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CHIKV recombinant protein :: Chikungunya Mutant E1 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS144891 CHIKV recombinant protein
Unit / Price
0.002 mg  /  $140 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $5,015 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Chikungunya Mutant E1 (CHIKV), Recombinant Protein

 Also Known As   

Recombinant Chikungunya Mutant (A226V) E1

 Product Synonym Names    CHIKV Mutant; Chikungunya Mutant (A226V) E1 Recombinant; CHIKV Mutant
 Product Gene Name   

CHIKV recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    YEHVTVIPNT VGVPYKTLVN RPGYSPMVLE MELLSVTLEP TLSLDYITCE YKTVIPSPYV KCCGTAECKD KNLPDYSCKV FTGVYPFMWG GAYCFCDAEN TQLSEAHVEK SESCKTEFAS AYRAHTASAS AKLRVLYQGN NITVTAYANG DHAVTVKDAK FIVGPMSSAW TPFDNKIVVY KGDVYNMDYP PFGAGRPGQF GDIQSRTPES KDVYANTQLV LQRPAVGTVH VPYSQAPSGF KYWLKERGAS LQHTAPFGCQ IATNPVRAVN CAVGNMPISI DIPEAAFTRV VDAPSLTDMS CEVPACTHSS DFGGVAIIKY AASKKGKCAV HSMTNAVTIR EAEIEVEGNS QLQISFSTAL ASAEFRVQVC STQVHCAAEC HPPKDHIVNY PASHTTLGQD ISATAMSWVQ KITGG.
 3D Structure    ModBase 3D Structure for G0LWX6
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 Host    Insect Cells
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 Purity/Purification    Protein is >=95% pure as determined by 12.5% SDS-PAGE
 Form/Format    CHIKV Mutant protein solution in 1xD-PBS, pH7.4, 0.1% Thimerosal, 5mM EDTA, 1 ug/ml of Leupeptin, Aprotinin and Pepstatin A.
Sterile filtered colorless solution.
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 Preparation and Storage    Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
 Other Notes    Small volumes of CHIKV recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for CHIKV recombinant protein

   Description: Recombinant Chikungunya Mutant (A226V) E1 produced in Insect Cells is a polypeptide chain containing amino acids 1-415, however at position 226 the Alanine of the wild-type CHIKV E1 gene was mutated to Valine. The molecular weight of the CHIKV Mutant is approximately 50kDa. The E1 protein is C-terminal part of E2-6K-E1 protein region. CHIKV Mutant is purified by proprietary chromatographic technique.

Introduction: Chikungunya virus (CHIKV) is an arthropod-born virus which is a member of the Alphavirus genus belonging to the Togaviridae family. CHIKV nucleocapsid is comprised of a single-stranded plussense RNA genome of approximately 11.8 kb. The CHIKV virion envelope consists of a lipid bilayer derived from the plasma membrane from the host cell, multiple copies of 2 major virus encoded glycoproteins E1 and E2, and a small 6K peptide. Proteins E1 and E2 both have a molecular weight of roughly 50kDa and form a heterodimer anchored in the membrane. Chikungunya virus infection causes an illness with symptoms similar to those of the dengue fever with an acute febrile phase lasting only 2-5 days, followed by a prolonged arthralgic disease affecting the joint extremities. Recent Chikungunya virus outbreaks presented a prospect for genetic analysis of patients with the illness, revealing a point mutation at the amino acid 226 (Ala mutated to Val) of the E1 gene. This point mutation was confirmed to be responsible for an improved capacity of CHIKV strains to infect and replicate in the Aedes albopictus, enabling virus transmission to a naive human population.
 Product Categories/Family for CHIKV recombinant protein    VIRAL ANTIGENS- CHIKUNGUNYA VIRUS; Viral Antigens; Chikungunya
NCBI/Uniprot data below describe general gene information for CHIKV. It may not necessarily be applicable to this product.
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 UniProt Primary Accession #    G0LWX6 [Other Products]
 Molecular Weight    101,424 Da
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 UniProt Protein Name    Structural polyprotein, E2-6K-E1 region
 UniProt Synonym Protein Names   
Structural polyprotein, E2-6K-E1 region
 UniProt Gene Name    E2-6K-E1 [Similar Products]
 UniProt Entry Name    G0LWX6_CHIKV
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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