Q6SLL5.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
22,117 Da
NCBI Official Full Name
Cyclin-dependent kinase inhibitor 1B
NCBI Official Synonym Full Names
cyclin dependent kinase inhibitor 1B
NCBI Protein Information
cyclin-dependent kinase inhibitor 1B
UniProt Protein Name
Cyclin-dependent kinase inhibitor 1B
UniProt Synonym Protein Names
Cyclin-dependent kinase inhibitor p27; p27Kip1
UniProt Synonym Gene Names
UniProt Comments for CDKN1B
Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Research Articles on CDKN1B
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Pathways associated with CDKN1B recombinant protein
Diseases associated with CDKN1B recombinant protein
Organs/Tissues associated with CDKN1B recombinant protein
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