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Add To Compare List F11 recombinant protein :: Coagulation factor XI (F11) Recombinant Protein Catalog # MBS1377802 Unit / Price 0.02 mg (E-Coli) / $920 +1 FREE 8GB USB 0.02 mg (Yeast) / $1,045 +1 FREE 8GB USB 0.1 mg (E-Coli) / $1,100 +1 FREE 8GB USB 0.1 mg (Yeast) / $1,185 +1 FREE 8GB USB 0.02 mg (Baculovirus) / $1,250 +1 FREE 8GB USB 0.02 mg (Mammalian-Cell) / $1,520 +1 FREE 8GB USB 0.1 mg (Baculovirus) / $1,795 +2 FREE 8GB USB 1 mg (E-Coli) / $1,960 +2 FREE 8GB USB 1 mg (Yeast) / $2,345 +2 FREE 8GB USB 0.1 mg (Mammalian-Cell) / $2,380 +2 FREE 8GB USB 1 mg (Baculovirus) / $3,490 +4 FREE 8GB USB 0.5 mg (Mammalian-Cell) / $6,070 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Coagulation factor XI (F11), Recombinant Protein Full Product Name Recombinant Mouse Coagulation factor XI (F11) Product Gene Name F11 recombinant protein[Similar Products] Product Synonym Gene Name F11[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 19-389. Partial (Coagulation factor XIa heavy chain) Sequence ECVTKVFKDI SFQGGDLSTV FTPSATYCRL VCTHHPRCLL FTFMAESSSD DPTKWFACIL KDSVTEILPM VNMTGAISGY SFKQCPQQLS TCSKDVYVNL DMKGMNYNSS VVKNARECQE RCTDDAHCQF FTYATGYFPS VDHRKMCLLK YTRTGTPTTI TKLNGVVSGF SLKSCGLSNL ACIRDIFPNT VLADLNIDSV VAPDAFVCRR ICTHHPTCLF FTFFSQAWPK ESQRHLCLLK TSESGLPSTR ITKSHALSGF SLQHCRHSVP VFCHPSFYND TDFLGEELDI VDVKGQETCQ KTCTNNARCQ FFTYYPSHRL CNERNRRGRC YLKLSSNGSP TRILHGRGGI SGYSLRLCKM DNVCTTKINP R 3D Structure ModBase 3D Structure for Q91Y47 Host E Coli or Yeast or Baculovirus or Mammalian Cell Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized or liquid (Format to be determined during the manufacturing process) Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Species Mouse Preparation and Storage Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of F11 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for F11 recombinant protein This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. NCBI/Uniprot data below describe general gene information for F11. It may not necessarily be applicable to this product. NCBI GI # 21312500 NCBI GeneID 109821 NCBI Accession # NP_082342.1 [Other Products] NCBI GenBank Nucleotide # NM_028066.2 [Other Products] UniProt Primary Accession # Q91Y47 [Other Products] UniProt Secondary Accession # Q9DAT3[Other Products] UniProt Related Accession # Q91Y47[Other Products] Molecular Weight 69,789 Da TOP NCBI Official Full Name coagulation factor XI preproprotein NCBI Official Synonym Full Names coagulation factor XI NCBI Official Symbol F11 [Similar Products] NCBI Official Synonym Symbols FXI; PTA; Cf11; AI503996; 1600027G01Rik [Similar Products] NCBI Protein Information coagulation factor XI UniProt Protein Name Coagulation factor XI UniProt Synonym Protein Names Plasma thromboplastin antecedent; PTA Protein Family Coagulation factor UniProt Gene Name F11 [Similar Products] UniProt Synonym Gene Names FXI; PTA [Similar Products] TOP NCBI Summary for F11 This gene encodes a glycoprotein coagulation factor that plays an important role in intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that can be activated by coagulation factor XIIa, thrombin or factor XIa to generate active factor XIa protease. Mice lacking the encoded protein display a survival advantage during peritoneal sepsis and resist inflammation and bacterial accumulation upon infection with Listeria. [provided by RefSeq, Apr 2015] TOP UniProt Comments for F11 Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. Research Articles on F11 1. FXI attenuates part of the allergic response to repeated administration of house dust mite in the airways by a mechanism that is independent of activation via FXII. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with F11 recombinant protein Reference Product PubMed Publications F12 recombinant protein >31 publications with F11 and F12 Klkb1 recombinant protein >8 publications with F11 and Klkb1 Serpinc1 recombinant protein >4 publications with F11 and Serpinc1 Kng1 recombinant protein >3 publications with F11 and Kng1 Pathways associated with F11 recombinant protein Products by Pathway Pathway Diagram Blood Clotting Cascade Pathway antibodies Blood Clotting Cascade Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram Hemostasis Pathway antibodies Hemostasis Pathway Diagram Intrinsic Pathway antibodies Intrinsic Pathway Diagram Diseases associated with F11 recombinant protein Disease Name Pubmed Publications Neoplasms Antibodies >60 publications with F11 and Neoplasms Nervous System Diseases Antibodies >48 publications with F11 and Nervous System Diseases Cardiovascular Diseases Antibodies >38 publications with F11 and Cardiovascular Diseases Vascular Diseases Antibodies >34 publications with F11 and Vascular Diseases Hematologic Diseases Antibodies >31 publications with F11 and Hematologic Diseases Brain Diseases Antibodies >27 publications with F11 and Brain Diseases Thrombosis Antibodies >26 publications with F11 and Thrombosis Factor XI Deficiency Antibodies >26 publications with F11 and Factor XI Deficiency Inflammation Antibodies >25 publications with F11 and Inflammation Blood Coagulation Disorders Antibodies >24 publications with F11 and Blood Coagulation Disorders Organs/Tissues associated with F11 recombinant protein Organ/Tissue Name Pubmed Publications Muscle Antibodies >35 publications with F11 and Muscle Embryonic Tissue Antibodies >28 publications with F11 and Embryonic Tissue Eye Antibodies >23 publications with F11 and Eye Liver Antibodies >14 publications with F11 and Liver Extraembryonic Tissue Antibodies >1 publications with F11 and Extraembryonic Tissue TOP © 2006-24 MyBioSource.com. 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