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Add To Compare List Col7a1 recombinant protein :: Collagen alpha-1 (VII) chain (Col7a1) Recombinant Protein Catalog # MBS1315735 Unit / Price 0.5 mg (E-Coli) / $1,110 +1 FREE 8GB USB 0.05 mg (Baculovirus) / $1,110 +1 FREE 8GB USB 0.5 mg (Yeast) / $1,330 +1 FREE 8GB USB 0.05 mg (Mammalian-Cell) / $1,330 +1 FREE 8GB USB 1 mg (E-Coli) / $1,555 +1 FREE 8GB USB 0.1 mg (Baculovirus) / $1,555 +1 FREE 8GB USB 1 mg (Yeast) / $2,060 +2 FREE 8GB USB 0.1 mg (Mammalian-Cell) / $2,060 +2 FREE 8GB USB 0.5 mg (Baculovirus) / $2,100 +2 FREE 8GB USB 1 mg (Baculovirus) / $2,950 +3 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Collagen alpha-1 (VII) chain (Col7a1), Recombinant Protein Full Product Name Recombinant Mouse Collagen alpha-1 (VII) chain (Col7a1) , partial Product Gene Name Col7a1 recombinant protein[Similar Products] Product Synonym Gene Name Col7a1[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 39-212, partial, Provide the VWFA1 domain Sequence DIVFLLDGSS SIGRSNFREV RGFLEGLVLP FSGAASAQGV RFATVQYSDD PQTEFGLDTL GSGSDTIRAI RELSYKGGNT RTGAALHHVS DRVFLPRLTR PGVPKVCILI TDGKSQDLVD TAAQKLKGQG VKLFAVGIKN ADPEELKRVA SQPTSDFFFF VNDFSILRTL LPLI 3D Structure ModBase 3D Structure for Q63870 Host E Coli or Yeast or Baculovirus or Mammalian Cell Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized or liquid (Format to be determined during the manufacturing process) Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Species Mouse Preparation and Storage Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of Col7a1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for Col7a1 recombinant protein This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. NCBI/Uniprot data below describe general gene information for Col7a1. It may not necessarily be applicable to this product. NCBI GI # 115647999 NCBI GeneID 12836 NCBI Accession # NP_031764.2 [Other Products] NCBI GenBank Nucleotide # NM_007738.3 [Other Products] UniProt Primary Accession # Q63870 [Other Products] UniProt Secondary Accession # Q78EC6[Other Products] UniProt Related Accession # Q63870[Other Products] Molecular Weight 295,232 Da TOP NCBI Official Full Name collagen alpha-1(VII) chain NCBI Official Synonym Full Names collagen, type VII, alpha 1 NCBI Official Symbol Col7a1 [Similar Products] NCBI Official Synonym Symbols AW209154 [Similar Products] NCBI Protein Information collagen alpha-1(VII) chain UniProt Protein Name Collagen alpha-1(VII) chain UniProt Synonym Protein Names Long-chain collagen; LC collagen UniProt Gene Name Col7a1 [Similar Products] UniProt Synonym Gene Names LC collagen [Similar Products] TOP TOP UniProt Comments for Col7a1 Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. Research Articles on Col7a1 1. miR-29 Regulates COL7A1 in Recessive Dystrophic Epidermolysis Bullosa, directly through targeting its 3' untranslated region at two distinct seed regions and indirectly through targeting an essential transcription factor required for basal COL7A1 expression, SP1 TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with Col7a1 recombinant protein Reference Product PubMed Publications Col1a1 recombinant protein >8 publications with Col7a1 and Col1a1 Col3a1 recombinant protein >7 publications with Col7a1 and Col3a1 Lamb3 recombinant protein >7 publications with Col7a1 and Lamb3 Col8a1 recombinant protein >3 publications with Col7a1 and Col8a1 Lama3 recombinant protein >3 publications with Col7a1 and Lama3 Lamc2 recombinant protein >3 publications with Col7a1 and Lamc2 Col5a1 recombinant protein >2 publications with Col7a1 and Col5a1 Col4a5 recombinant protein >2 publications with Col7a1 and Col4a5 Tll1 recombinant protein >1 publications with Col7a1 and Tll1 Bmp1 recombinant protein >1 publications with Col7a1 and Bmp1 Pathways associated with Col7a1 recombinant protein Products by Pathway Pathway Diagram Anchoring Fibril Formation Pathway antibodies Anchoring Fibril Formation Pathway Diagram Asparagine N-linked Glycosylation Pathway antibodies Asparagine N-linked Glycosylation Pathway Diagram Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram COPII (Coat Protein 2) Mediated Vesicle Transport Pathway antibodies COPII (Coat Protein 2) Mediated Vesicle Transport Pathway Diagram Cargo Concentration In The ER Pathway antibodies Cargo Concentration In The ER Pathway Diagram Collagen Biosynthesis And Modifying Enzymes Pathway antibodies Collagen Biosynthesis And Modifying Enzymes Pathway Diagram Collagen Chain Trimerization Pathway antibodies Collagen Chain Trimerization Pathway Diagram Collagen Formation Pathway antibodies Collagen Formation Pathway Diagram ER To Golgi Anterograde Transport Pathway antibodies ER To Golgi Anterograde Transport Pathway Diagram Extracellular Matrix Organization Pathway antibodies Extracellular Matrix Organization Pathway Diagram Diseases associated with Col7a1 recombinant protein Disease Name Pubmed Publications Epidermolysis Bullosa Dystrophica Antibodies >309 publications with Col7a1 and Epidermolysis Bullosa Dystrophica Epidermolysis Bullosa Pruriginosa Antibodies >35 publications with Col7a1 and Epidermolysis Bullosa Pruriginosa Pruritus Antibodies >22 publications with Col7a1 and Pruritus Fibrosis Antibodies >9 publications with Col7a1 and Fibrosis Inflammation Antibodies >6 publications with Col7a1 and Inflammation Transient bullous dermolysis of the newborn Antibodies >5 publications with Col7a1 and Transient bullous dermolysis of the newborn Cell Transformation, Neoplastic Antibodies >4 publications with Col7a1 and Cell Transformation, Neoplastic Nervous System Diseases Antibodies >4 publications with Col7a1 and Nervous System Diseases Necrosis Antibodies >3 publications with Col7a1 and Necrosis Neoplasms, Experimental Antibodies >2 publications with Col7a1 and Neoplasms, Experimental Organs/Tissues associated with Col7a1 recombinant protein Organ/Tissue Name Pubmed Publications Skin Antibodies >243 publications with Col7a1 and Skin Embryonic Tissue Antibodies >3 publications with Col7a1 and Embryonic Tissue Brain Antibodies >2 publications with Col7a1 and Brain Liver Antibodies >1 publications with Col7a1 and Liver Inner Ear Antibodies >1 publications with Col7a1 and Inner Ear Eye Antibodies >1 publications with Col7a1 and Eye Kidney Antibodies >1 publications with Col7a1 and Kidney TOP © 2006-24 MyBioSource.com. 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