NP_001263395.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
20,800 Da
NCBI Official Full Name
cbp/p300-interacting transactivator 1 isoform a
NCBI Official Synonym Full Names
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
NCBI Protein Information
cbp/p300-interacting transactivator 1
UniProt Protein Name
Cbp/p300-interacting transactivator 1
UniProt Synonym Protein Names
Melanocyte-specific protein 1
UniProt Synonym Gene Names
UniProt Comments for Cited1
Transcriptional coactivator of the p300/CBP-mediated transcription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
Research Articles on Cited1
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Pathways associated with Cited1 recombinant protein
Diseases associated with Cited1 recombinant protein
Organs/Tissues associated with Cited1 recombinant protein
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