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ctss recombinant protein :: Cathepsin S Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1249669
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $765 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $910 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,025 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,150 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,150 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,160 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,660 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,755 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,765 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,215 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cathepsin S (ctss), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Cathepsin S

 Product Gene Name   

ctss recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1249669 COA    COA PDF
 Sequence Positions    123-340. Mature full length protein.
 Sequence    LPDTVDWREK GCVTEVKYQG SCGACWAFSA VGALEGQLKL KTGKLISLSA QNLVDCSNEE KYGNKGCGGG YMTEAFQYII DNGGIEADAS YPYKATDEKC HYNSKNRAAT CSRYIQLPFG DEDALKEAVA TKGPVSVGID ASHSSFFFYK SGVYDDPSCT GNVNHGVLVV GYGTLDGKDY WLVKNSWGLN FGDQGYIRMA RNNKNHCGIA SYCSYPEI
 3D Structure    ModBase 3D Structure for O70370
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ctss recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ctss recombinant protein

   Thiol protease. Key protease responsible for the roval of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
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 SDS-PAGE of ctss recombinant protein    ctss recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for ctss. It may not necessarily be applicable to this product.
 NCBI GI #    510025483
 NCBI GeneID    13040
 NCBI Accession #    NP_067256.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_021281.3 [Other Products]
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 UniProt Primary Accession #    O70370 [Other Products]
 UniProt Secondary Accession #    O54973; E9QK18 [Other Products]
 UniProt Related Accession #    O70370 [Other Products]
 Molecular Weight    27.8kD
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 NCBI Official Full Name    cathepsin S isoform 2 preproprotein
 NCBI Official Synonym Full Names    cathepsin S
 NCBI Official Symbol    Ctss [Similar Products]
 NCBI Official Synonym Symbols   
Cats
[Similar Products]
 NCBI Protein Information    cathepsin S
 UniProt Protein Name    Cathepsin S
 Protein Family    Cathepsin
 UniProt Gene Name    Ctss [Similar Products]
 UniProt Synonym Gene Names    Cats [Similar Products]
 UniProt Entry Name    CATS_MOUSE
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 NCBI Summary for ctss    This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. Alternative splicing results in multiple transcript variants, which encode preproproteins that are proteolytically processed to generate mature protein products. This enzyme is secreted by antigen-presenting cells during inflammation and may induce pain and itch via activation of G-protein coupled receptors. Homozygous knockout mice for this gene exhibit impaired wound healing, reduced tumorigenesis in a pancreatic cancer model, and reduced pathogenesis in a myasthenia gravis model. [provided by RefSeq, Aug 2015]
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 UniProt Comments for ctss    CTSS: Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. Belongs to the peptidase C1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; EC 3.4.22.27

Cellular Component: cell surface; extracellular space; intracellular membrane-bound organelle; lysosome; membrane

Molecular Function: collagen binding; cysteine-type endopeptidase activity; cysteine-type peptidase activity; fibronectin binding; hydrolase activity; laminin binding; peptidase activity; proteoglycan binding

Biological Process: antigen processing and presentation; antigen processing and presentation of peptide antigen; bone resorption; collagen catabolic process; immune response; positive regulation of inflammatory response; protein processing; proteolysis; proteolysis involved in cellular protein catabolic process; regulation of sensory perception of pain; response to acidity
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Product References and Citations for ctss recombinant protein

   Doh-ura K. Rommerskirch W. Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009) Cathepsin expression during skeletal development.Soederstroem M., Salminen H., Glumoff V., Kirschke H., Aro H., Vuorio E.Biochim. Biophys. Acta 1446:35-46(1999) Gene expression in scrapie. Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts.Dandoy-Dron F., Guillo F., Benboudjema L., Deslys J.-P., Lasmesas C., Dormont D., Tovey M.G., Dron M.J. Biol. Chem. 273:7691-7697(1998)
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 Research Articles on ctss    1. cathepsin S deficiency alters the balance between adipocyte and osteoblast differentiation, increases bone turnover, and changes bone microarchitecture. Therefore, bone and fat metabolisms should be monitored when using cathepsin S inhibitors clinically
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ctss recombinant proteinPathways associated with ctss recombinant protein
 Reference Product  PubMed Publications
 Ctsd recombinant protein  >4 publications with ctss and Ctsd
 Tlr7 recombinant protein  >2 publications with ctss and Tlr7
 B2m recombinant protein  >1 publications with ctss and B2m
 Lgmn recombinant protein  >1 publications with ctss and Lgmn
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
Diseases associated with ctss recombinant proteinOrgans/Tissues associated with ctss recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >18 publications with ctss and Nervous System Diseases
 Inflammation Antibodies  >18 publications with ctss and Inflammation
 Cardiovascular Diseases Antibodies  >13 publications with ctss and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >10 publications with ctss and Disease Models, Animal
 Obesity Antibodies  >9 publications with ctss and Obesity
 Atherosclerosis Antibodies  >6 publications with ctss and Atherosclerosis
 Fibrosis Antibodies  >5 publications with ctss and Fibrosis
 Heart Diseases Antibodies  >5 publications with ctss and Heart Diseases
 Kidney Diseases Antibodies  >4 publications with ctss and Kidney Diseases
 Hypertension Antibodies  >3 publications with ctss and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >23 publications with ctss and Blood
 Brain Antibodies  >13 publications with ctss and Brain
 Muscle Antibodies  >11 publications with ctss and Muscle
 Liver Antibodies  >7 publications with ctss and Liver
 Embryonic Tissue Antibodies  >6 publications with ctss and Embryonic Tissue
 Lung Antibodies  >6 publications with ctss and Lung
 Bone Antibodies  >4 publications with ctss and Bone
 Spleen Antibodies  >3 publications with ctss and Spleen
 Joint Antibodies  >3 publications with ctss and Joint
 Spinal Cord Antibodies  >3 publications with ctss and Spinal Cord
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