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Add To Compare List Ctsl1 recombinant protein :: Cathepsin L1 (Ctsl1) Recombinant Protein Catalog # MBS952452 Unit / Price 0.02 mg (E-Coli) / $850 +1 FREE 8GB USB 0.02 mg (Yeast) / $990 +1 FREE 8GB USB 0.1 mg (E-Coli) / $1,020 +1 FREE 8GB USB 0.1 mg (Yeast) / $1,125 +1 FREE 8GB USB 0.02 mg (Baculovirus) / $1,200 +1 FREE 8GB USB 0.02 mg (Mammalian-Cell) / $1,465 +1 FREE 8GB USB 0.1 mg (Baculovirus) / $1,720 +2 FREE 8GB USB 1 mg (E-Coli) / $1,815 +2 FREE 8GB USB 1 mg (Yeast) / $2,225 +2 FREE 8GB USB 0.1 mg (Mammalian-Cell) / $2,305 +2 FREE 8GB USB 1 mg (Baculovirus) / $3,360 +4 FREE 8GB USB 0.5 mg (Mammalian-Cell) / $5,995 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Cathepsin L1 (Ctsl1), Recombinant Protein Full Product Name Recombinant Rat Cathepsin L1 (Ctsl1) Product Gene Name Ctsl1 recombinant protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 114-288aa; Partial(Cathepsin L heavy chain) Sequence IPKTVDWREK GCVTPVKNQG QCGSCWAFSA SGCLEGQMFL KTGKLISLSE QNLVDCSHDQ GNQGCNGGLM DFAFQYIKEN GGLDSEESYP YEAKDGSCKY RAEYAVANDT GFVDIPQQEK ALMKAVATVG PISVAMDASH PSLQFYSSGI YYEPNCSSKD LDHGVLVVGY GYEGT 3D Structure ModBase 3D Structure for P07154 Host E Coli or Yeast or Baculovirus or Mammalian Cell Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized or liquid (Format to be determined during the manufacturing process) Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Species Rat Preparation and Storage Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of Ctsl1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for Ctsl1 recombinant protein This protein is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene. NCBI/Uniprot data below describe general gene information for Ctsl1. It may not necessarily be applicable to this product. NCBI GI # 6978723 NCBI GeneID 25697 NCBI Accession # NP_037288.1 [Other Products] NCBI GenBank Nucleotide # NM_013156.2 [Other Products] UniProt Primary Accession # P07154 [Other Products] UniProt Secondary Accession # Q9QV07[Other Products] UniProt Related Accession # P07154[Other Products] Molecular Weight 37,660 Da TOP NCBI Official Full Name cathepsin L1 preproprotein NCBI Official Synonym Full Names cathepsin L NCBI Official Symbol Ctsl [Similar Products] NCBI Official Synonym Symbols CatL; CATHL; Ctsl1 [Similar Products] NCBI Protein Information cathepsin L1 UniProt Protein Name Cathepsin L1 UniProt Synonym Protein Names Cathepsin L; Cyclic protein 2; CP-2 UniProt Gene Name Ctsl [Similar Products] UniProt Synonym Gene Names Ctsl1; CP-2; MEP [Similar Products] TOP NCBI Summary for Ctsl1 mouse homolog is deleted in the CD4 T-cell-deficient mouse mutant nacht (nkt); may play a role in CD4+ T-cell selection in the thymus [RGD, Feb 2006] TOP UniProt Comments for Ctsl1 Important for the overall degradation of proteins in lysosomes. Procathepsin L is required for maximal stimulation of steroidogenesis by TIMP1. Research Articles on Ctsl1 1. the activation of cathepsin L contributes to the irreversible depolarization produced by oxygen and glucose deprivation TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. 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TOP Products associated with Ctsl1 recombinant protein Reference Product PubMed Publications Ctsb recombinant protein >42 publications with Ctsl1 and Ctsb Ctsd recombinant protein >12 publications with Ctsl1 and Ctsd Mmp13 recombinant protein >3 publications with Ctsl1 and Mmp13 Col18a1 recombinant protein >2 publications with Ctsl1 and Col18a1 Ifi30 recombinant protein >1 publications with Ctsl1 and Ifi30 Cd74 recombinant protein >1 publications with Ctsl1 and Cd74 Pathways associated with Ctsl1 recombinant protein Products by Pathway Pathway Diagram Activation Of Matrix Metalloproteinases Pathway antibodies Activation Of Matrix Metalloproteinases Pathway Diagram Adaptive Immune System Pathway antibodies Adaptive Immune System Pathway Diagram Antigen Processing And Presentation Pathway antibodies Antigen Processing And Presentation Pathway Diagram Antigen Processing And Presentation Pathway antibodies Antigen Processing And Presentation Pathway Diagram Degradation Of The Extracellular Matrix Pathway antibodies Degradation Of The Extracellular Matrix Pathway Diagram Endochondral Ossification Pathway antibodies Endochondral Ossification Pathway Diagram Extracellular Matrix Organization Pathway antibodies Extracellular Matrix Organization Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Lysosome Pathway antibodies Lysosome Pathway Diagram Lysosome Pathway antibodies Lysosome Pathway Diagram Diseases associated with Ctsl1 recombinant protein Disease Name Pubmed Publications Disease Models, Animal Antibodies >53 publications with Ctsl1 and Disease Models, Animal Nervous System Diseases Antibodies >41 publications with Ctsl1 and Nervous System Diseases Neoplasm Metastasis Antibodies >29 publications with Ctsl1 and Neoplasm Metastasis Inflammation Antibodies >25 publications with Ctsl1 and Inflammation Cardiovascular Diseases Antibodies >25 publications with Ctsl1 and Cardiovascular Diseases Neoplasms, Experimental Antibodies >23 publications with Ctsl1 and Neoplasms, Experimental Liver Diseases Antibodies >23 publications with Ctsl1 and Liver Diseases Kidney Diseases Antibodies >22 publications with Ctsl1 and Kidney Diseases Necrosis Antibodies >18 publications with Ctsl1 and Necrosis Proteinuria Antibodies >15 publications with Ctsl1 and Proteinuria Organs/Tissues associated with Ctsl1 recombinant protein Organ/Tissue Name Pubmed Publications Liver Antibodies >127 publications with Ctsl1 and Liver Kidney Antibodies >75 publications with Ctsl1 and Kidney Muscle Antibodies >71 publications with Ctsl1 and Muscle Brain Antibodies >65 publications with Ctsl1 and Brain Spleen Antibodies >33 publications with Ctsl1 and Spleen Lung Antibodies >33 publications with Ctsl1 and Lung Testis Antibodies >25 publications with Ctsl1 and Testis Heart Antibodies >25 publications with Ctsl1 and Heart Thymus Antibodies >24 publications with Ctsl1 and Thymus Connective Tissue Antibodies >19 publications with Ctsl1 and Connective Tissue TOP © 2006-24 MyBioSource.com. 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