View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List CTF1 recombinant protein :: Cardiotrophin-1 Recombinant Protein Catalog # MBS546299 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Cardiotrophin-1 (CTF1), Recombinant Protein Full Product Name Cardiotrophin-1, rat Product Gene Name CTF1 recombinant protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 600435 Other Notes Small volumes of CTF1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP NCBI/Uniprot data below describe general gene information for CTF1. It may not necessarily be applicable to this product. NCBI GI # 216548056 NCBI GeneID 1489 NCBI Accession # NP_001136016.1 [Other Products] NCBI GenBank Nucleotide # NM_001142544.1 [Other Products] UniProt Secondary Accession # Q5U5Y7; A8MVX4[Other Products] UniProt Related Accession # Q16619[Other Products] Molecular Weight 21,098 Da[Similar Products] TOP NCBI Official Full Name cardiotrophin-1 isoform 2 NCBI Official Synonym Full Names cardiotrophin 1 NCBI Official Symbol CTF1 [Similar Products] NCBI Official Synonym Symbols CT1; CT-1 [Similar Products] NCBI Protein Information cardiotrophin-1 UniProt Protein Name Cardiotrophin-1 Protein Family Cardiotrophin UniProt Gene Name CTF1 [Similar Products] UniProt Synonym Gene Names CT-1 [Similar Products] UniProt Entry Name CTF1_HUMAN TOP NCBI Summary for CTF1 The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] TOP UniProt Comments for CTF1 CTF1: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: CytokineChromosomal Location of Human Ortholog: 16p11.2Cellular Component: extracellular region; extracellular spaceMolecular Function: cytokine activity; leukemia inhibitory factor receptor binding; protein bindingBiological Process: cell proliferation; cell surface receptor linked signal transduction; cell-cell signaling; leukemia inhibitory factor signaling pathway; muscle development; nervous system development; neuron development; positive regulation of cell proliferation; positive regulation of tyrosine phosphorylation of Stat3 protein Research Articles on CTF1 1. Data show that cardiotrophin-1 is positively related to brachial-ankle pulse-wave velocity (baPWV) independent of traditional cardiometabolic risk factors for arterial stiffness. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Pathways associated with CTF1 recombinant protein Products by Pathway Pathway Diagram Cytokine Signaling In Immune System Pathway antibodies Cytokine Signaling In Immune System Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram IL-6-type Cytokine Receptor Ligand Interactions Pathway antibodies IL-6-type Cytokine Receptor Ligand Interactions Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Interleukin-6 Family Signaling Pathway antibodies Interleukin-6 Family Signaling Pathway Diagram Jak-STAT Signaling Pathway antibodies Jak-STAT Signaling Pathway Diagram Jak-STAT Signaling Pathway antibodies Jak-STAT Signaling Pathway Diagram MicroRNAs In Cardiomyocyte Hypertrophy Pathway antibodies MicroRNAs In Cardiomyocyte Hypertrophy Pathway Diagram Physiological And Pathological Hypertrophy Of The Heart Pathway antibodies Physiological And Pathological Hypertrophy Of The Heart Pathway Diagram Diseases associated with CTF1 recombinant protein Disease Name Pubmed Publications Cardiovascular Diseases Antibodies >3 publications with CTF1 and Cardiovascular Diseases Neoplasms, Experimental Antibodies >2 publications with CTF1 and Neoplasms, Experimental Neoplasm Invasiveness Antibodies >1 publications with CTF1 and Neoplasm Invasiveness Anoxia Antibodies >1 publications with CTF1 and Anoxia Memory Disorders Antibodies >1 publications with CTF1 and Memory Disorders Acute Kidney Injury Antibodies >1 publications with CTF1 and Acute Kidney Injury Heart Diseases Antibodies >1 publications with CTF1 and Heart Diseases Inflammation Antibodies >1 publications with CTF1 and Inflammation Necrosis Antibodies >1 publications with CTF1 and Necrosis Hypertrophy Antibodies >1 publications with CTF1 and Hypertrophy Organs/Tissues associated with CTF1 recombinant protein Organ/Tissue Name Pubmed Publications Brain Antibodies >4 publications with CTF1 and Brain Uterus Antibodies >1 publications with CTF1 and Uterus Nerve Antibodies >1 publications with CTF1 and Nerve Lung Antibodies >1 publications with CTF1 and Lung TOP © 2006-24 MyBioSource.com. 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