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ENGASE recombinant protein :: Cytosolic endo-beta-N-acetylglucosaminidase (ENGASE) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1410145 ENGASE recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,145 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,145 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,375 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,375 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,810 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,810 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,270 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,270 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,270 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $3,570 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cytosolic endo-beta-N-acetylglucosaminidase (ENGASE), Recombinant Protein

 Also Known As   

Recombinant Human Cytosolic endo-beta-N-acetylglucosaminidase (ENGASE)

 Product Synonym Names    Cytosolic endo-beta-N-acetylglucosaminidase; ENGase; EC=3.2.1.96
 Product Gene Name   

ENGASE recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-377, The full length of Isoform 2 (identifier: Q8NFI3-2).
 Sequence    MEAAAVTVTR SATRRRRRQL QGLAAPEAGT QEEQEDQEPR PRRRRPGRSI KDEEEETVFR EVVSFSPDPL PVRYYDKDTT KPISFYLSSL EELLAWKPRL EDGFNVALEP LACRQPPLSS QRPRTLLCHD MMGGYLDDRF IQGSVVQTPY AFYHWQCIDV FVYFSHHTVT IPPVGWTNTA HRHGVCVLGT FITEWNEGGR LCEAFLAGDE RSYQAVADRL VQITQFFRFD GWLINIENSL SLAAVGNMPP FLRYLTTQLH RQVPGGLVLW YDSVVQSGQL KWQDELNQHN RVFFDSCDGF FTNYNWREEH LERMLGQAGE RRADVYVGVD VFARGNVVGG RFDTDKSLEL IRKHGFSVAL FAPSCSVFPG VGNLLCC
 OMIM    611898
 3D Structure    ModBase 3D Structure for Q8NFI3
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ENGASE recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ENGASE. It may not necessarily be applicable to this product.
 NCBI GI #    110431350
 NCBI GeneID    64772
 NCBI Accession #    NP_001036038.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001042573.2 [Other Products]
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 UniProt Primary Accession #    Q8NFI3 [Other Products]
 UniProt Secondary Accession #    Q659F0; Q8TB86; Q9H6U4 [Other Products]
 UniProt Related Accession #    Q8NFI3 [Other Products]
 Molecular Weight    46,090 Da
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 NCBI Official Full Name    cytosolic endo-beta-N-acetylglucosaminidase
 NCBI Official Synonym Full Names    endo-beta-N-acetylglucosaminidase
 NCBI Official Symbol    ENGASE [Similar Products]
 NCBI Protein Information    cytosolic endo-beta-N-acetylglucosaminidase; Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase; Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
 UniProt Protein Name    Cytosolic endo-beta-N-acetylglucosaminidase
 Protein Family    Cytosolic endo-beta-N-acetylglucosaminidase
 UniProt Gene Name    ENGASE [Similar Products]
 UniProt Synonym Gene Names    ENGase [Similar Products]
 UniProt Entry Name    ENASE_HUMAN
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 NCBI Summary for ENGASE    This gene encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides. [provided by RefSeq, Feb 2012]
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 UniProt Comments for ENGASE    ENGASE: Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core. Involved in the processing of free oligosaccharides in the cytosol. Belongs to the glycosyl hydrolase 85 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.2.1.96; Hydrolase; Glycan Metabolism - other glycan degradation

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: cytosol

Molecular Function: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity

Biological Process: metabolic process
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 Research Articles on ENGASE    1. Serological N-acetyl-glucosaminidase, telomere length, and the UCP2-886G>A variant are independent risk factors for type 2 diabetes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ENGASE recombinant proteinPathways associated with ENGASE recombinant protein
 Reference Product  PubMed Publications
 NGLY1 recombinant protein  >1 publications with ENGASE and NGLY1
 Products by Pathway  Pathway Diagram
 Other Glycan Degradation Pathway antibodies  Other Glycan Degradation Pathway Diagram
 Other Glycan Degradation Pathway antibodies  Other Glycan Degradation Pathway Diagram
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