein
 • Complement Component 3a (C3a) Recombinant Protein
 • Cytochrome P450 2A6 (CYP2A6) ELISA Kit
 • GRObeta ELISA Kit
 • Interleukin-8 (IL-8) Western Blot Control
 • Hepatitis B 'e' Antigen (HBeAg) Antibody
 • peptidylprolyl isomerase D (PPID) ELISA Kit
 • Neuron-specific enolase (NSE) Antigen
 • SMARCD3 Antibody
 • NGF cDNA Clone
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

Ctf1 recombinant protein :: Cardiotrophin-1 protein (Ctf1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS969139
SDS-PAGE
Unit / Price
0.002 mg  /  $115 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
0.1 mg  /  $720 +1 FREE 8GB USB
0.25 mg  /  $1,230 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cardiotrophin-1 protein (Ctf1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rat Cardiotrophin-1 protein (Ctf1) (Active)

 Product Synonym Names    CT-1
 Product Gene Name   

Ctf1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    1-203aa, Full Length
 Sequence    MSQREGSLED HQTDSSFSFL PHLEAKIRQT HNLARLLTKY ADQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSALPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP VPEPVATSAL FTSNSAAGVF SAKVLGLHVC GLYGEWVSRT EGDLGQLVPG GVA
 3D Structure    ModBase 3D Structure for Q63086
Section Bar
 Host    E Coli
Section Bar
 Purity/Purification    >=95% as determined by SDS-PAGE and HPLC. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Rattus norvegicus (Rat)
 Biological Activity    Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.5 ng/ml, corresponding to a specific activity of > 2.0 106 IU/mg.
 Storage Buffer    0.2 um filtered 20 mM PB, pH 7.4, 150mM NaCl,lyophilized
 Endotoxin    Less than 1.0 EU/ug as determined by LAL method.
Section Bar
 Preparation and Storage    Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Ctf1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for Ctf1 recombinant protein

   Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
 Product Categories/Family for Ctf1 recombinant protein    Biological Active Protein; Immunology
Section Bar
 SDS-PAGE of Ctf1 recombinant protein    Ctf1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for Ctf1. It may not necessarily be applicable to this product.
 NCBI GI #    8393212
 NCBI GeneID    29201
 NCBI Accession #    NP_058825.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_017129.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q63086 [Other Products]
 UniProt Related Accession #    Q63086 [Other Products]
 Molecular Weight    21.4 kDa
Table BarTOPTable Bar
 NCBI Official Full Name    cardiotrophin-1
 NCBI Official Synonym Full Names    cardiotrophin 1
 NCBI Official Symbol    Ctf1 [Similar Products]
 NCBI Protein Information    cardiotrophin-1
 UniProt Protein Name    Cardiotrophin-1
 Protein Family    Cardiotrophin
 UniProt Gene Name    Ctf1 [Similar Products]
 UniProt Synonym Gene Names    CT-1 [Similar Products]
Section Bar
 NCBI Summary for Ctf1    Interleukin-6 family cytokine with hypertrophic and protective effects in cardiac cells; also a neurotrophic factor [RGD, Feb 2006]
Section Bar
 UniProt Comments for Ctf1    CTF1: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 1q37

Cellular Component: extracellular region

Molecular Function: cytokine activity; leukemia inhibitory factor receptor binding

Biological Process: leukemia inhibitory factor signaling pathway; nervous system development; neuron development; positive regulation of tyrosine phosphorylation of STAT protein
Table BarTOPTable Bar
 Research Articles on Ctf1    1. In the chronic kidney disease-cardiac hypertrophy model exercise rescues cardiac disease via cardiotrophin-1/LIFR/gp 130/JAK/STAT3 pathway.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with Ctf1 recombinant proteinPathways associated with Ctf1 recombinant protein
 Reference Product  PubMed Publications
 Lif recombinant protein  >2 publications with Ctf1 and Lif
 Osm recombinant protein  >1 publications with Ctf1 and Osm
 Il6 recombinant protein  >1 publications with Ctf1 and Il6
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 IL-6-type Cytokine Receptor Ligand Interactions Pathway antibodies  IL-6-type Cytokine Receptor Ligand Interactions Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interleukin-6 Family Signaling Pathway antibodies  Interleukin-6 Family Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Signaling By Interleukins Pathway antibodies  Signaling By Interleukins Pathway Diagram
Diseases associated with Ctf1 recombinant proteinOrgans/Tissues associated with Ctf1 recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >3 publications with Ctf1 and Cardiovascular Diseases
 Neoplasm Invasiveness Antibodies  >1 publications with Ctf1 and Neoplasm Invasiveness
 Acute Kidney Injury Antibodies  >1 publications with Ctf1 and Acute Kidney Injury
 Anoxia Antibodies  >1 publications with Ctf1 and Anoxia
 Memory Disorders Antibodies  >1 publications with Ctf1 and Memory Disorders
 Heart Diseases Antibodies  >1 publications with Ctf1 and Heart Diseases
 Inflammation Antibodies  >1 publications with Ctf1 and Inflammation
 Necrosis Antibodies  >1 publications with Ctf1 and Necrosis
 Cardiomyopathies Antibodies  >1 publications with Ctf1 and Cardiomyopathies
 Hypertrophy Antibodies  >1 publications with Ctf1 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >5 publications with Ctf1 and Heart
 Lung Antibodies  >1 publications with Ctf1 and Lung
 Embryonic Tissue Antibodies  >1 publications with Ctf1 and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions