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CCNB2 recombinant protein :: Cyclin-B2 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS145143 CCNB2 recombinant protein
Unit / Price
0.002 mg  /  $140 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $5,015 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cyclin-B2 (CCNB2), Recombinant Protein

 Also Known As   

Recombinant Human Cyclin-B2

 Product Synonym Names    CCNB2 Human; Cyclin-B2 Human Recombinant; G2/mitotic-specific cyclin-B2; HsT17299; cyclin B2
 Product Gene Name   

CCNB2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHH HHH SSGLVPRGSH MGSHMA LLRR PTVSSDLENI DTGVNSKVKS HVTIRRTVLE EIGNRVTTRA AQVAKKAQNT KVPVQPTKTT NVNKQLKPTA SVKPVQMEKL APKGPSPTPE DVSMKEENLC QAFSDALLCK IEDIDNEDWE NPQLCSDYVK DIYQYLRQLE VLQSINPHFL DGRDINGRMR AILVDWLVQV HSKFRLLQET LYMCVGIMDR FLQVQPVSRK KLQLVGITAL LLASKYEEMF SPNIEDFVYI TDNAYTSSQI REMETLILKE LKFELGRPLP LHFLRRASKA GEVDVEQHTL AKYLMELTLI DYDMVHYHPS KVAAAASCLS QKVLGQGKWN LKQQYYTGYT ENEVLEVMQH MAKNVVKVNE NLTKFIAIKN KYASSKLLKI SMIPQLNSKA VKDLASPLIG RSc
 OMIM    602755
 3D Structure    ModBase 3D Structure for O95067
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 Host    E Coli
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE.
 Form/Format    The CCNB2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 5mM DTT and 50% glycerol.
Sterile Filtered colorless solution.
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 Other Notes    Small volumes of CCNB2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CCNB2 recombinant protein

   Description: CCNB2 Human Recombinant produced in E Coli is a single polypeptide chain containing 422 amino acids (1-398) and having a molecular mass of 47.9 kDa.CCNB2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: CCNB2 is a member of the cyclin family. CCNB2 is vital for regulation of the cell cycle at the G2/M (mitosis) transition. CCNB2 cooperates with the CDK1 protein kinase to create a serine/threonine kinase holoenzyme complex recognized as maturation promoting factor (MPF).
 Product Categories/Family for CCNB2 recombinant protein    PROTEIN KINASES; Enzymes; Cyclin
NCBI/Uniprot data below describe general gene information for CCNB2. It may not necessarily be applicable to this product.
 NCBI GI #    4757930
 NCBI GeneID    9133
 NCBI Accession #    NP_004692.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004701.3 [Other Products]
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 UniProt Primary Accession #    O95067 [Other Products]
 UniProt Secondary Accession #    Q6FI99; B3KM93 [Other Products]
 UniProt Related Accession #    O95067 [Other Products]
 Molecular Weight    45,282 Da
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 NCBI Official Full Name    G2/mitotic-specific cyclin-B2
 NCBI Official Synonym Full Names    cyclin B2
 NCBI Official Symbol    CCNB2 [Similar Products]
 NCBI Official Synonym Symbols   
HsT17299
[Similar Products]
 NCBI Protein Information    G2/mitotic-specific cyclin-B2
 UniProt Protein Name    G2/mitotic-specific cyclin-B2
 Protein Family    Cyclin
 UniProt Gene Name    CCNB2 [Similar Products]
 UniProt Entry Name    CCNB2_HUMAN
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 NCBI Summary for CCNB2    Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CCNB2    CCNB2: Essential for the control of the cell cycle at the G2/M (mitosis) transition. Belongs to the cyclin family. Cyclin AB subfamily.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 15q22.2

Cellular Component: nucleoplasm; microtubule cytoskeleton; centrosome; membrane; cytosol

Molecular Function: protein binding; protein kinase binding

Biological Process: mitosis; thymus development; regulation of cell cycle; cell division; in utero embryonic development; mitotic nuclear envelope disassembly; T cell homeostasis; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; growth
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 Research Articles on CCNB2    1. Cyclin B1 and cyclin B2 are interchangeable for ability to promote G2 and M transition in HeLa cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CCNB2 recombinant proteinPathways associated with CCNB2 recombinant protein
 Reference Product  PubMed Publications
 CCNB1 recombinant protein  >142 publications with CCNB2 and CCNB1
 CDK1 recombinant protein  >37 publications with CCNB2 and CDK1
 CDC25C recombinant protein  >22 publications with CCNB2 and CDC25C
 CDK2 recombinant protein  >21 publications with CCNB2 and CDK2
 CDC20 recombinant protein  >14 publications with CCNB2 and CDC20
 FOXM1 recombinant protein  >7 publications with CCNB2 and FOXM1
 BUB1 recombinant protein  >6 publications with CCNB2 and BUB1
 PLK1 recombinant protein  >6 publications with CCNB2 and PLK1
 CDC6 recombinant protein  >4 publications with CCNB2 and CDC6
 MCM2 recombinant protein  >4 publications with CCNB2 and MCM2
 Products by Pathway  Pathway Diagram
 Activation Of NIMA Kinases NEK9, NEK6, NEK7 Pathway antibodies  Activation Of NIMA Kinases NEK9, NEK6, NEK7 Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle - G2/M Transition Pathway antibodies  Cell Cycle - G2/M Transition Pathway Diagram
 Cell Cycle - G2/M Transition Pathway antibodies  Cell Cycle - G2/M Transition Pathway Diagram
 Condensation Of Prometaphase Chromosomes Pathway antibodies  Condensation Of Prometaphase Chromosomes Pathway Diagram
Diseases associated with CCNB2 recombinant proteinOrgans/Tissues associated with CCNB2 recombinant protein
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >31 publications with CCNB2 and Adenocarcinoma
 Breast Neoplasms Antibodies  >27 publications with CCNB2 and Breast Neoplasms
 Lung Diseases Antibodies  >18 publications with CCNB2 and Lung Diseases
 Lung Neoplasms Antibodies  >17 publications with CCNB2 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >12 publications with CCNB2 and Neoplasms, Experimental
 Neoplasm Metastasis Antibodies  >9 publications with CCNB2 and Neoplasm Metastasis
 Ovarian Neoplasms Antibodies  >9 publications with CCNB2 and Ovarian Neoplasms
 Disease Models, Animal Antibodies  >9 publications with CCNB2 and Disease Models, Animal
 Nervous System Diseases Antibodies  >8 publications with CCNB2 and Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >7 publications with CCNB2 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >25 publications with CCNB2 and Lung
 Blood Antibodies  >19 publications with CCNB2 and Blood
 Bone Antibodies  >15 publications with CCNB2 and Bone
 Liver Antibodies  >15 publications with CCNB2 and Liver
 Testis Antibodies  >13 publications with CCNB2 and Testis
 Vascular Antibodies  >10 publications with CCNB2 and Vascular
 Prostate Antibodies  >10 publications with CCNB2 and Prostate
 Bone Marrow Antibodies  >10 publications with CCNB2 and Bone Marrow
 Embryonic Tissue Antibodies  >9 publications with CCNB2 and Embryonic Tissue
 Ovary Antibodies  >8 publications with CCNB2 and Ovary
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