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Cdc6 recombinant protein :: Cell division control protein 6 homolog (Cdc6) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1250869 Cdc6 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,360 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,360 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,575 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,575 +1 FREE 8GB USB
1 mg (E-Coli)  /  $2,255 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $2,255 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,720 +3 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,720 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cell division control protein 6 homolog (Cdc6), Recombinant Protein

 Also Known As   

Recombinant Mouse Cell division control protein 6 homolog (Cdc6)

 Product Synonym Names    Cell division control protein 6 homolog; CDC6-related protein; p62(cdc6)
 Product Gene Name   

Cdc6 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-562
 Sequence    MPQTRSQTQA TIGFPKKKLS NTLKKPNSRD CEVKLRNVQP VPTTPCVDVK LLPLSPRKRL GDDNLCNTPR LSPCSPPKLG KKENGPPRSH TWKGCRLVFD DEPTFKASPP KEQDRVRQHQ IRSSSAQRSP ESKADPEQKC PPEKESVCIR LFKQEGTCYQ QAKLVLNTAV PDRLPAREQE MGVIRNFLKE HICGKKAGSL YLSGAPGTGK TACLSRILQD FKKEVKGFKS ILLNCMSLRS AQAVFPAIAQ EIGREELCRP AGKDLMRKLE KHLTAEKGPM IVLVLDEMDQ LDSKGQDVLY TLFEWPWLSN SRLVLIGIAN TLDLTDRILP RLEARENCKP QLLNFPPYTR NQIAAILQDR LSQVSKDQVL DSAAIQFCAR KVSAVSGDIR KALDVCRRAI EIVESDVRSQ TVLKPLSECK SPSESPVPKR VGLAHISQVI SEVDGNRVTL SQENTQDSLP LQQKILVCSL LLLTRRLKIK EVTLGKLYEA YSSICRKQQV TAVDQSECLS LSGLLESRGL VGLKKNKESR LTKVSLKIEE KEIEHVLNGK AFTGNILAAG LP
 3D Structure    ModBase 3D Structure for O89033
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Cdc6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Cdc6. It may not necessarily be applicable to this product.
 NCBI GI #    71061453
 NCBI GeneID    23834
 NCBI Accession #    NP_001020950.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001025779.1 [Other Products]
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 UniProt Primary Accession #    O89033 [Other Products]
 UniProt Secondary Accession #    Q3TMD0; Q8C3S5; Q9CZT0 [Other Products]
 UniProt Related Accession #    O89033 [Other Products]
 Molecular Weight    62,614 Da
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 NCBI Official Full Name    cell division control protein 6 homolog isoform b
 NCBI Official Synonym Full Names    cell division cycle 6
 NCBI Official Symbol    Cdc6 [Similar Products]
 NCBI Official Synonym Symbols   
CDC18L
[Similar Products]
 NCBI Protein Information    cell division control protein 6 homolog; p62(cdc6); CDC18(S.pombe); CDC6-related protein; cell division cycle 6 homolog
 UniProt Protein Name    Cell division control protein 6 homolog
 UniProt Synonym Protein Names   
CDC6-related protein; p62(cdc6)
 Protein Family    Cell division control protein
 UniProt Gene Name    Cdc6 [Similar Products]
 UniProt Entry Name    CDC6_MOUSE
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 UniProt Comments for Cdc6    CDC6: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. Interacts with PCNA, ORC1L, cyclin-CDK and HUWE1. Belongs to the CDC6/cdc18 family.

Protein type: Cell cycle regulation

Cellular Component: nucleoplasm; spindle pole; Golgi apparatus; cytoplasm; spindle; spindle midzone; nucleus

Molecular Function: nucleotide binding; chromatin binding; kinase binding; ATP binding

Biological Process: positive regulation of cytokinesis; mitosis; cell division; regulation of mitotic metaphase/anaphase transition; positive regulation of chromosome segregation; cell cycle; DNA replication
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 Research Articles on Cdc6    1. Cdc6 continued to block apoptosome assembly induced by a non-cytochrome c or some other mechanism, suppressing seemingly unintended apoptosis when promoting cell proliferation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Cdc6 recombinant proteinDiseases associated with Cdc6 recombinant protein
 Products by Pathway  Pathway Diagram
 Activation Of ATR In Response To Replication Stress Pathway antibodies  Activation Of ATR In Response To Replication Stress Pathway Diagram
 Activation Of The Pre-replicative Complex Pathway antibodies  Activation Of The Pre-replicative Complex Pathway Diagram
 Assembly Of The Pre-replicative Complex Pathway antibodies  Assembly Of The Pre-replicative Complex Pathway Diagram
 Association Of Licensing Factors With The Pre-replicative Complex Pathway antibodies  Association Of Licensing Factors With The Pre-replicative Complex Pathway Diagram
 CDC6 Association With The ORC:origin Complex Pathway antibodies  CDC6 Association With The ORC:origin Complex Pathway Diagram
 CDK-mediated Phosphorylation And Removal Of Cdc6 Pathway antibodies  CDK-mediated Phosphorylation And Removal Of Cdc6 Pathway Diagram
 CDT1 Association With The CDC6:ORC:origin Complex Pathway antibodies  CDT1 Association With The CDC6:ORC:origin Complex Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Disease Name  Pubmed Publications
 Ataxia Antibodies  >19 publications with Cdc6 and Ataxia
 Adenocarcinoma Antibodies  >13 publications with Cdc6 and Adenocarcinoma
 Prostatic Neoplasms Antibodies  >13 publications with Cdc6 and Prostatic Neoplasms
 Breast Neoplasms Antibodies  >12 publications with Cdc6 and Breast Neoplasms
 Lung Neoplasms Antibodies  >9 publications with Cdc6 and Lung Neoplasms
 Carcinoma, Hepatocellular Antibodies  >8 publications with Cdc6 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >7 publications with Cdc6 and Liver Diseases
 Neoplasm Metastasis Antibodies  >6 publications with Cdc6 and Neoplasm Metastasis
 Meier-Gorlin syndrome Antibodies  >6 publications with Cdc6 and Meier-Gorlin syndrome
 Liver Neoplasms Antibodies  >5 publications with Cdc6 and Liver Neoplasms
Organs/Tissues associated with Cdc6 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >19 publications with Cdc6 and Lung
 Bone Antibodies  >15 publications with Cdc6 and Bone
 Liver Antibodies  >9 publications with Cdc6 and Liver
 Lymph Node Antibodies  >8 publications with Cdc6 and Lymph Node
 Bone Marrow Antibodies  >4 publications with Cdc6 and Bone Marrow
 Ovary Antibodies  >4 publications with Cdc6 and Ovary
 Skin Antibodies  >4 publications with Cdc6 and Skin
 Eye Antibodies  >3 publications with Cdc6 and Eye
 Kidney Antibodies  >2 publications with Cdc6 and Kidney
 Heart Antibodies  >2 publications with Cdc6 and Heart
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