NP_033957.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,437 Da
NCBI Official Full Name
cholecystokinin receptor type A
NCBI Official Synonym Full Names
cholecystokinin A receptor
NCBI Official Synonym Symbols
NCBI Protein Information
cholecystokinin receptor type A
UniProt Protein Name
Cholecystokinin receptor type A
UniProt Synonym Protein Names
Cholecystokinin-1 receptor; CCK1-R
UniProt Synonym Gene Names
UniProt Entry Name
CCKAR_MOUSE
UniProt Comments for Cckar
CCKAR: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; endosome; integral to membrane; lysosome; membrane; plasma membrane; terminal button
Molecular Function: cholecystokinin receptor activity; G-protein coupled receptor activity; signal transducer activity
Biological Process: actin cytoskeleton reorganization; axonogenesis; digestion; eating behavior; elevation of cytosolic calcium ion concentration; feeding behavior; forebrain development; G-protein coupled receptor protein signaling pathway; gastric acid secretion; insulin secretion; neuron migration; pancreatic juice secretion; reduction of food intake in response to dietary excess; regulation of calcium ion transport; regulation of hormone secretion; regulation of potassium ion transport; response to heat; response to starvation; signal transduction; thermoregulation
Research Articles on Cckar
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Pathways associated with Cckar recombinant protein
Diseases associated with Cckar recombinant protein
Organs/Tissues associated with Cckar recombinant protein
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