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Cspg4 recombinant protein :: Chondroitin sulfate proteoglycan 4 (Cspg4) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS952539 Cspg4 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,435 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,435 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,660 +2 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,660 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,390 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $2,390 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,805 +3 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,805 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Chondroitin sulfate proteoglycan 4 (Cspg4), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rat Chondroitin sulfate proteoglycan 4 (Cspg4) , partial

 Product Gene Name   

Cspg4 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q00657
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Cspg4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Cspg4 recombinant protein

   A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
NCBI/Uniprot data below describe general gene information for Cspg4. It may not necessarily be applicable to this product.
 NCBI GI #    13591932
 NCBI GeneID    81651
 NCBI Accession #    NP_112284.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_031022.1 [Other Products]
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 UniProt Primary Accession #    Q00657 [Other Products]
 UniProt Related Accession #    Q00657 [Other Products]
 Molecular Weight    251,909 Da
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 NCBI Official Full Name    chondroitin sulfate proteoglycan 4
 NCBI Official Synonym Full Names    chondroitin sulfate proteoglycan 4
 NCBI Official Symbol    Cspg4 [Similar Products]
 NCBI Official Synonym Symbols   
Ng2
[Similar Products]
 NCBI Protein Information    chondroitin sulfate proteoglycan 4
 UniProt Protein Name    Chondroitin sulfate proteoglycan 4
 UniProt Synonym Protein Names   
Chondroitin sulfate proteoglycan NG2; HSN tumor-specific antigen
 Protein Family    Chondroitin sulfate proteoglycan
 UniProt Gene Name    Cspg4 [Similar Products]
 UniProt Synonym Gene Names    Ng2 [Similar Products]
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 NCBI Summary for Cspg4    extracellular matrix protein secreted by many cell types; member of the large chondroitin sulfate proteoglycan (CSPG) family; may be involved with angiogenesis -dependent processes such as wound healing or tumor growth [RGD, Feb 2006]
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 UniProt Comments for Cspg4    Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.
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 Research Articles on Cspg4    1. chondroitin sulfate proteoglycan 4 (CSPG4) is a potential mesenchymal progenitor cells marker.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Cspg4 recombinant proteinPathways associated with Cspg4 recombinant protein
 Reference Product  PubMed Publications
 Dcn recombinant protein  >1 publications with Cspg4 and Dcn
 Bgn recombinant protein  >1 publications with Cspg4 and Bgn
 Chst11 recombinant protein  >1 publications with Cspg4 and Chst11
 Products by Pathway  Pathway Diagram
 A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway antibodies  A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway Diagram
 CS/DS Degradation Pathway antibodies  CS/DS Degradation Pathway Diagram
 Chondroitin Sulfate Biosynthesis Pathway antibodies  Chondroitin Sulfate Biosynthesis Pathway Diagram
 Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies  Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
 Dermatan Sulfate Biosynthesis Pathway antibodies  Dermatan Sulfate Biosynthesis Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway antibodies  Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
Diseases associated with Cspg4 recombinant proteinOrgans/Tissues associated with Cspg4 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >24 publications with Cspg4 and Neoplasms
 Skin Diseases Antibodies  >11 publications with Cspg4 and Skin Diseases
 Skin Neoplasms Antibodies  >5 publications with Cspg4 and Skin Neoplasms
 Lung Neoplasms Antibodies  >4 publications with Cspg4 and Lung Neoplasms
 Breast Neoplasms Antibodies  >4 publications with Cspg4 and Breast Neoplasms
 Glioma Antibodies  >4 publications with Cspg4 and Glioma
 Neoplasm Metastasis Antibodies  >3 publications with Cspg4 and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >3 publications with Cspg4 and Neoplasms, Experimental
 Carcinoma Antibodies  >2 publications with Cspg4 and Carcinoma
 Cerebral Infarction Antibodies  >2 publications with Cspg4 and Cerebral Infarction
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with Cspg4 and Brain
 Connective Tissue Antibodies  >2 publications with Cspg4 and Connective Tissue
 Artery Antibodies  >1 publications with Cspg4 and Artery
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