NP_990595.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
40,169 Da
NCBI Official Full Name
cellular tumor antigen p53
NCBI Official Synonym Full Names
tumor protein p53
NCBI Protein Information
cellular tumor antigen p53
UniProt Protein Name
Cellular tumor antigen p53
UniProt Synonym Protein Names
Tumor suppressor p53
UniProt Comments for TP53
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression ().
Research Articles on TP53
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Pathways associated with TP53 recombinant protein
Diseases associated with TP53 recombinant protein
Organs/Tissues associated with TP53 recombinant protein
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