C8ZFZ7.2
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UniProt Primary Accession #
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[Other Products]
Molecular Weight
52,089 Da
NCBI Official Full Name
Cysteine proteinase 1, mitochondrial
UniProt Protein Name
Cysteine proteinase 1, mitochondrial
UniProt Synonym Protein Names
Bleomycin hydrolase; BLM hydrolase; Homocysteine-thiolactonase; HTLase; Hcy-thiolactonase; Leucine aminopeptidase 3; Y3
UniProt Synonym Gene Names
UniProt Comments for LAP3
The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities ().
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