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CMPK1 recombinant protein :: Cytidine Monophosphate Kinase 1 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS144635 CMPK1 recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $3,515 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cytidine Monophosphate Kinase 1 (CMPK1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Cytidine Monophosphate Kinase 1

 Product Synonym Names    CMPK1 Human; Cytidine Monophosphate Kinase 1 Human Recombinant; UMP-CMP kinase; Cytidine monophosphate kinase; Cytidylate kinase; Deoxycytidylate kinase; Uridine monophosphate kinase; Uridine monophosphate/cytidine monophosphate kinase; UMP/CMP kinase; UMP/CMPK; CMPK1; CMK; CMPK; UCK; UMK; UMPK; UMP-CMPK; RP11-511I2.1
 Product Gene Name   

CMPK1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MLSRCRSGLL HVLGLSFLLQ TRRPILLCSP RLMKPLVVFV LGGPGAGKGT QCARIVEKYG YTHLSAGELL RDERKNPDSQ YGELIEKYIK EGKIVPVEIT ISLLKREMDQ TMAANAQKNK FLIDGFPRNQ DNLQGWNKTM DGKADVSFVL FFDCNNEICI ERCLERGKSS GRSDDNRESL EKRIQTYLQS TKPIIDLYEE MGKVKKIDAS KSVDEVFDEV VQIFDKEG.
 OMIM    191710
 3D Structure    ModBase 3D Structure for P30085
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 Host    E Coli
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 Purity/Purification    Greater than 90.0% as determined by SDS-PAGE.
 Form/Format    CMPK1 solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 1mM DTT and 100mM NaCl.
Sterile filtered colorless solution.
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 Preparation and Storage    Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
 Other Notes    Small volumes of CMPK1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for CMPK1 recombinant protein

   Description: CMPK1 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 248 amino acids (1-228) and having a molecular mass of 28kDa. CMPK1 is fused to a 20 a.a His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Introduction: UMP-CMP kinase and deoxycytidylate kinase (CMPK1) is an enzyme which catalyzes the phosphoryl transfer from ATP to UMP, CMP and dCMP. This enzymatic reaction brings about the formation of ADP and the corresponding nucleoside diphosphate that are necessary for cellular nucleic acid synthesis. In addition, CMPK1 has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs.
 Product Categories/Family for CMPK1 recombinant protein    PROTEIN KINASES; Enzymes; Protein Kinases
NCBI/Uniprot data below describe general gene information for CMPK1. It may not necessarily be applicable to this product.
 NCBI GI #    209915597
 NCBI GeneID    51727
 NCBI Accession #    NP_001129612.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001136140.1 [Other Products]
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 UniProt Primary Accession #    P30085 [Other Products]
 UniProt Secondary Accession #    Q53GB7; Q5SVZ0; Q96C07; Q9UBQ8; Q9UIA2; B4DPU7; E9PGI8 [Other Products]
 UniProt Related Accession #    P30085 [Other Products]
 Molecular Weight    16,548 Da
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 NCBI Official Full Name    UMP-CMP kinase isoform b
 NCBI Official Synonym Full Names    cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
 NCBI Official Symbol    CMPK1 [Similar Products]
 NCBI Official Synonym Symbols   
CK; CMK; UMK; CMPK; UMPK; UMP-CMPK
[Similar Products]
 NCBI Protein Information    UMP-CMP kinase; CK; CMPK1; UMP/CMP kinase; cytidylate kinase; dCMP kinase; deoxycytidylate kinase; nucleoside-diphosphate kinase; uridine monophosphate kinase; uridine monophosphate/cytidine monophosphate kinase
 UniProt Protein Name    UMP-CMP kinase
 UniProt Synonym Protein Names   
Deoxycytidylate kinase; Nucleoside-diphosphate kinase; Uridine monophosphate/cytidine monophosphate kinase
 UniProt Gene Name    CMPK1 [Similar Products]
 UniProt Entry Name    KCY_HUMAN
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 NCBI Summary for CMPK1    This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012]
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 UniProt Comments for CMPK1    CMPK: Catalyzes specific phosphoryl transfer from ATP to UMP and CMP. Belongs to the adenylate kinase family.

Protein type: EC 2.7.4.14; Nucleotide Metabolism - pyrimidine; Kinase, other; EC 2.7.4.6

Chromosomal Location of Human Ortholog: 1p32

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus; cytosol

Molecular Function: uridine kinase activity; UMP kinase activity; nucleoside diphosphate kinase activity; cytidylate kinase activity; ATP binding

Biological Process: nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside and nucleotide metabolic process; UMP biosynthetic process; phthalate metabolic process; pyrimidine ribonucleotide biosynthetic process; nucleoside diphosphate phosphorylation; UDP biosynthetic process; ovulation cycle process; 'de novo' pyrimidine base biosynthetic process; CDP biosynthetic process; dUDP biosynthetic process; nucleoside triphosphate biosynthetic process; dCDP biosynthetic process
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 Research Articles on CMPK1    1. In particular, polymorphisms of the CMPK1 gene seem to provide important prognostic information
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CMPK1 recombinant proteinPathways associated with CMPK1 recombinant protein
 Reference Product  PubMed Publications
 DCTD recombinant protein  >1 publications with CMPK1 and DCTD
 Products by Pathway  Pathway Diagram
 CMP Phosphorylation Pathway antibodies  CMP Phosphorylation Pathway Diagram
 CMP Phosphorylation Pathway antibodies  CMP Phosphorylation Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway antibodies  Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway Diagram
 Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway antibodies  Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway Diagram
 Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway antibodies  Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway Diagram
Diseases associated with CMPK1 recombinant proteinOrgans/Tissues associated with CMPK1 recombinant protein
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1 publications with CMPK1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >1 publications with CMPK1 and Eye
 Lung Antibodies  >1 publications with CMPK1 and Lung
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