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CASP3 recombinant protein :: Caspase-3 (CASP3) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1400242 CASP3 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $885 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $885 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,110 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,110 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,300 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,300 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,755 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,755 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Caspase-3 (CASP3), Recombinant Protein

 Also Known As   

Recombinant Rabbit Caspase-3 (CASP3)

 Product Synonym Names    Caspase-3; CASP-3; EC=3.4.22.56; Apopain; Cysteine protease CPP32Cleaved into the following 2 chains:; 1. Caspase-3 subunit p17; 2. Caspase-3 subunit p12
 Product Gene Name   

CASP3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    29-175
 Sequence    SG KYLDNSYKMD YPEMGLCIII NNKNFHKNTG MSSRSGTDVN AANLGETFMN LKYEVRNKND LTREEIMELM YNVSKEDHSK RSSFICVILS HGDEGVIYGT NGPIELKKLT SFFRGDYCRS LTGKPKLFII QACRGTELDS GIETD
 3D Structure    ModBase 3D Structure for Q8MJC3
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Oryctolagus cuniculus (Rabbit)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CASP3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CASP3. It may not necessarily be applicable to this product.
 NCBI GI #    126723382
 NCBI GeneID    100008840
 NCBI Accession #    NP_001075586.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001082117.1 [Other Products]
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 UniProt Primary Accession #    Q8MJC3 [Other Products]
 UniProt Related Accession #    Q8MJC3 [Other Products]
 Molecular Weight    31,653 Da
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 NCBI Official Full Name    caspase-3
 NCBI Official Symbol    CASP3 [Similar Products]
 NCBI Protein Information    caspase-3; CASP-3; apopain; cysteine protease CPP32
 UniProt Protein Name    Caspase-3
 UniProt Synonym Protein Names   
Apopain; Cysteine protease CPP32Cleaved into the following 2 chains:Caspase-3 subunit p17; Caspase-3 subunit p12
 Protein Family    Caspase
 UniProt Gene Name    CASP3 [Similar Products]
 UniProt Synonym Gene Names    CASP-3 [Similar Products]
 UniProt Entry Name    CASP3_RABIT
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 UniProt Comments for CASP3    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage ().
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 Research Articles on CASP3    1. This study revealed that the 810-nm low-level laser can improve cartilage structure, prevent articular cartilage degradation and significantly decrease the expression of caspase-3 in this surgery-induced osteoarthritis model.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CASP3 recombinant proteinPathways associated with CASP3 recombinant protein
 Reference Product  PubMed Publications
 XIAP recombinant protein  >829 publications with CASP3 and XIAP
 FADD recombinant protein  >607 publications with CASP3 and FADD
 FASLG recombinant protein  >388 publications with CASP3 and FASLG
 DIABLO recombinant protein  >333 publications with CASP3 and DIABLO
 APAF1 recombinant protein  >297 publications with CASP3 and APAF1
 SRC recombinant protein  >241 publications with CASP3 and SRC
 BIRC3 recombinant protein  >38 publications with CASP3 and BIRC3
 BIRC2 recombinant protein  >32 publications with CASP3 and BIRC2
 BCL2L11 recombinant protein  >7 publications with CASP3 and BCL2L11
 CYCS recombinant protein  >2 publications with CASP3 and CYCS
 Products by Pathway  Pathway Diagram
 Activation Of DNA Fragmentation Factor Pathway antibodies  Activation Of DNA Fragmentation Factor Pathway Diagram
 Activation Of Caspases Through Apoptosome-mediated Cleavage Pathway antibodies  Activation Of Caspases Through Apoptosome-mediated Cleavage Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
Diseases associated with CASP3 recombinant proteinOrgans/Tissues associated with CASP3 recombinant protein
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >5297 publications with CASP3 and Necrosis
 Nervous System Diseases Antibodies  >3884 publications with CASP3 and Nervous System Diseases
 Inflammation Antibodies  >2341 publications with CASP3 and Inflammation
 Liver Diseases Antibodies  >1640 publications with CASP3 and Liver Diseases
 Brain Ischemia Antibodies  >1234 publications with CASP3 and Brain Ischemia
 Heart Diseases Antibodies  >1140 publications with CASP3 and Heart Diseases
 Neoplasms, Experimental Antibodies  >1057 publications with CASP3 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >1044 publications with CASP3 and Breast Neoplasms
 Kidney Diseases Antibodies  >617 publications with CASP3 and Kidney Diseases
 Nerve Degeneration Antibodies  >572 publications with CASP3 and Nerve Degeneration
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4544 publications with CASP3 and Blood
 Brain Antibodies  >4405 publications with CASP3 and Brain
 Liver Antibodies  >2229 publications with CASP3 and Liver
 Muscle Antibodies  >2000 publications with CASP3 and Muscle
 Vascular Antibodies  >1943 publications with CASP3 and Vascular
 Lung Antibodies  >1635 publications with CASP3 and Lung
 Heart Antibodies  >1590 publications with CASP3 and Heart
 Kidney Antibodies  >1121 publications with CASP3 and Kidney
 Bone Antibodies  >946 publications with CASP3 and Bone
 Prostate Antibodies  >768 publications with CASP3 and Prostate
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