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CHMP2B recombinant protein :: Charged multivesicular body protein 2b (CHMP2B) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1316787 CHMP2B recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $960 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $960 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,185 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,185 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,445 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,445 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,910 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,910 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Charged multivesicular body protein 2b (CHMP2B), Recombinant Protein

 Also Known As   

Recombinant Bovine Charged multivesicular body protein 2b (CHMP2B)

 Product Synonym Names    Charged multivesicular body protein 2b; Chromatin-modifying protein 2b; CHMP2b
 Product Gene Name   

CHMP2B recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-213
 Sequence    ASLFKKKTV DDVIKEQNRE LRGTQRAIIR DRAALEKQEK QLELEIKKMA KIGNKEACRV LAKQLVHLRK QKTRTFAVSS KVTSMSTQTK VMNSQMKMAG AMSTTAKTMQ AVNKKMDPQK TLQTMQNFQK ENMKMEMTEE MINDTLDDIF DGSDDEEESQ DIVNQVLDEI GIEISGKMAK APSAARSLPS ASTSKSTISD EEIERQLKAL GVD
 3D Structure    ModBase 3D Structure for Q3SX42
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Bos taurus (Bovine)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CHMP2B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CHMP2B. It may not necessarily be applicable to this product.
 NCBI GI #    78369212
 NCBI GeneID    615954
 NCBI Accession #    NP_001030549.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001035472.1 [Other Products]
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 UniProt Primary Accession #    Q3SX42 [Other Products]
 UniProt Related Accession #    Q3SX42 [Other Products]
 Molecular Weight    23,951 Da
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 NCBI Official Full Name    charged multivesicular body protein 2b
 NCBI Official Synonym Full Names    charged multivesicular body protein 2B<
 NCBI Official Symbol    CHMP2B [Similar Products]
 NCBI Protein Information    charged multivesicular body protein 2b; chromatin modifying protein 2B; chromatin-modifying protein 2b
 UniProt Protein Name    Charged multivesicular body protein 2b
 UniProt Synonym Protein Names   
Chromatin-modifying protein 2b; CHMP2b
 Protein Family    Charged multivesicular body protein
 UniProt Gene Name    CHMP2B [Similar Products]
 UniProt Synonym Gene Names    CHMP2b [Similar Products]
 UniProt Entry Name    CHM2B_BOVIN
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 UniProt Comments for CHMP2B    Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4 ().
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CHMP2B recombinant proteinPathways associated with CHMP2B recombinant protein
 Reference Product  PubMed Publications
 CHMP4B recombinant protein  >5 publications with CHMP2B and CHMP4B
 CHMP2A recombinant protein  >4 publications with CHMP2B and CHMP2A
 CHMP4A recombinant protein  >2 publications with CHMP2B and CHMP4A
 Products by Pathway  Pathway Diagram
 ESCRT-III Complex Pathway antibodies  ESCRT-III Complex Pathway Diagram
 ESCRT-III Complex Pathway antibodies  ESCRT-III Complex Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endosomal Sorting Complex Required For Transport (ESCRT) Pathway antibodies  Endosomal Sorting Complex Required For Transport (ESCRT) Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
Diseases associated with CHMP2B recombinant proteinOrgans/Tissues associated with CHMP2B recombinant protein
 Disease Name  Pubmed Publications
 Frontotemporal Dementia Antibodies  >75 publications with CHMP2B and Frontotemporal Dementia
 Frontotemporal Lobar Degeneration Antibodies  >48 publications with CHMP2B and Frontotemporal Lobar Degeneration
 Amyotrophic Lateral Sclerosis Antibodies  >28 publications with CHMP2B and Amyotrophic Lateral Sclerosis
 Atrophy Antibodies  >15 publications with CHMP2B and Atrophy
 Congenital Abnormalities Antibodies  >3 publications with CHMP2B and Congenital Abnormalities
 Frontotemporal Dementia, Chromosome 3-Linked Antibodies  >3 publications with CHMP2B and Frontotemporal Dementia, Chromosome 3-Linked
 Neurobehavioral Manifestations Antibodies  >1 publications with CHMP2B and Neurobehavioral Manifestations
 Learning Disorders Antibodies  >1 publications with CHMP2B and Learning Disorders
 Inflammation Antibodies  >1 publications with CHMP2B and Inflammation
 Hypertrophy Antibodies  >1 publications with CHMP2B and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >31 publications with CHMP2B and Brain
 Liver Antibodies  >1 publications with CHMP2B and Liver
 Uncharacterized Tissue Antibodies  >1 publications with CHMP2B and Uncharacterized Tissue
 Ovary Antibodies  >1 publications with CHMP2B and Ovary
 Embryonic Tissue Antibodies  >1 publications with CHMP2B and Embryonic Tissue
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