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Ugcg recombinant protein :: Ceramide glucosyltransferase (Ugcg) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1214011
SDS-PAGE
Unit / Price
0.5 mg (E-Coli)  /  $940 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $940 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,165 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,165 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,350 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,350 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,810 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,810 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,845 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,630 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ceramide glucosyltransferase (Ugcg), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Ceramide glucosyltransferase (Ugcg)

 Product Synonym Names    Recombinant Ceramide glucosyltransferase (Ugcg); Ceramide glucosyltransferase EC= 2.4.1.80; GLCT-1 Glucosylceramide synthase; GCS UDP-glucose ceramide glucosyltransferase UDP-glucose:N-acylsphingosine D-glucosyltransferase
 Product Gene Name   

Ugcg recombinant protein

[Similar Products]
 Product Synonym Gene Name    Ugcg [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    33-195. Partial, provide one of the complete extracellular domain.
 Sequence    TRLHLNKKAT DKQPYSKLPG VSLLKPLKGV DPNLINNLET FFELDYPKYE VLLCVQDHDD PAIDVCKKLL GKYPNVDARL FIGGKKVGIN PKINNLMPAY EVAKYDLIWI CDSGIRVIPD TLTDMVNQMT EKVGLVHGLP YVADRQGFAA TLEQVYFGTS HPR
 Chromosome Location    Chromosome: 4; NC_000070.6 (59189550..59222833). Location: 4 B3; 4 32.44 cM
 3D Structure    ModBase 3D Structure for O88693
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90%(SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Ugcg recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Ugcg recombinant protein

   Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase" (By similarity).
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 SDS-PAGE of Ugcg recombinant protein    Ugcg recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Ugcg. It may not necessarily be applicable to this product.
 NCBI GI #    7106443
 NCBI GeneID    22234
 NCBI Accession #    NP_035803.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_011673.3 [Other Products]
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 UniProt Primary Accession #    O88693 [Other Products]
 UniProt Secondary Accession #    A2AN90 [Other Products]
 UniProt Related Accession #    O88693 [Other Products]
 Molecular Weight    59kD [Similar Products]
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 NCBI Official Full Name    ceramide glucosyltransferase
 NCBI Official Synonym Full Names    UDP-glucose ceramide glucosyltransferase
 NCBI Official Symbol    Ugcg [Similar Products]
 NCBI Official Synonym Symbols   
Ugcgl; C80537; Epcs21; GlcT-1; AU043821
[Similar Products]
 NCBI Protein Information    ceramide glucosyltransferase; GCS; glucosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase; ectoplacental cone, invasive trophoblast giant cells, extraembryonic ectoderm and chorion sequence 21
 UniProt Protein Name    Ceramide glucosyltransferase
 UniProt Synonym Protein Names   
GLCT-1; Glucosylceramide synthase; GCS; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase
 Protein Family    Ceramide glucosyltransferase
 UniProt Gene Name    Ugcg [Similar Products]
 UniProt Synonym Gene Names    GCS [Similar Products]
 UniProt Entry Name    CEGT_MOUSE
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 UniProt Comments for Ugcg    UGCG: Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a flippase. Belongs to the glycosyltransferase 2 family.

Protein type: Lipid Metabolism - sphingolipid; Membrane protein, integral; Transferase; EC 2.4.1.80; Membrane protein, multi-pass

Cellular Component: Golgi apparatus; membrane; integral to membrane

Molecular Function: transferase activity; ceramide glucosyltransferase activity; transferase activity, transferring glycosyl groups

Biological Process: sphingolipid metabolic process; glucosylceramide biosynthetic process; lipid metabolic process
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 Research Articles on Ugcg    1. glycosphingolipids in hepatocytes are not essential for sterol, glucose, or lipoprotein metabolism. Ugcg inhibitors exert their effect on hepatocytes either independently of GSL or mediated by other (liver) cell types.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Ugcg recombinant proteinDiseases associated with Ugcg recombinant protein
 Products by Pathway  Pathway Diagram
 Lactosylceramide Biosynthesis Pathway antibodies  Lactosylceramide Biosynthesis Pathway Diagram
 Lactosylceramide Biosynthesis Pathway antibodies  Lactosylceramide Biosynthesis Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipids Metabolism Pathway antibodies  Sphingolipids Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with Ugcg and Neoplasms
 Nervous System Diseases Antibodies  >4 publications with Ugcg and Nervous System Diseases
 Fatty Liver Antibodies  >3 publications with Ugcg and Fatty Liver
 Brain Diseases Antibodies  >3 publications with Ugcg and Brain Diseases
 Kidney Diseases Antibodies  >3 publications with Ugcg and Kidney Diseases
 Inflammation Antibodies  >2 publications with Ugcg and Inflammation
 Neural Tube Defects Antibodies  >1 publications with Ugcg and Neural Tube Defects
 Drug Toxicity Antibodies  >1 publications with Ugcg and Drug Toxicity
 Liver Diseases Antibodies  >1 publications with Ugcg and Liver Diseases
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with Ugcg and Prenatal Exposure Delayed Effects
Organs/Tissues associated with Ugcg recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >11 publications with Ugcg and Other
 Brain Antibodies  >6 publications with Ugcg and Brain
 Liver Antibodies  >4 publications with Ugcg and Liver
 Kidney Antibodies  >3 publications with Ugcg and Kidney
 Stomach Antibodies  >1 publications with Ugcg and Stomach
 Blood Antibodies  >1 publications with Ugcg and Blood
 Spinal Cord Antibodies  >1 publications with Ugcg and Spinal Cord
 Heart Antibodies  >1 publications with Ugcg and Heart
 Skin Antibodies  >1 publications with Ugcg and Skin
 Ovary Antibodies  >1 publications with Ugcg and Ovary
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