NP_001012329.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
9,170 Da
NCBI Official Full Name
beta-catenin-interacting protein 1
NCBI Official Synonym Full Names
catenin, beta interacting protein 1
NCBI Official Synonym Symbols
NCBI Protein Information
beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; inhibitor of beta-catenin and Tcf-4
UniProt Protein Name
Beta-catenin-interacting protein 1
UniProt Synonym Protein Names
Inhibitor of beta-catenin and Tcf-4
UniProt Synonym Gene Names
UniProt Entry Name
CNBP1_HUMAN
NCBI Summary for CTNNBIP1
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for CTNNBIP1
CTNNBIP1: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. Belongs to the CTNNBIP1 family.
Protein type: Cell development/differentiation; Inhibitor
Chromosomal Location of Human Ortholog: 1p36.22
Cellular Component: nucleoplasm; cytoplasm; nucleus; beta-catenin destruction complex; cytosol
Molecular Function: protein binding; beta-catenin binding
Biological Process: anterior/posterior pattern formation; positive regulation of monocyte differentiation; positive regulation of osteoblast differentiation; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; ureteric bud branching; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; negative regulation of protein binding; regulation of vascular permeability during acute inflammatory response; negative regulation of DNA binding
Research Articles on CTNNBIP1
Precautions
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Products associated with CTNNBIP1 recombinant protein
Pathways associated with CTNNBIP1 recombinant protein
Diseases associated with CTNNBIP1 recombinant protein
Organs/Tissues associated with CTNNBIP1 recombinant protein
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