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cypA recombinant protein :: Cypemycin (cypA) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1155741 cypA recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $410 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $545 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $595 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $600 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $760 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $805 +1 FREE 8GB USB
1 mg (E-Coli)  /  $845 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $910 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $960 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $995 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,370 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,390 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,525 +1 FREE 8GB USB
1 mg (Baculovirus)  /  $1,870 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cypemycin (cypA), Recombinant Protein

 Also Known As   

Recombinant Cypemycin (cypA)

 Product Synonym Names    Recombinant Cypemycin (cypA); Cypemycin
 Product Gene Name   

cypA recombinant protein

[Similar Products]
 Product Synonym Gene Name    cypA [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    43-64aa; Cytoplasmic domain
 Sequence    ATPATPTV AQFVIQGSTI CLVC
 3D Structure    ModBase 3D Structure for E5KIB6
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Streptomyces sp.
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of cypA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for cypA. It may not necessarily be applicable to this product.
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 UniProt Primary Accession #    E5KIB6 [Other Products]
 Molecular Weight    6,533 Da [Similar Products]
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 UniProt Protein Name    Cypemycin
 Protein Family    Cypemycin
 UniProt Gene Name    cypA [Similar Products]
 UniProt Entry Name    CYPA_STRSQ
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 UniProt Comments for cypA    Function: Antibiotic peptide structurally related to lantibiotics. Active against M.luteus (MIC=0.2 µg/ml). Has cytotoxic activity against mouse P388 leukemia cells (IC50=1.3 µg/ml). Ref.1 Ref.2

Subcellular location: Secreted. Secreted › extracellular space Ref.2.

Post-translational modification: Maturation involves the enzymatic conversion of Cys-61 into 2,3-didehydroalanine followed by formation of a thioether bond with Cys-64. The C-terminal meso-lanthionine then undergoes decarboxylation. Ref.3Dimethylated at the N-terminus. Dimethylation is required for antibiotic activity. Ref.1 Ref.3The configuration of reformed Cys-61 as the D form was attributed by similarity to related structures. Ref.1

Sequence similarities: Belongs to the linaridin family. Ref.1

Mass spectrometry: Molecular mass is 2094 Da from positions 43 - 64. Determined by FAB. Ref.3Molecular mass is 2096 Da from positions 43 - 64. Determined by MALDI. Ref.1
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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