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Add To Compare List CAV1 recombinant protein :: Caveolin-1 (CAV1) Recombinant Protein Catalog # MBS1390995 Unit / Price 0.02 mg (E-Coli) / $685 +1 FREE 8GB USB 0.1 mg (E-Coli) / $815 +1 FREE 8GB USB 0.02 mg (Yeast) / $860 +1 FREE 8GB USB 0.1 mg (Yeast) / $1,000 +1 FREE 8GB USB 0.02 mg (Baculovirus) / $1,105 +1 FREE 8GB USB 0.02 mg (Mammalian-Cell) / $1,335 +1 FREE 8GB USB 1 mg (E-Coli) / $1,435 +1 FREE 8GB USB 0.1 mg (Baculovirus) / $1,530 +1 FREE 8GB USB 1 mg (Yeast) / $1,960 +2 FREE 8GB USB 0.1 mg (Mammalian-Cell) / $2,160 +2 FREE 8GB USB 1 mg (Baculovirus) / $3,015 +3 FREE 8GB USB 0.5 mg (Mammalian-Cell) / $5,800 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Caveolin-1 (CAV1), Recombinant Protein Full Product Name Recombinant Pig Caveolin-1 (CAV1) Product Gene Name CAV1 recombinant protein[Similar Products] Product Synonym Gene Name CAV1[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 2-178, Full length protein Sequence SGGKYVDSEG HLYTVPIREQ GNIYKPNNKA MAEEMNEKQV YDAHTKEIDL VNRDPKHLND DVVKIDFEDV IAEPEGTHSF DGIWKASFTT FTVTKYWFYR LLSALFGIPM ALIWGIYFAI LSFLHIWAVV PCIKSFLIEI QCISRVYSIY VHTFCDPLFE AIGKIFSNIR INMQKEI 3D Structure ModBase 3D Structure for Q6RVA9 Host E Coli or Yeast or Baculovirus or Mammalian Cell Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized or liquid (Format to be determined during the manufacturing process) Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Species Sus scrofa (Pig) Preparation and Storage Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of CAV1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for CAV1 recombinant protein The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p4244 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. NCBI/Uniprot data below describe general gene information for CAV1. It may not necessarily be applicable to this product. NCBI GI # 47523930 NCBI GeneID 404693 NCBI Accession # NP_999603.1 [Other Products] NCBI GenBank Nucleotide # NM_214438.2 [Other Products] UniProt Primary Accession # Q6RVA9 [Other Products] UniProt Secondary Accession # Q0PHA2; Q2QLE1[Other Products] UniProt Related Accession # Q6RVA9[Other Products] Molecular Weight 20,625 Da TOP NCBI Official Full Name caveolin-1 NCBI Official Symbol CAV1 [Similar Products] NCBI Protein Information caveolin-1 UniProt Protein Name Caveolin-1 Protein Family Caveolin UniProt Gene Name CAV1 [Similar Products] TOP TOP UniProt Comments for CAV1 Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Research Articles on CAV1 1. Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with CAV1 recombinant protein Reference Product PubMed Publications CAV2 recombinant protein >195 publications with CAV1 and CAV2 SRC recombinant protein >153 publications with CAV1 and SRC NOS3 recombinant protein >111 publications with CAV1 and NOS3 EGFR recombinant protein >51 publications with CAV1 and EGFR FYN recombinant protein >25 publications with CAV1 and FYN TRPC1 recombinant protein >16 publications with CAV1 and TRPC1 HSP90AA1 recombinant protein >1 publications with CAV1 and HSP90AA1 Pathways associated with CAV1 recombinant protein Products by Pathway Pathway Diagram Bacterial Invasion Of Epithelial Cells Pathway antibodies Bacterial Invasion Of Epithelial Cells Pathway Diagram Bacterial Invasion Of Epithelial Cells Pathway antibodies Bacterial Invasion Of Epithelial Cells Pathway Diagram Basigin Interactions Pathway antibodies Basigin Interactions Pathway Diagram Cell Surface Interactions At The Vascular Wall Pathway antibodies Cell Surface Interactions At The Vascular Wall Pathway Diagram Disassembly Of The Destruction Complex And Recruitment Of AXIN To The Membrane Pathway antibodies Disassembly Of The Destruction Complex And Recruitment Of AXIN To The Membrane Pathway Diagram Endocytosis Pathway antibodies Endocytosis Pathway Diagram Endocytosis Pathway antibodies Endocytosis Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram Hemostasis Pathway antibodies Hemostasis Pathway Diagram Diseases associated with CAV1 recombinant protein Disease Name Pubmed Publications Cardiovascular Diseases Antibodies >238 publications with CAV1 and Cardiovascular Diseases Heart Diseases Antibodies >148 publications with CAV1 and Heart Diseases Hypertension Antibodies >124 publications with CAV1 and Hypertension Lung Diseases Antibodies >122 publications with CAV1 and Lung Diseases Breast Neoplasms Antibodies >105 publications with CAV1 and Breast Neoplasms Adenocarcinoma Antibodies >94 publications with CAV1 and Adenocarcinoma Inflammation Antibodies >91 publications with CAV1 and Inflammation Neoplasm Metastasis Antibodies >78 publications with CAV1 and Neoplasm Metastasis Fibrosis Antibodies >72 publications with CAV1 and Fibrosis Prostatic Neoplasms Antibodies >64 publications with CAV1 and Prostatic Neoplasms Organs/Tissues associated with CAV1 recombinant protein Organ/Tissue Name Pubmed Publications Muscle Antibodies >634 publications with CAV1 and Muscle Heart Antibodies >381 publications with CAV1 and Heart Lung Antibodies >220 publications with CAV1 and Lung Kidney Antibodies >164 publications with CAV1 and Kidney Liver Antibodies >115 publications with CAV1 and Liver Prostate Antibodies >89 publications with CAV1 and Prostate Eye Antibodies >81 publications with CAV1 and Eye Aorta Antibodies >76 publications with CAV1 and Aorta Embryonic Tissue Antibodies >76 publications with CAV1 and Embryonic Tissue Intestine Antibodies >64 publications with CAV1 and Intestine TOP © 2006-24 MyBioSource.com. 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