NP_001333779.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
76,684 Da
NCBI Official Full Name
complement C1s subcomponent isoform 2
NCBI Official Synonym Full Names
complement C1s
NCBI Official Synonym Symbols
NCBI Protein Information
complement C1s subcomponent
UniProt Protein Name
Complement C1s subcomponent
UniProt Synonym Protein Names
C1 esterase; Complement component 1 subcomponent s
NCBI Summary for C1S
This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]
UniProt Comments for C1S
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
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Products associated with C1S recombinant protein
Pathways associated with C1S recombinant protein
Diseases associated with C1S recombinant protein
Organs/Tissues associated with C1S recombinant protein
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