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F13A1 recombinant protein :: Coagulation factor XIII A chain (F13A1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS966620 F13A1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $555 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $745 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $820 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $870 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $965 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,085 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,090 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,105 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,155 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,580 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,645 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,685 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,115 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Coagulation factor XIII A chain (F13A1), Recombinant Protein

 Also Known As   

Recombinant Bovine Coagulation factor XIII A chain (F13A1)

 Product Gene Name   

F13A1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    39-198aa, Full Length of Mature Protein
 Sequence    GFNPQDYLNV TNVHLFKERW DSNKVDHHTD KYSNDKLIVR RGQSFYIQID FNRPYDPTRD LFRVEYVIGL YPQENKGTYI PVPLVSELQS GKWGAKVVMR EDRSVRLSVQ SSADCIVGKF RMYVAVWTPY GVIRTSRNPE TDTYILFNPW CEEDAVYLEN
 3D Structure    ModBase 3D Structure for P12260
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Bovine
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of F13A1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for F13A1 recombinant protein

   This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.
NCBI/Uniprot data below describe general gene information for F13A1. It may not necessarily be applicable to this product.
 NCBI GI #    206729861
 NCBI GeneID    617881
 NCBI Accession #    P12260.2 [Other Products]
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 UniProt Primary Accession #    P12260 [Other Products]
 UniProt Secondary Accession #    Q1JPK3 [Other Products]
 UniProt Related Accession #    P12260 [Other Products]
 Molecular Weight    22,745 Da
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 NCBI Official Full Name    Coagulation factor XIII A chain
 NCBI Official Synonym Full Names    coagulation factor XIII A chain
 NCBI Official Symbol    F13A1 [Similar Products]
 NCBI Protein Information    coagulation factor XIII A chain
 UniProt Protein Name    Coagulation factor XIII A chain
 UniProt Synonym Protein Names   
Protein-glutamine gamma-glutamyltransferase A chain; Transglutaminase A chain
 Protein Family    Coagulation factor
 UniProt Gene Name    F13A1 [Similar Products]
 UniProt Synonym Gene Names    F13A; Coagulation factor XIIIa [Similar Products]
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 UniProt Comments for F13A1    Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
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 Research Articles on F13A1    1. kinetic and structural analysis of interactions between thrombin and the Factor XIII activation peptide
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with F13A1 recombinant proteinPathways associated with F13A1 recombinant protein
 Reference Product  PubMed Publications
 FGA recombinant protein  >10 publications with F13A1 and FGA
 F13B recombinant protein  >10 publications with F13A1 and F13B
 FGB recombinant protein  >5 publications with F13A1 and FGB
 FGG recombinant protein  >4 publications with F13A1 and FGG
 TGFB3 recombinant protein  >2 publications with F13A1 and TGFB3
 Products by Pathway  Pathway Diagram
 Common Pathway Of Fibrin Clot Formation antibodies  Common Pathway Of Fibrin Clot Formation Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Platelet Degranulation Pathway antibodies  Platelet Degranulation Pathway Diagram
 Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies  Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram
Organs/Tissues associated with F13A1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >41 publications with F13A1 and Blood
 Skin Antibodies  >4 publications with F13A1 and Skin
 Adipose Tissue Antibodies  >3 publications with F13A1 and Adipose Tissue
 Cartilage Antibodies  >1 publications with F13A1 and Cartilage
 Ovary Antibodies  >1 publications with F13A1 and Ovary
 Muscle Antibodies  >1 publications with F13A1 and Muscle
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