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CTNNBIP1 recombinant protein :: Catenin, Beta Interacting Protein 1 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS143957 CTNNBIP1 recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.025 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $2,235 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Catenin, Beta Interacting Protein 1 (CTNNBIP1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Catenin, Beta Interacting Protein 1

 Product Synonym Names    CTNNBIP1 Human; Catenin, Beta Interacting Protein 1 Human Recombinant; ICAT; MGC15093; CNBP1; CTNNBIP1; Beta-catenin-interacting protein 1; Inhibitor of beta-catenin and Tcf-4
 Product Gene Name   

CTNNBIP1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHH HHH SSGLVPRGSH MNREGAPGKS PEEMYIQQKV RVLLMLRKMG SNLTASEEEF LRTYAGVVNS QLSQLPPHSI DQGAEDVVMA FSRSETEDRR Q
 OMIM    607758
 3D Structure    ModBase 3D Structure for Q9NSA3
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 Host    E Coli
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 Purity/Purification    Greater than 90.0% as determined by SDS-PAGE.
 Form/Format    CTNNBIP1 Human solution containing 20mM Tris HCL pH-7.5, 2mM DTT, 0.1M NaCl & 20% glycerol.
Sterile filtered colorless solution.
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 Preparation and Storage    CTNNBIP1 Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
 Other Notes    Small volumes of CTNNBIP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CTNNBIP1 recombinant protein

   Description: CTNNBIP1 Recombinant E Coli produced in E Coli is a single, non-glycosylated polypeptide chain containing 101 amino acids (1-81 a.a.) and having a molecular mass of 11.3 kDa. The CTNNBIP1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Introduction: CTNNBIP1 binds CTNNB1 and avoids interaction between CTNNB1 and TCF (T-cell transcription factor) family members. CTNNBIP1 is a negative regulator of the Wnt signaling pathway.
 Product Categories/Family for CTNNBIP1 recombinant protein    RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
NCBI/Uniprot data below describe general gene information for CTNNBIP1. It may not necessarily be applicable to this product.
 NCBI GI #    59889555
 NCBI GeneID    56998
 NCBI Accession #    NP_001012329.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001012329.1 [Other Products]
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 UniProt Primary Accession #    Q9NSA3 [Other Products]
 UniProt Secondary Accession #    Q5T4V2 [Other Products]
 UniProt Related Accession #    Q9NSA3 [Other Products]
 Molecular Weight    9,170 Da
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 NCBI Official Full Name    beta-catenin-interacting protein 1
 NCBI Official Synonym Full Names    catenin, beta interacting protein 1
 NCBI Official Symbol    CTNNBIP1 [Similar Products]
 NCBI Official Synonym Symbols   
ICAT
[Similar Products]
 NCBI Protein Information    beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; inhibitor of beta-catenin and Tcf-4
 UniProt Protein Name    Beta-catenin-interacting protein 1
 UniProt Synonym Protein Names   
Inhibitor of beta-catenin and Tcf-4
 Protein Family    Beta-catenin-interacting protein
 UniProt Gene Name    CTNNBIP1 [Similar Products]
 UniProt Synonym Gene Names    ICAT [Similar Products]
 UniProt Entry Name    CNBP1_HUMAN
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 NCBI Summary for CTNNBIP1    The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CTNNBIP1    CTNNBIP1: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. Belongs to the CTNNBIP1 family.

Protein type: Cell development/differentiation; Inhibitor

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: nucleoplasm; cytoplasm; nucleus; beta-catenin destruction complex; cytosol

Molecular Function: protein binding; beta-catenin binding

Biological Process: anterior/posterior pattern formation; positive regulation of monocyte differentiation; positive regulation of osteoblast differentiation; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; ureteric bud branching; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; negative regulation of protein binding; regulation of vascular permeability during acute inflammatory response; negative regulation of DNA binding
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 Research Articles on CTNNBIP1    1. Our results indicate that HDAC1 plays an important role in chondrogenesis and may represent a therapeutic target for modulation of cartilage development.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CTNNBIP1 recombinant proteinPathways associated with CTNNBIP1 recombinant protein
 Reference Product  PubMed Publications
 CLSTN1 recombinant protein  >2 publications with CTNNBIP1 and CLSTN1
 UBIAD1 recombinant protein  >1 publications with CTNNBIP1 and UBIAD1
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway antibodies  RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway Diagram
 Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway antibodies  Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By WNT In Cancer Pathway antibodies  Signaling By WNT In Cancer Pathway Diagram
 Signaling By Wnt Pathway antibodies  Signaling By Wnt Pathway Diagram
 TCF Dependent Signaling In Response To WNT Pathway antibodies  TCF Dependent Signaling In Response To WNT Pathway Diagram
 Wnt Signaling Pathway NetPath antibodies  Wnt Signaling Pathway NetPath Diagram
 Wnt Signaling Pathway antibodies  Wnt Signaling Pathway Diagram
 Wnt Signaling Pathway antibodies  Wnt Signaling Pathway Diagram
Diseases associated with CTNNBIP1 recombinant proteinOrgans/Tissues associated with CTNNBIP1 recombinant protein
 Disease Name  Pubmed Publications
 Liver Neoplasms Antibodies  >3 publications with CTNNBIP1 and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with CTNNBIP1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with CTNNBIP1 and Carcinoma, Hepatocellular
 Congenital Abnormalities Antibodies  >1 publications with CTNNBIP1 and Congenital Abnormalities
 Embryo Loss Antibodies  >1 publications with CTNNBIP1 and Embryo Loss
 Hepatomegaly Antibodies  >1 publications with CTNNBIP1 and Hepatomegaly
 Disease Models, Animal Antibodies  >1 publications with CTNNBIP1 and Disease Models, Animal
 Fibrosis Antibodies  >1 publications with CTNNBIP1 and Fibrosis
 Abnormalities, Multiple Antibodies  >1 publications with CTNNBIP1 and Abnormalities, Multiple
 Necrosis Antibodies  >1 publications with CTNNBIP1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with CTNNBIP1 and Blood
 Kidney Antibodies  >6 publications with CTNNBIP1 and Kidney
 Liver Antibodies  >5 publications with CTNNBIP1 and Liver
 Embryonic Tissue Antibodies  >3 publications with CTNNBIP1 and Embryonic Tissue
 Eye Antibodies  >3 publications with CTNNBIP1 and Eye
 Connective Tissue Antibodies  >3 publications with CTNNBIP1 and Connective Tissue
 Bone Antibodies  >3 publications with CTNNBIP1 and Bone
 Vascular Antibodies  >2 publications with CTNNBIP1 and Vascular
 Brain Antibodies  >2 publications with CTNNBIP1 and Brain
 Uncharacterized Tissue Antibodies  >1 publications with CTNNBIP1 and Uncharacterized Tissue
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