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CSF2RB recombinant protein :: Cytokine receptor common subunit beta Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS206148
SDS-Page
Unit / Price
0.05 mg  /  $310 +1 FREE 8GB USB
0.25 mg  /  $925 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cytokine receptor common subunit beta (CSF2RB), Recombinant Protein

★Popular Item★
 Also Known As   

Cytokine receptor common subunit beta, 17-443aa, Human, His tag, Baculovirus

 Product Synonym Names    CD131; CDw131; IL3RB; IL5RB; SMDP5; CSF2RB
 Product Gene Name   

CSF2RB recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    WERSLAGAEE TIPLQTLRCY NDYTSHITCR WADTQDAQRL VNVTLIRRVN EDLLEPVSCD LSDDMPWSAC PHPRCVPRRC VIPCQSFVVT DVDYFSFQPD RPLGTRLTVT LTQHVQPPEP RDLQISTDQD HFLLTWSVAL GSPQSHWLSP GDLEFEVVYK RLQDSWEDAA ILLSNTSQAT LGPEHLMPSS TYVARVRTRL APGSRLSGRP SKWSPEVCWD SQPGDEAQPQ NLECFFDGAA VLSCSWEVRK EVASSVSFGL FYKPSPDAGE EECSPVLREG LGSLHTRHHC QIPVPDPATH GQYIVSVQPR RAEKHIKSSV NIQMAPPSLN VTKDGDSYSL RWETMKMRYE HIDHTFEIQY RKDTATWKDS KTETLQNAHS MALPALEPST RYWARVRVRT SRTGYNGIWS EWSEARSWDT ESVLPMWLEH HHHHH
 OMIM    M59941 mRNA
 3D Structure    ModBase 3D Structure for P32927
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 Host    Baculovirus
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 Purity/Purification    > 95% by SDS-PAGE
 Form/Format    Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.
 Concentration    0.5 mg/ml (determined by Absorbance at 280nm) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
 Endotoxin Level    < 1.0 EU per 1 microgram of protein (determined by LAL method)
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of CSF2RB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CSF2RB recombinant protein

   CSF2RB, also known as cytokine receptor common subunit beta, is a high affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. This unusual form of receptor assembly likely applies also to IL-3 and IL-5 receptors, providing a structural basis for understanding their mechanism of activation and for the development of therapeutics. Recombinant human CSF2RB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
 Product Categories/Family for CSF2RB recombinant protein    Immunology
 Applications Tested/Suitable for CSF2RB recombinant protein   

SDS-PAGE

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 SDS-Page of CSF2RB recombinant protein    CSF2RB recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for CSF2RB. It may not necessarily be applicable to this product.
 NCBI GI #    4559408
 NCBI GeneID    1439
 NCBI Accession #    NP_000386 [Other Products]
 NCBI GenBank Nucleotide #    NM_000395.2 [Other Products]
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 UniProt Primary Accession #    P32927 [Other Products]
 UniProt Secondary Accession #    Q5JZI1; Q6ICE0 [Other Products]
 UniProt Related Accession #    P32927 [Other Products]
 Molecular Weight    49.7kDa (435aa) 40-57kDa (SDS-PAGE under reducing conditions) [Similar Products]
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 NCBI Official Full Name    cytokine receptor common subunit beta
 NCBI Official Synonym Full Names    colony stimulating factor 2 receptor beta common subunit
 NCBI Official Symbol    CSF2RB [Similar Products]
 NCBI Official Synonym Symbols   
CD131; IL3RB; IL5RB; SMDP5; CDw131; betaGMR
[Similar Products]
 NCBI Protein Information    cytokine receptor common subunit beta
 UniProt Protein Name    Cytokine receptor common subunit beta
 UniProt Synonym Protein Names   
CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD_antigen: CD131
 Protein Family    Cytokine receptor
 UniProt Gene Name    CSF2RB [Similar Products]
 UniProt Synonym Gene Names    IL3RB; IL5RB [Similar Products]
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 NCBI Summary for CSF2RB    The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]
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 UniProt Comments for CSF2RB    High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
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Product References and Citations for CSF2RB recombinant protein

   Hansen G., et al. (2008) Cell. 134:496-507.; Mulhern TD., et al. (2000) J Mol Biol. 297:989-1001.
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 Research Articles on CSF2RB    1. SYK mediates the actions of EPO and GM-CSF and coordinates with TGF-beta in erythropoiesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CSF2RB recombinant proteinPathways associated with CSF2RB recombinant protein
 Reference Product  PubMed Publications
 CSF2RA recombinant protein  >10 publications with CSF2RB and CSF2RA
 IL3RA recombinant protein  >6 publications with CSF2RB and IL3RA
 LYN recombinant protein  >3 publications with CSF2RB and LYN
 JAK2 recombinant protein  >3 publications with CSF2RB and JAK2
 JAK1 recombinant protein  >1 publications with CSF2RB and JAK1
 STAT5A recombinant protein  >1 publications with CSF2RB and STAT5A
 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Defective CSF2RA Causes Pulmonary Surfactant Metabolism Dysfunction 4 (SMDP4) Pathway antibodies  Defective CSF2RA Causes Pulmonary Surfactant Metabolism Dysfunction 4 (SMDP4) Pathway Diagram
Diseases associated with CSF2RB recombinant proteinOrgans/Tissues associated with CSF2RB recombinant protein
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >11 publications with CSF2RB and Lung Diseases
 Disease Models, Animal Antibodies  >7 publications with CSF2RB and Disease Models, Animal
 Inflammation Antibodies  >5 publications with CSF2RB and Inflammation
 Death Antibodies  >4 publications with CSF2RB and Death
 Chromosome Aberrations Antibodies  >2 publications with CSF2RB and Chromosome Aberrations
 Cardiovascular Diseases Antibodies  >2 publications with CSF2RB and Cardiovascular Diseases
 Necrosis Antibodies  >2 publications with CSF2RB and Necrosis
 Hemorrhage Antibodies  >1 publications with CSF2RB and Hemorrhage
 Lung Neoplasms Antibodies  >1 publications with CSF2RB and Lung Neoplasms
 Cell Transformation, Neoplastic Antibodies  >1 publications with CSF2RB and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >26 publications with CSF2RB and Blood
 Lung Antibodies  >10 publications with CSF2RB and Lung
 Bone Marrow Antibodies  >8 publications with CSF2RB and Bone Marrow
 Bone Antibodies  >8 publications with CSF2RB and Bone
 Brain Antibodies  >5 publications with CSF2RB and Brain
 Vascular Antibodies  >5 publications with CSF2RB and Vascular
 Skin Antibodies  >1 publications with CSF2RB and Skin
 Intestine Antibodies  >1 publications with CSF2RB and Intestine
 Muscle Antibodies  >1 publications with CSF2RB and Muscle
 Connective Tissue Antibodies  >1 publications with CSF2RB and Connective Tissue
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