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COL17A1 recombinant protein :: Collagen alpha-1 (XVII) chain (COL17A1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1265558
SDS-Page
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.3 mg (E-Coli)  /  $580 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $705 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $855 +1 FREE 8GB USB
0.1 mg (Yeast)  /  $925 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $950 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,070 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,080 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,095 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,565 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,620 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,670 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,090 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Collagen alpha-1 (XVII) chain (COL17A1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Collagen alpha-1 (XVII) chain (COL17A1) , partial

 Product Gene Name   

COL17A1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    COL17A1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1253-1497. Partial
 Sequence    YLTSPDVRSF IVGPPGPPGP QGPPGDSRLL STDASHSRGS SSSSHSSSVR RGSSYSSSMS TGGGGAGSLG AGGAFGEAAG DRGPYGTDIG PGGGYGAAAE GGMYAGNGGL LGADFAGDLD YNELAVRVSE SMQRQGLLQG MAYTVQGPPG QPGPQGPPGI SKVFSAYSNV TADLMDFFQT YGAIQGPPGQ KGEMGTPGPK GDRGPAGPPG HPGPPGPRGH KGEKGDKGDQ VYAGRRRRRS IAVKP
 OMIM    113811
 3D Structure    ModBase 3D Structure for Q9UMD9
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of COL17A1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for COL17A1 recombinant protein

   This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.
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 SDS-Page of COL17A1 recombinant protein    COL17A1 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for COL17A1. It may not necessarily be applicable to this product.
 NCBI GI #    119829187
 NCBI GeneID    1308
 NCBI Accession #    NP_000485.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_000494.3 [Other Products]
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 UniProt Primary Accession #    Q9UMD9 [Other Products]
 UniProt Secondary Accession #    Q02802; Q5JV36; Q99018; Q9NQK9; Q9UC14 [Other Products]
 UniProt Related Accession #    Q9UMD9 [Other Products]
 Molecular Weight    142,344 Da
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 NCBI Official Full Name    collagen alpha-1(XVII) chain
 NCBI Official Synonym Full Names    collagen type XVII alpha 1 chain
 NCBI Official Symbol    COL17A1 [Similar Products]
 NCBI Official Synonym Symbols   
ERED; BP180; BPA-2; BPAG2; LAD-1; BA16H23.2
[Similar Products]
 NCBI Protein Information    collagen alpha-1(XVII) chain
 UniProt Protein Name    Collagen alpha-1(XVII) chain
 UniProt Synonym Protein Names   
180 kDa bullous pemphigoid antigen 2; Bullous pemphigoid antigen 2
 UniProt Gene Name    COL17A1 [Similar Products]
 UniProt Synonym Gene Names    BP180; BPAG2; LAD-1; 97 kDa LAD antigen; 97-LAD; LABD97 [Similar Products]
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 NCBI Summary for COL17A1    This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]
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 UniProt Comments for COL17A1    May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.
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 Research Articles on COL17A1    1. C-terminal processing induces dynamic structural changes and neoepitopes for linear IgA dermatosis autoantibodies on COL17
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with COL17A1 recombinant proteinPathways associated with COL17A1 recombinant protein
 Reference Product  PubMed Publications
 DST recombinant protein  >17 publications with COL17A1 and DST
 LAMB3 recombinant protein  >15 publications with COL17A1 and LAMB3
 LAMC2 recombinant protein  >9 publications with COL17A1 and LAMC2
 ITGB4 recombinant protein  >6 publications with COL17A1 and ITGB4
 COL7A1 recombinant protein  >5 publications with COL17A1 and COL7A1
 PLEC recombinant protein  >1 publications with COL17A1 and PLEC
 Products by Pathway  Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Degradation Pathway antibodies  Collagen Degradation Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
Diseases associated with COL17A1 recombinant proteinOrgans/Tissues associated with COL17A1 recombinant protein
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >49 publications with COL17A1 and Congenital Abnormalities
 Carcinoma, Squamous Cell Antibodies  >8 publications with COL17A1 and Carcinoma, Squamous Cell
 Neoplasms Antibodies  >5 publications with COL17A1 and Neoplasms
 Hyperplasia Antibodies  >2 publications with COL17A1 and Hyperplasia
 Melanoma Antibodies  >1 publications with COL17A1 and Melanoma
 Fetal Death Antibodies  >1 publications with COL17A1 and Fetal Death
 Nervous System Malformations Antibodies  >1 publications with COL17A1 and Nervous System Malformations
 Cell Transformation, Neoplastic Antibodies  >1 publications with COL17A1 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Mouth Antibodies  >3 publications with COL17A1 and Mouth
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