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Ctsg recombinant protein :: Cathepsin G Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS718416
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $785 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $930 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,055 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,170 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,170 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,190 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,690 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,780 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,810 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,260 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cathepsin G (Ctsg), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Cathepsin G

 Product Synonym Names    Vimentin-specific protease; VSP
 Product Gene Name   

Ctsg recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    21-261aa; Full Length
 Sequence    IIGGREARPH SYPYMAFLLI QSPEGLSACG GFLVREDFVL TAAHCLGSSI NVTLGAHNIQ MRERTQQLIT VLRAIRHPDY NPQNIRNDIM LLQLRRRARR SGSVKPVALP QASKKLQPGD LCTVAGWGRV SQSRGTNVLQ EVQLRVQMDQ MCANRFQFYN SQTQICVGNP RERKSAFRGD SGGPLVCSNV AQGIVSYGSN NGNPPAVFTK IQSFMPWIKR TMRRFAPRYQ RPANSLSQAQ T
 3D Structure    ModBase 3D Structure for P28293
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Ctsg recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Ctsg recombinant protein

   This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movent and mitosis.
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 SDS-PAGE of Ctsg recombinant protein    Ctsg recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Ctsg. It may not necessarily be applicable to this product.
 NCBI GI #    6681083
 NCBI GeneID    13035
 NCBI Accession #    NP_031826.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_007800.2 [Other Products]
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 UniProt Primary Accession #    P28293 [Other Products]
 UniProt Related Accession #    P28293 [Other Products]
 Molecular Weight    42.88kD
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 NCBI Official Full Name    cathepsin G preproprotein
 NCBI Official Synonym Full Names    cathepsin G
 NCBI Official Symbol    Ctsg [Similar Products]
 NCBI Official Synonym Symbols   
VSP; CatG
[Similar Products]
 NCBI Protein Information    cathepsin G
 UniProt Protein Name    Cathepsin G
 UniProt Synonym Protein Names   
Vimentin-specific protease; VSP
 Protein Family    Cathepsin
 UniProt Gene Name    Ctsg [Similar Products]
 UniProt Synonym Gene Names    VSP [Similar Products]
 UniProt Entry Name    CATG_MOUSE
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 NCBI Summary for Ctsg    This gene encodes a member of the peptidase S1 (chymotrypsin) family of serine endopeptidases. The encoded preproprotein is proteolytically processed to generate a mature protein product. This product appears to play a role in host defense, including inflammation and antigen processing. Homozygous knockout mice for this gene exhibit enhanced susceptibility to bacterial and fungal infection. [provided by RefSeq, Aug 2015]
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 UniProt Comments for Ctsg    CTSG: Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. Belongs to the peptidase S1 family.

Protein type: Motility/polarity/chemotaxis; EC 3.4.21.20; Protease

Cellular Component: cytoplasm; extracellular matrix; extracellular space; intermediate filament; intracellular membrane-bound organelle; membrane; nucleus; plasma membrane; secretory granule

Molecular Function: heparin binding; hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: defense response to fungus; defense response to Gram-positive bacterium; immune response; positive regulation of immune response; protein amino acid phosphorylation; protein processing; proteolysis; response to lipopolysaccharide
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Product References and Citations for Ctsg recombinant protein

   Molecular cloning, chromosomal location, and tissue-specific expression of the murine cathepsin G gene.Heusel J.W., Scarpati E.M., Jenkins N.A., Gilbert D.J., Copeland N.G., Shapiro S.D., Ley T.J.Blood 81:1614-1623(1993) Kulmburg P., Baumruker T., Werner F.Huang R., Aveskogh M., Hellman L.T. Purification and characterization of a vimentin-specific protease in mouse myeloid leukemia cells. Regulation during differentiation and identity with cathepsin G.Nakamura N., Tsuru A., Hirayoshi K., Nagata K.Eur. J. Biochem. 205:947-954(1992)
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 Research Articles on Ctsg    1. Cathepsin G activity may impair efferocytosis, which could lead to an accumulation of lesion-associated apoptotic cells and the accelerated progression of early atherosclerotic lesions to more complex lesions in Apoe(-/-) mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Ctsg recombinant proteinDiseases associated with Ctsg recombinant protein
 Products by Pathway  Pathway Diagram
 Activation Of Matrix Metalloproteinases Pathway antibodies  Activation Of Matrix Metalloproteinases Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies  Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >148 publications with Ctsg and Inflammation
 Lung Diseases Antibodies  >61 publications with Ctsg and Lung Diseases
 Cardiovascular Diseases Antibodies  >45 publications with Ctsg and Cardiovascular Diseases
 Leukemia Antibodies  >37 publications with Ctsg and Leukemia
 Necrosis Antibodies  >33 publications with Ctsg and Necrosis
 Fibrosis Antibodies  >28 publications with Ctsg and Fibrosis
 Kidney Diseases Antibodies  >10 publications with Ctsg and Kidney Diseases
 Carcinoma Antibodies  >10 publications with Ctsg and Carcinoma
 Hemorrhage Antibodies  >10 publications with Ctsg and Hemorrhage
 Breast Neoplasms Antibodies  >6 publications with Ctsg and Breast Neoplasms
Organs/Tissues associated with Ctsg recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >622 publications with Ctsg and Blood
 Bone Antibodies  >42 publications with Ctsg and Bone
 Bone Marrow Antibodies  >31 publications with Ctsg and Bone Marrow
 Spleen Antibodies  >7 publications with Ctsg and Spleen
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